Patents by Inventor Lalit Venkatesan
Lalit Venkatesan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11964152Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.Type: GrantFiled: May 6, 2019Date of Patent: April 23, 2024Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Filippo Agnesi, Lalit Venkatesan, Christopher S. L. Crawford
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Publication number: 20200353269Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.Type: ApplicationFiled: May 6, 2019Publication date: November 12, 2020Inventors: Filippo Agnesi, Lalit Venkatesan
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Publication number: 20200353255Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. in some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.Type: ApplicationFiled: May 6, 2019Publication date: November 12, 2020Inventors: Filippo Agnesi, Lalit Venkatesan, Christopher S.L. Crawford
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Patent number: 10806929Abstract: A system and method for performing deep brain stimulation (DBS) therapy are provided. The method and system include pre-operatively acquiring at least one pre-operative image of the brain with at least one imaging sub-system and determining a location of a Nucleus Basalls of Meynert (NBM) for therapy in the at least one pre-operative image, and intra-operatively acquiring at least one intra-operative image of the brain after obtaining an access opening through the skull. The method and system further provide performing surgical planning based on the pre-operative image in the intra-operative image, advancing a lead having DBS electrodes on the lead to a target position proximate to or within the NBM area, and coupling the lead to an implantable pulse generator (IPG) configured to deliver DBS pulses through the DBS electrodes to the NBM. Further, the IPG is configured to deliver DBS pulses for treating symptoms associated with Alzheimer's disease.Type: GrantFiled: May 16, 2018Date of Patent: October 20, 2020Assignee: Pacesetter, Inc.Inventor: Lalit Venkatesan
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Patent number: 10188865Abstract: The present disclosure provides systems and methods for combining tonic deep brain stimulation (DBS) and random DBS. A system includes a stimulation lead including a plurality of contacts, and an implantable pulse generator (IPG) communicatively coupled to the stimulation lead and configured to cause tonic stimulation to be delivered using one contact of the plurality of contacts, and cause random stimulation to be delivered using a subset of the remaining contacts of the plurality of contacts.Type: GrantFiled: June 15, 2016Date of Patent: January 29, 2019Assignee: PACESETTER, INC.Inventors: Filippo Agnesi, Lalit Venkatesan
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Publication number: 20180271743Abstract: A device for stimulating mechanosensory nerve endings can include: a housing having an internal chamber and first and second openings; optionally, a membrane covering the first opening of housing, the membrane being sufficient flexibility to vibrate upon receiving vibratory stimulation from a vibratory mechanism; and a coupling mechanism at the second opening configured for being fluidly coupled to the vibratory mechanism, wherein the entire device is magnetically unresponsive materials. The housing can be cylindrical, or any polygon shape. The membrane can be integrated with the housing or coupled thereto, such as with adhesive. Optionally, the membrane can be removably coupled to the housing. The membrane can be omitted such that the skin of a subject coupled to the device oscillates in response to the fluid vibrations.Type: ApplicationFiled: May 29, 2018Publication date: September 27, 2018Applicant: The University of KansasInventors: Steven M. Barlow, Lalit Venkatesan
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Publication number: 20180256896Abstract: A system and method for performing deep brain stimulation (DBS) therapy are provided. The method and system include pre-operatively acquiring at least one pre-operative image of the brain with at least one imaging sub-system and determining a location of a Nucleus Basalls of Meynert (NBM) for therapy in the at least one pre-operative image, and intra-operatively acquiring at least one intra-operative image of the brain after obtaining an access opening through the skull. The method and system further provide performing surgical planning based on the pre-operative image in the intra-operative image, advancing a lead having DBS electrodes on the lead to a target position proximate to or within the NBM area, and coupling the lead to an implantable pulse generator (IPG) configured to deliver DBS pulses through the DBS electrodes to the NBM. Further, the IPG is configured to deliver DBS pulses for treating symptoms associated with Alzheimer's disease.Type: ApplicationFiled: May 16, 2018Publication date: September 13, 2018Inventor: Lalit Venkatesan
