Patents by Inventor Lakshmi Prasad Dasi
Lakshmi Prasad Dasi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11931109Abstract: In certain aspects of the present disclosure, a computer-implemented method includes receiving a 3D imaging. The method includes generating 3D models based on the 3D imaging. The method includes generating, responsive to a pre-determined set of surgical steps, a finite number of 4D time deformation scenes for each pre-determined surgical step associated with the 3D models. The method includes displaying selectively interactive simulations based on the finite number of 4D time deformation scenes. Systems and machine-readable media are also provided.Type: GrantFiled: August 15, 2023Date of Patent: March 19, 2024Assignee: DASISIMULATIONS, LLCInventors: Taylor Nicole Becker, Breandan Yeats, Robert Gerdisch, Lakshmi Prasad Dasi
-
Publication number: 20240050157Abstract: In certain aspects of the present disclosure, a computer-implemented method includes receiving a 3D imaging. The method includes generating 3D models based on the 3D imaging. The method includes generating, responsive to a pre-determined set of surgical steps, a finite number of 4D time deformation scenes for each pre-determined surgical step associated with the 3D models. The method includes displaying selectively interactive simulations based on the finite number of 4D time deformation scenes. Systems and machine-readable media are also provided.Type: ApplicationFiled: August 15, 2023Publication date: February 15, 2024Inventors: Taylor Nicole Becker, Breandan Yeats, Robert Gerdisch, Lakshmi Prasad Dasi
-
Publication number: 20230310080Abstract: A computer implemented method to automatically measure structural features of anatomies using an automatic measurement system, the method includes receiving medical images of the anatomies. The method includes detecting landmarks of the anatomies based on the medical images using an artificial intelligence (AI)-based model and constructing an anatomical structural model of the anatomies based on the detected landmarks. The method includes making quantifying measurements of selected structural features of the anatomical structural model and generating a report including the quantifying measurements.Type: ApplicationFiled: March 31, 2023Publication date: October 5, 2023Inventors: Beom Jun Lee, Lakshmi Prasad Dasi
-
Publication number: 20230146082Abstract: A prosthetic heart valve includes a first upper frame portion and a stent frame connected to the first upper frame portion via at least two stent frame extensions. The stent frame includes a base and at least two stent posts extending upwardly from the base towards the first upper frame portion. The first upper frame portion, the base, and the at least two stent posts each has an inner surface and an outer surface. The prosthetic heart valve also includes at least one sheet of leaflet material configured to encircle the stent frame and weave through the stent frame between the first upper frame portion and the base.Type: ApplicationFiled: November 30, 2022Publication date: May 11, 2023Applicant: Ohio State Innovation FoundationInventors: Lakshmi Prasad Dasi, Atieh Yousefi Koupaei, Megan Kristine Heitkemper
-
Publication number: 20220392642Abstract: A computer implemented method for prescribing optimized medical interventions includes retrieving a patient's updated electronic medical record (EMR) and mapping the diagnosis of the patient to a medical treatment database to select a plurality of likely medical intervention choices based on a score exceeding a defined threshold score. The method includes determining a rank order of the selected plurality of medical intervention choices by comparing simulation outcomes for each choice executed by the medical predictive algorithm, on respective choices among each of the selected likely medical interventions. The method also includes receiving by the patient's physician or patient's electronic medical record database, a rank order of recommended medical intervention choices including possible options and associated metrics based on an accepted level of simulated outcome.Type: ApplicationFiled: June 6, 2022Publication date: December 8, 2022Inventors: Lakshmi Prasad Dasi, Theresa L. Sirset
-
Publication number: 20220346709Abstract: The present invention is directed to a system for monitoring the functional status of an implantable heart valve. The system includes wireless pressure sensors that are embedded in the implantable heart valve. An external device receives signal transmitted from the wireless pressure sensors. The external device reads and analyzes these signals and then transmits the data to a healthcare provider.Type: ApplicationFiled: June 22, 2020Publication date: November 3, 2022Inventors: Rajat Mittal, Jung Hee Seo, Lakshmi Prasad Dasi, Hoda Hatoum, Shantanu Bailoor
-
Publication number: 20220133474Abstract: A transcatheter prosthetic heart valve includes a stent frame and a leaflet material. The stent frame includes a top portion and a bottom portion. The leaflet material includes a lower portion attached to the stent frame and an upper portion that includes leaflets capable of moving between an open configuration and a closed configuration. At least a portion of the leaflet material weaves through the stent frame. The transcatheter prosthetic heart valve also includes one or more reinforcement components coupled to the stent frame and/or to the leaflet material to enhance performance of the transcatheter heart valve.Type: ApplicationFiled: January 14, 2022Publication date: May 5, 2022Applicants: Ohio State Innovation Foundation, Georgia Institute of Technology, Colorado State University Research FoundationInventors: Hieu Bui, Lakshmi Prasad Dasi, Megan Heitkemper, Susan James, Nipa Khair
