Patents by Inventor Lakshmi Prasad ALAPARTHI

Lakshmi Prasad ALAPARTHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of Deutetrabenazine
    Patent number: 11505549
    Abstract: A novel process for preparation of Deutetrabenazine ((RR, SS)-1,3,4,6,7-11b-Hexahydro-9,10-di(methoxy-d6)-3-(2-methylpropyl)-2H-benzo [a] quinolizin-2-one) of formula I comprises of methylation of N-(2-(3,4-dihydroxy-phenyl)-ethyl)-formamide compound of formula III with deuteriated methanol (CD3OD or CD3OH) to obtain d6-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-formamide compound of formula IV; cyclization of d6-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-formamide in presences of dehydrating agent to obtain d6-6,7-Dimethoxy-3,4-dihydroisoquinoline compound of formula V; reacting d6-6,7-Dimethoxy-3,4-dihydroisoquinoline compound of formula V with 2-acetyl-N,N,N,4-tetramethyl-1-pentanaminium iodide compound of formula VI.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: November 22, 2022
    Inventor: Lakshmi Prasad Alaparthi
  • Processes for preparation of Sugammadex and intermediates thereof
    Patent number: 10494450
    Abstract: The present invention relates to a process for preparation of 6-perdeoxy-6-per-chloro gamma-cyclodextrin which is a key intermediate useful in the synthesis of Sugammadex sodium. The present invention further relates to a process for preparation and purification of Sugammadex sodium.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: December 3, 2019
    Inventor: Lakshmi Prasad Alaparthi
  • PROCESSES FOR PREPARATION OF SUGAMMADEX AND INTERMEDIATES THEREOF
    Publication number: 20180171033
    Abstract: The present invention relates to a process for preparation of 6-perdeoxy-6-per-chloro gamma-cyclodextrin which is a key intermediate useful in the synthesis of Sugammadex sodium. The present invention further relates to a process for preparation and purification of Sugammadex sodium.
    Type: Application
    Filed: May 27, 2016
    Publication date: June 21, 2018
    Inventor: Lakshmi Prasad ALAPARTHI