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Patent number: 9999772Abstract: A system and method for performing deep brain stimulation (DBS) therapy are provided. The method and system include pre-operatively acquiring at least one pre-operative image of the brain with at least one imaging sub-system and determining a location of a Nucleus Basalis of Meynert (NBM) for therapy in the at least one pre-operative image, and intra-operatively acquiring at least one intra-operative image of the brain after obtaining an access opening through the skull. The method and system further provide performing surgical planning based on the pre-operative image in the intra-operative image, advancing a lead having DBS electrodes on the lead to a target position proximate to or within the NBM area, and coupling the lead to an implantable pulse generator (IPG) configured to deliver DBS pulses through the DBS electrodes to the NBM. Further, the IPG is configured to deliver DBS pulses for treating symptoms associated with Alzheimer's disease.Type: GrantFiled: April 3, 2014Date of Patent: June 19, 2018Assignee: PACESETTER, INC.Inventor: Lalit Venkatesan
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Publication number: 20170361105Abstract: The present disclosure provides systems and methods for combining tonic deep brain stimulation (DBS) and random DBS. A system includes a stimulation lead including a plurality of contacts, and an implantable pulse generator (IPG) communicatively coupled to the stimulation lead and configured to cause tonic stimulation to be delivered using one contact of the plurality of contacts, and cause random stimulation to be delivered using a subset of the remaining contacts of the plurality of contacts.Type: ApplicationFiled: June 15, 2016Publication date: December 21, 2017Inventors: Filippo Agnesi, Lalit Venkatesan
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Publication number: 20170259066Abstract: The present disclosure provides systems and methods for disrupting neuronal oscillations. A neurostimulation system includes a stimulation lead comprising at least one contact, and an implantable pulse generator (IPG) communicatively coupled to the stimulation lead and configured to cause stimulation to be applied to a patient using no more than two contacts of the stimulation lead by causing a first burst of stimulation to be delivered, and causing a second burst of stimulation to be delivered within a neuronal refractory period that follows the first burst of stimulation.Type: ApplicationFiled: March 8, 2016Publication date: September 14, 2017Inventors: Edward Karst, Alexander Kent, Lalit Venkatesan, Timothy A. Fayram
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Patent number: 9586039Abstract: A neurostimulation (NS) lead configured to provide NS therapy to nervous tissue. The NS lead includes a lead body having an active side and a posterior side that face in generally opposite directions. The NS lead includes an array of electrodes provided on the active side and configured to face the nervous tissue and provide the NS therapy to the nervous tissue. The NS lead also includes a non-planar contour formed in the active side. The non-planar contour includes a plurality of slopes that form a morphological feature. The morphological feature is one of a projection or a depression that extends along a designated path on the active side.Type: GrantFiled: March 7, 2014Date of Patent: March 7, 2017Assignee: PACESETTER, INC.Inventors: Gene A. Bornzin, Lalit Venkatesan
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Patent number: 9498627Abstract: A wireless implantable system is provided that is externally powered and comprises of a closed-loop feedback for treating both patients with obstructive and central sleep apnea. A method is provided for treating sleep apnea using an implantable device. The method comprises sensing an inspiration (IN) signal representative of inspiration experienced by a patient from a respiratory surrogate signal and sensing a respiratory effort (RE) signal representative of an amount of effort exerted by the patient during respiration.Type: GrantFiled: January 15, 2014Date of Patent: November 22, 2016Assignee: PACESETTER, INC.Inventors: Stuart Rosenberg, Melanie Goodman Keiser, Lalit Venkatesan, Didier Theret
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Patent number: 9421377Abstract: The present disclosure provides systems and methods utilizing a closed-loop neurostimulation apparatus. The apparatus includes at least one sensing electrode that monitors neurological activity of a subject and at least one stimulating electrode that applies stimulation pulses to the subject. An internal pulse generator is coupled to the at least one sensing electrode and the at least one stimulating electrode. The internal pulse generator causes the at least one stimulating electrode to apply stimulating pulses based at least in part on the monitored neurological activity.Type: GrantFiled: December 17, 2013Date of Patent: August 23, 2016Assignee: PACESETTER, INC.Inventors: Lalit Venkatesan, Stuart Rosenberg
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Publication number: 20160206883Abstract: A system and method for current steering a neurostimulation signal is provided. The system and method provide a lead coupled to an implantable pulse generator (IPG). The lead may include a plurality of electrodes. The lead may be configured to be implanted at a target position proximate to tissue of interest. The system and method program the IPG to deliver at least a first pulse train to a first electrode and a second pulse train to a second electrode. The first and second pulse trains are interleaved with one another such that the first and second pulse trains form an activation current density distribution steered to overlay the tissue of interest.Type: ApplicationFiled: January 19, 2015Publication date: July 21, 2016Inventors: Gene A. Bornzin, Lalit Venkatesan, Yelena Nabutovsky, Riddhi Shah, Rupinder Bharmi, Edward Karst, Alexander Kent, Xiaoyi Min