-
Publication number: 20220087817Abstract: A transcatheter prosthetic heart valve includes a stent frame and at least one sheet of leaflet material formed in to a tube, which includes a lower portion disposed on an exterior of the stent frame and an upper edge portion disposed within the stent frame. The upper edge portion includes at least a portion configured to wrap around a first portion of the top edge of the stent frame and fold towards an exterior of the stent frame. The upper edge portion also includes at least another portion configured to weave through the stent frame and fold towards the interior of the stent frame.Type: ApplicationFiled: December 7, 2021Publication date: March 24, 2022Applicant: Ohio State Innovation FoundationInventors: Lakshmi Prasad Dasi, Atieh Yousefi Koupaei, Megan Kristine Heitkemper
-
Patent number: 11224509Abstract: A transcatheter prosthetic heart valve includes a stent frame and at least one sheet of leaflet material formed in to a tube, which includes a lower portion disposed on an exterior of the stent frame and an upper edge portion disposed within the stent frame. The upper edge portion includes at least a portion configured to wrap around a first portion of the top edge of the stent frame and fold towards an exterior of the stent frame. The upper edge portion also includes at least another portion configured to weave through the stent frame and fold towards the interior of the stent frame.Type: GrantFiled: June 29, 2018Date of Patent: January 18, 2022Assignee: Ohio State Innovation FoundationInventors: Lakshmi Prasad Dasi, Atieh Yousefi Koupaei, Megan Kristine Heitkemper
-
Publication number: 20210346097Abstract: Methods for determining likelihood of thrombosis based on patient-specific anatomic, valve, and flow parameters are disclosed herein. Such methods are used to select a transcatheter aortic valve that decreases likelihood of thrombosis after TAVR procedures. The methods correlate a number of fluid flow and geometric parameters such as stasis volume, neo-sinus volume, kinematic viscosity, dynamic viscosity, heart rate, the circulation, ejection time, velocity of the main jet, wall shear stress, total kinetic energy in the neo sinus volume, width of the neo-sinus, height or depth of the neo-sinus, the angle between the velocity direction and the stent of the transcatheter valve, the distance from the tip of the leaflet perpendicular to the leaflet edge and intersecting the sinotubular junction, and the cross-sectional area of the neo-sinus taken from a longitudinal or axial perspective. Such parameters are used to derive empirical or semi-empirical mathematical models to determine the likelihood of thrombosis.Type: ApplicationFiled: July 22, 2021Publication date: November 11, 2021Applicants: Ohio State Innovation Foundation, Georgia Tech Research CorporationInventors: Lakshmi Prasad Dasi, Amirsepehr Azimian, Hoda Hatoum, Shelly Singh-Gryzbon, Vinod Thourani, Ajit Yoganathan
-
Publication number: 20210145572Abstract: A prosthetic heart valve includes a first upper frame portion and a stent frame connected to the first upper frame portion via at least two stent frame extensions. The stent frame includes a base and at least two stent posts extending upwardly from the base towards the first upper frame portion. The first upper frame portion, the base, and the at least two stent posts each has an inner surface and an outer surface. The prosthetic heart valve also includes at least one sheet of leaflet material configured to encircle the stent frame and weave through the stent frame between the first upper frame portion and the base.Type: ApplicationFiled: June 29, 2018Publication date: May 20, 2021Applicant: Ohio State Innovation FoundationInventors: Lakshmi Prasad Dasi, Atieh Yousefi Koupaei, Megan Kristine Heitkemper
-
Publication number: 20210145573Abstract: A transcatheter prosthetic heart valve includes a stent frame and at least one sheet of leaflet material formed in to a tube, which includes a lower portion disposed on an exterior of the stent frame and an upper edge portion disposed within the stent frame. The upper edge portion includes at least a portion configured to wrap around a first portion of the top edge of the stent frame and fold towards an exterior of the stent frame. The upper edge portion also includes at least another portion configured to weave through the stent frame and fold towards the interior of the stent frame.Type: ApplicationFiled: June 29, 2018Publication date: May 20, 2021Applicant: Ohio State Innovation FoundationInventors: Lakshmi Prasad Dasi, Atieh Yousefi Koupaei
-
Patent number: 10598170Abstract: The devices and systems are medical fluid treatment therapies. The device and systems are configured and capable of operating based on small volumes of fluids. The devices and systems include a pump configured for small volume of a fluid. The pump may include a first conduit configured for inflow of the fluid; a second conduit configured for outflow of the fluid; a fluid chamber configured to move the fluid through the pump; a diaphragm configured to force the fluid through the fluid chamber by indirectly exerting force on the fluid chamber; and a connector configured to removably attach the pump to a motor.Type: GrantFiled: August 4, 2014Date of Patent: March 24, 2020Assignees: Georgia Tech Research Corporation, Emory University, Children's Healthcare of Atlanta, Inc.Inventors: Matthew L. Paden, Ajit P. Yoganathan, Lakshmi Prasad Dasi
