Patents by Inventor Lakshmi K. Mannepalli

Lakshmi K. Mannepalli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing diltiazem using a heterogeneous trifunctional catalyst
    Patent number: 6881839
    Abstract: The present invention comprises a simplified synthesis of (+)-diltiazem through IE-PdOsW wherein IE is ion-exchanger, catalyzed three-component coupling reaction and Fe3+-exchanged clay catalyzed ring opening of sulfite with 2-aminothiophenol followed by cyclization as key steps.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: April 19, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Boyapati M. Choudary, Naidu S. Chowdari, Sateesh Madhi, Lakshmi K. Mannepalli
  • Process for preparing diltiazem using a heterogeneous trifunctional catalyst
    Publication number: 20040127704
    Abstract: The present invention comprises a simplified synthesis of (+)-diltiazem through IE-PdOsW wherein IE is ion-exchanger, catalyzed three-component coupling reaction and Fe3+-exchanged clay catalyzed ring opening of sulfite with 2-aminothiophenol followed by cyclization as key steps.
    Type: Application
    Filed: December 31, 2002
    Publication date: July 1, 2004
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Boyapati M. Choudary, Naidu S. Chowdari, Sateesh Madhi, Lakshmi K. Mannepalli
  • Process for preparing taxol side chain using heterogeneous trifunctional catalyst
    Patent number: 6706901
    Abstract: The present invention relates to an improved process for the preparation of taxol side chain by synthesizing (2R,3S)-2,3-dihydroxy-3-phenylpropionate with greater than 99% enantioselectivity and devoid of osmium even in crude form in a single pot using a recyclable multifunctional catalysts, conversion of diol obtained without further crystallization into bromoacetate, reaction of bromoacetate with NaN3 in organic solvent followed by deacetylation with to obtain azido alcohol, benzoylation followed by hydrogenation of azido alcohol to obtain the (2R,3S)-(N-)-benzoyl-3-phenylisoserine methyl ester in 67% yield.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: March 16, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Boyapati M. Choudary, Naidu S. Chowdari, Sateesh Madhi, Lakshmi K. Mannepalli, Jyothi Karangula