Patents by Inventor Lakshmi A. Devi

Lakshmi A. Devi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of screening compounds useful for treatment of a liver disease
    Patent number: 11141423
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: October 12, 2021
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld
  • ANTIBODIES WHICH BIND TYPE I CANNABINOID RECEPTOR/ANGIOTENSIS II RECEPTOR HETEROMERS
    Publication number: 20190374565
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Application
    Filed: June 12, 2019
    Publication date: December 12, 2019
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld
  • ANTIBODIES WHICH BIND TYPE I CANNABINOID RECEPTOR/ANGIOTENSIS II RECEPTOR HETEROMERS
    Publication number: 20180250322
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Application
    Filed: December 12, 2017
    Publication date: September 6, 2018
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld
  • Antibodies which bind type I cannabinoid receptor/angiotensin II receptor heteromers and methods of use
    Patent number: 9855290
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: January 2, 2018
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld
  • Pharmaceutical composition for treating medical conditions and a method for treating alimentary disorders and related diseases
    Patent number: 9452196
    Abstract: The present invention refers to a pharmaceutical composition that includes an active ingredient, such as a peptide, which acts as an antagonist and/or inverse agonist of a G protein-coupled receptor and pharmaceutically acceptable vehicle. The pharmaceutical composition may be used for the treatment of obesity and the prevention of and the treatment of diabetes.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: September 27, 2016
    Assignee: Sociedade Beneficente de Senhoras Hospital Sirio Libanes
    Inventors: Andrea Sterman Heimann, Camila Squarzoni Dale, Lakshmi A. Devi
  • ANTIBODIES WHICH BIND TYPE I CANNABINOID RECEPTOR/ANGIOTENSIS II RECEPTOR HETEROMERS
    Publication number: 20160200822
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Application
    Filed: December 1, 2015
    Publication date: July 14, 2016
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld
  • Antibodies which bind type I cannabinoid receptor/angiotensis II receptor heteromers
    Patent number: 9216189
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: December 22, 2015
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld
  • PHARMACEUTICAL COMPOSITION FOR TREATING MEDICAL CONDITIONS AND A METHOD FOR TREATING ALIMENTARY DISORDERS AND RELATED DISEASES
    Publication number: 20150297669
    Abstract: The present invention refers to a pharmaceutical composition that comprises an active ingredient, such as a peptide, which acts as an antagonist and/or inverse agonist of a G protein-coupled receptor and pharmaceutically acceptable vehicle. Said pharmaceutical composition may be used for the treatment of obesity and the prevention of and the treatment of diabetes.
    Type: Application
    Filed: May 4, 2015
    Publication date: October 22, 2015
    Inventors: Andrea Sterman Heimann, Camila Squarzoni Dale, Lakshmi A. Devi
  • PHARMACEUTICAL COMPOSITION FOR TREATING MEDICAL CONDITIONS AND A METHOD FOR TREATING ALIMENTARY DISORDERS AND RELATED DISEASES
    Publication number: 20130196904
    Abstract: The present invention refers to a pharmaceutical compositions that comprises an active ingredient, such as a peptide, which acts as an antagonist and/or inverse agonist of a G protein-coupled receptor and pharmaceutically acceptable vehicle.
    Type: Application
    Filed: July 30, 2010
    Publication date: August 1, 2013
    Applicant: SOCIEDADE BENEFICENTE DE DENORAS HOSPITAL SIRIO LIBANES
    Inventors: Andrea Sterman Heimann, Camila Squarzoni Dale, Lakshmi A. Devi
  • METHODS OF TREATING LIVER DISEASE
    Publication number: 20130171145
    Abstract: Compounds and compositions useful for the treatment of liver diseases and methods of treating liver diseases are disclosed. The compounds of the invention specifically interact with heteromers of cannabinoid receptors as compared to monomers or homodimers. The invention also relates to methods of screening for compounds useful for the treatment of liver diseases and to methods of screening for diacylglycerol lipase inhibitors.
    Type: Application
    Filed: January 25, 2011
    Publication date: July 4, 2013
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE
    Inventors: Lakshmi A. Devi, Raphael Rozenfeld