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Publication number: 20160089541Abstract: In one embodiment, a neurostimulation system for stimulating neuronal tissue of a brain of a patient, comprises: an implantable pulse generator comprising pulse generating circuitry and a controller; one or more stimulation leads comprising multiple electrodes, the implantable pulse generator adapted to connect to the one or more stimulation leads for delivery of generated electrical pulses to neuronal tissue of the patient; wherein the controller is adapted to control the implantable pulse generator to (i) generate a plurality of bursts of multiple pulses at a frequency of at least 100 Hz and (ii) to deliver each respective bursts on a randomly or pseudo-randomly selected electrode from multiple electrodes of the one or more stimulation leads, wherein a beginning of each burst in the plurality of bursts is separated from a beginning of its respective successive bursts by at least 50 milliseconds.Type: ApplicationFiled: September 29, 2015Publication date: March 31, 2016Inventor: Lalit Venkatesan
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Patent number: 9247895Abstract: A method for performing deep brain stimulation (DBS) therapy may include determining a location of a target area of a brain, forming a burr hole through a skull of a patient based on the location the target area, positioning one or more reference members on or within the brain through the burr hole, and acquiring at least one image of the brain having the one or more reference members with at least one imaging sub-system.Type: GrantFiled: March 21, 2014Date of Patent: February 2, 2016Assignee: Pacesetter, Inc.Inventors: Lalit Venkatesan, Gene A. Bornzin, Rupinder Bharmi, Yelena Nabutovsky, Riddhi Shah, Kevin Wilson
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Patent number: 9174052Abstract: The present disclosure provides systems and methods for neurostimulation. The method includes applying electrical stimulation to a patient using a paddle lead that includes a plurality of electrodes, acquiring local impedances associated with at least some of the plurality of electrodes, wherein the local impedances are indicative of electrode-tissue contact and effectiveness of the electrical stimulation, transmitting the local impedances data to a computing device, and processing the local impedances data using the computing device to adjust the amplitude of stimulations and electrode configurations, and monitor electrode-tissue contact status over time.Type: GrantFiled: July 10, 2014Date of Patent: November 3, 2015Assignee: Pacesetter, Inc.Inventors: Yelena Nabutovsky, Fujian Qu, Lalit Venkatesan, Kyungmoo Ryu
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Publication number: 20150283379Abstract: A system and method for performing deep brain stimulation (DBS) therapy are provided. The method and system include pre-operatively acquiring at least one pre-operative image of the brain with at least one imaging sub-system and determining a location of a Nucleus Basalis of Meynert (NBM) for therapy in the at least one pre-operative image, and intra-operatively acquiring at least one intra-operative image of the brain after obtaining an access opening through the skull. The method and system further provide performing surgical planning based on the pre-operative image in the intra-operative image, advancing a lead having DBS electrodes on the lead to a target position proximate to or within the NBM area, and coupling the lead to an implantable pulse generator (IPG) configured to deliver DBS pulses through the DBS electrodes to the NBM. Further, the IPG is configured to deliver DBS pulses for treating symptoms associated with Alzheimer's disease.Type: ApplicationFiled: April 3, 2014Publication date: October 8, 2015Applicant: PACESETTER, INC.Inventor: Lalit Venkatesan
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Publication number: 20150265180Abstract: A method for performing deep brain stimulation (DBS) therapy may include determining a location of a target area of a brain, forming a burr hole through a skull of a patient based on the location the target area, positioning one or more reference members on or within the brain through the burr hole, and acquiring at least one image of the brain having the one or more reference members with at least one imaging sub-system.Type: ApplicationFiled: March 21, 2014Publication date: September 24, 2015Applicant: PACESETTER, INC.Inventors: Lalit Venkatesan, Gene A. Bornzin, Rupinder Bharmi, Yelena Nabutovsky, Riddhi Shah, Kevin Wilson
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Publication number: 20150251003Abstract: A neurostimulation (NS) lead configured to provide NS therapy to nervous tissue. The NS lead includes a lead body having an active side and a posterior side that face in generally opposite directions. The NS lead includes an array of electrodes provided on the active side and configured to face the nervous tissue and provide the NS therapy to the nervous tissue. The NS lead also includes a non-planar contour formed in the active side. The non-planar contour includes a plurality of slopes that form a morphological feature. The morphological feature is one of a projection or a depression that extends along a designated path on the active side.Type: ApplicationFiled: March 7, 2014Publication date: September 10, 2015Applicant: PACESETTER, INC.Inventors: Gene A. Bornzin, Lalit Venkatesan