Patents by Inventor Lam N. Tran
Lam N. Tran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240027390Abstract: Analyte sensor comprises a substrate having an upper surface including a first portion and a second exposed portion, an electrode layer disposed on the first portion and having an elongate body comprising a proximal end and a distal end, the electrode layer including an active working electrode area having a surface area of between 0.15 mm2 to 0.25 mm2, at least one sensing spot with at least one analyte responsive enzyme disposed on the active working electrode area. Additional analyte sensors are disclosed.Type: ApplicationFiled: July 18, 2023Publication date: January 25, 2024Applicant: ABBOTT DIABETES CARE INC.Inventors: Udo Hoss, Max Garbett, Andrew James Bull, Stephen Oja, Benjamin J. Feldman, Lam N. Tran, Jean-Pierre Babka, Mark Stephen Yahnke, Tahir S. Khan, Adrian Petyt, Mark Alan Schulz, Andrew McGibbon, Owen Daniel Reynolds
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Publication number: 20230225615Abstract: Various embodiments of systems, devices and methods for improving the accuracy of an analyte sensor and for detecting sensor fault conditions are disclosed. According to some embodiments, these systems, devices, and methods can utilize a first data collected by a glucose sensor and a second data collected by a secondary sensing element. In some embodiments, the secondary sensing element can be one of a lactate sensing element, a ketone sensing element, or a heart rate monitor, among others.Type: ApplicationFiled: June 7, 2021Publication date: July 20, 2023Inventors: Erwin S. Budiman, Yi Wang, Benjamin Jay Feldman, Hyun Cho, Kuan-Chou Chen, Lam N. Tran, Stephen Oja, Tianmei Ouyang
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Publication number: 20220386910Abstract: Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.Type: ApplicationFiled: August 11, 2022Publication date: December 8, 2022Applicant: ABBOTT DIABETES CARE INC.Inventors: Stephen OJA, Tianmei Ouyang, Hyun Cho, Lam N. Tran, Benjamin J. Feldman, Mark K. Sloan, AShwin Kumar, Namvar Kiaie, Michael R. Love
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Publication number: 20220183595Abstract: Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor for sensing an analyte level in a bodily fluid of a subject. A sensor insertion component may include a small diameter needle disposed at an angle of about 7 to about 10 degrees to a skin normal insertion force vector with a flexible elongate sensor and sharpened tip supported by a U-shaped protector along an intermediate portion. Advancing the needle into the subject along the vector causes stretching of the skin around the needle, allowing entry of the sensor tip into the body. A bump may be provided on a distal portion of the sensor for engagement by the U-shaped protector and transmission of an insertion force to the sensor tip.Type: ApplicationFiled: December 9, 2021Publication date: June 16, 2022Inventors: Yi Wang, Hyun Cho, Benjamin J. Feldman, Lam N. Tran, Zahid Sadik
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Publication number: 20220007978Abstract: Analyte sensors are being increasingly employed for monitoring various analytes in vivo. Analyte sensors may feature enhancements to address signals obtained from interferent species. Some analyte sensors may comprise a working electrode comprising an active area disposed thereon and electrode asperities laser planed therefrom. Some analyte sensors may comprise an interferent-reactant species incorporated therewith. Some analyte sensors may comprise an interferent scrubbing electrode. Combinations of these enhancements may additionally be employed.Type: ApplicationFiled: June 15, 2021Publication date: January 13, 2022Applicant: ABBOTT DIABETES CARE INC.Inventors: Stephen Oja, Cade Brylee Fox, Lam N. Tran, Zenghe Liu, Benjamin J. Feldman, Udo Hoss, Mark Stephen Yahnke, Tahir S. Khan, Jean-Pierre Babka, Owen Daniel Reynolds
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Publication number: 20210386340Abstract: Analyte sensors are being increasingly employed for monitoring various analytes in vivo. Analyte sensors may feature enhancements to address signals obtained from interferent species. Some analyte sensors may comprise a working electrode having sensing portion and an exposed electrode portion, wherein the sensing portion comprises an active area having an analyte-responsive enzyme disposed thereupon and the exposed electrode portion comprises no active area. The exposed electrode portion and the sensing portion may be present in a ratio of and about 1:10 to about 10:1.Type: ApplicationFiled: June 15, 2021Publication date: December 16, 2021Applicant: ABBOTT DIABETES CARE INC.Inventors: Stephen Oja, Benjamin J. Feldman, Lam N. Tran, Jean-Pierre Babka, Mark Stephen Yahnke, Tahir S. Khan, Max Garbett, Adrian Petyt, Mark Alan Schulz, Andrew McGibbon, Andrew James Bull, Udo Hoss