-
Patent number: 10071186Abstract: Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.Type: GrantFiled: March 11, 2013Date of Patent: September 11, 2018Assignee: Colorado State University Research FoundationInventors: Susan P. James, Harold Dean, IV, Lakshmi Prasad Dasi, Marcio H. Forleo, Ketul C. Popat, Nicole R. Lewis, David Alois Prawel
-
Publication number: 20150196688Abstract: Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.Type: ApplicationFiled: March 11, 2013Publication date: July 16, 2015Applicant: Colorado State University Research FoundationInventors: Susan P. James, Harold Dean, IV, Lakshmi Prasad Dasi, Marcio H. Forleo, Ketul C. Popat, Nicole R. Lewis, David Alois Prawel
-
Publication number: 20140341756Abstract: The devices and systems are medical fluid treatment therapies. The device and systems are configured and capable of operating based on small volumes of fluids. The devices and systems include a pump configured for small volume of a fluid. The pump may include a first conduit configured for inflow of the fluid; a second conduit configured for outflow of the fluid; a fluid chamber configured to move the fluid through the pump; a diaphragm configured to force the fluid through the fluid chamber by indirectly exerting force on the fluid chamber; and a connector configured to removably attach the pump to a motor.Type: ApplicationFiled: August 4, 2014Publication date: November 20, 2014Inventors: Matthew L. Paden, Ajit P. Yoganathan, Lakshmi Prasad Dasi
-
Patent number: 8834911Abstract: A device for use in combination with a fluid flow having a biologic component and subject to an adverse response to shear stress includes a surface in contact with the flow of the fluid. The surface has a longitudinal direction extending from a leading end toward a trailing end and aligned with a direction of the flow. The surface is susceptible to inducing boundary layer formation within the flow sufficient for a resulting shear stress to induce the response. The surface includes a surface feature sufficient to induce boundary layer tripping in the flow to retard growth of boundary layer formation along the length.Type: GrantFiled: November 15, 2007Date of Patent: September 16, 2014Assignee: Georgia Tech Research CorporationInventors: Ari Glezer, Ajit P. Yoganathan, Lakshmi Prasad Dasi
-
Patent number: 8821135Abstract: The devices and systems are medical fluid treatment therapies. The device and systems are configured and capable of operating based on small volumes of fluids. The devices and systems include a pump configured for small volume of a fluid. The pump may include a first conduit configured for inflow of the fluid; a second conduit configured for outflow of the fluid; a fluid chamber configured to move the fluid through the pump; a diaphragm configured to force the fluid through the fluid chamber by indirectly exerting force on the fluid chamber; and a connector configured to removably attach the pump to a motor.Type: GrantFiled: August 25, 2011Date of Patent: September 2, 2014Assignees: Emory University, Georgia Tech Research CorporationInventors: Matthew L. Paden, Ajit Yoganathan, Lakshmi Prasad Dasi
-
Patent number: 8206594Abstract: A novel system and method for fluid management for accurate continuous venovenous hemofiltration (CWH) in extracorporeal membrane oxygenation (ECMO). The fluid management or CWH system is automated and configured for operation as a stand alone unit and can be easily integrated with an ECMO system. The fluid management system is capable of producing either perfect or negative fluid balance between ultrafiltrate removal and replacement fluid delivery. The fluid management system can achieve electrolyte replacement over a range of flow rates needed to care for patients ranging from neonates to adults. Finally, the novel fluid management system preserves patient safety, maintains sterility during operation, is easy to operate, and is compact enough to fit near a patient's bed.Type: GrantFiled: June 6, 2008Date of Patent: June 26, 2012Assignees: Emoery University, Children's Healthcare of Atlanta, Georgia Tech Research CorporationInventors: James D. Fortenberry, Ajit P. Yoganathan, Philippe Sucosky, Lakshmi Prasad Dasi, Matthew L. Paden
-
Publication number: 20120048407Abstract: The devices and systems are medical fluid treatment therapies. The device and systems are configured and capable of operating based on small volumes of fluids. The devices and systems include a pump configured for small volume of a fluid. The pump may include a first conduit configured for inflow of the fluid; a second conduit configured for outflow of the fluid; a fluid chamber configured to move the fluid through the pump; a diaphragm configured to force the fluid through the fluid chamber by indirectly exerting force on the fluid chamber; and a connector configured to removably attach the pump to a motor.Type: ApplicationFiled: August 25, 2011Publication date: March 1, 2012Applicants: GEORGIA TECH RESEARCH CORPORATION, EMORY UNIVERSITYInventors: Matthew L. Paden, Ajit Yoganathan, Lakshmi Prasad Dasi