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Publication number: 20210219885Abstract: Multiple analytes may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using analyte sensors capable of detecting multiple analytes. Certain analyte sensors capable of the detection of multiple analytes may include first and second working electrodes, analyte-responsive active areas disposed on each of the working electrodes, and reference and counter electrodes. Analyte sensors that include multiple working electrodes but do not include reference and counter electrodes can also be used in conjunction with another sensor that contains reference and counter electrodes, such that these electrodes are shared.Type: ApplicationFiled: December 30, 2020Publication date: July 22, 2021Inventors: Yi Wang, Hyun Cho, Benjamin J. Feldman, Kuan-Chou Chen, Lam N. Tran, Stephen Oja, Jonathan D. McCanless
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Publication number: 20210137431Abstract: Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.Type: ApplicationFiled: January 18, 2021Publication date: May 13, 2021Applicant: Abbott Diabetes Care Inc.Inventors: Stephen Oja, Tianmei Ouyang, Hyun Cho, Lam N. Tran, Benjamin J. Feldman, Mark K. Sloan, Ashwin Kumar, Namvar Kiaie, Michael R. Love
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Publication number: 20200237277Abstract: Multiple enzymes may be present in one or more active areas of an electrochemical analyte sensor for detecting one or more different analytes. In particular, an analyte sensor may comprise a sensor tail configured for insertion into a tissue and one or more working electrodes having a glucose-responsive active area and an ethanol-responsive active area to detect glucose and ethanol in vivo.Type: ApplicationFiled: January 28, 2020Publication date: July 30, 2020Applicant: Abbott Diabetes Care Inc.Inventors: Tianmei Ouyang, Benjamin J. Feldman, Hyun Cho, Lam N. Tran, Stephen Oja, Mark K. Sloan, Ashwin Kumar, Namvar Kiaie, Michael R. Love
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Publication number: 20200237276Abstract: Multiple enzymes may be present in the active area(s) of an electrochemical sensor to facilitate analysis of one or more analytes. The multiple enzymes may function independently to detect several analytes or in concert to detect a single analyte. One sensor configuration includes a first active area and a second active area, where the first active area has an oxidation-reduction potential that is sufficiently separated from the oxidation-reduction potential of the second active area to allow independent signal production. Some sensor configurations may have an active area overcoated with a multi-component membrane containing two or more different membrane polymers. Sensor configurations having multiple enzymes capable of interacting in concert include those in which a first enzyme converts an analyte into a first product and a second enzyme converts the first product into a second product, thereby generating a signal at a working electrode that is proportional to the analyte concentration.Type: ApplicationFiled: January 28, 2020Publication date: July 30, 2020Applicant: Abbott Diabetes Care Inc.Inventors: Stephen Oja, Tianmei Ouyang, Hyun Cho, Lam N. Tran, Benjamin J. Feldman, Mark K. Sloan, Ashwin Kumar, Namvar Kiaie, Michael R. Love
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Publication number: 20090095642Abstract: Enzyme-based electrochemical sensors comprising transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators and include substituted or unsubstituted pyridyl-imidazole ligands. Transition metal complexes attached to polymeric backbones are also described.Type: ApplicationFiled: April 14, 2008Publication date: April 16, 2009Inventors: Tianmei Ouyang, Zenghe Liu, John LaTour, Ting Chen, Lam N. Tran, Benjamin Feldman, Fei Mao, Adam Heller
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Publication number: 20030129083Abstract: Multi-purpose solutions for contact lens care provide substantial lens wearer/user comfort and/or acceptability. Such solutions include an aqueous liquid medium; an antimicrobial component, preferably a biguanide polymer present in an amount of less than about 5 ppm; propylene glycol or glycerin in an amount sufficient to increase antimicrobial activity; a surfactant component, preferably a poly(oxyethylene)-poly(oxypropylene) block copolymer surfactant, in an effective amount; a phosphate buffer component in an effective amount; a viscosity inducing component, preferably selected from cellulosic derivatives, in an effective amount; and a tonicity component in an effective amount. Such solutions have substantial performance, comfort and acceptability benefits, which, ultimately, lead to ocular health advantages and avoidance of problems caused by contact lens wear.Type: ApplicationFiled: November 18, 2002Publication date: July 10, 2003Applicant: ADVANCED MEDICAL OPTICS, INC.Inventors: Richard S. Graham, Lam N. Tran