Abstract: A method and apparatus for the low temperature sterilization and disinfections to be applied to medical apparatus/instruments. This invention perfects the use of ultrasonic, UV, ozone in a liquid bath with at least one chemical reagent which can be either sterilant or disinfectant solution for reprocessing many classes of medical equipment/instruments especially those which do not withstand high temperature sterilization process and require sterilization or high level disinfections. The invented method can effectively remove and destroy contaminates, particularly living organisms, bacterial spores, virus, and organics from used or contaminated medical apparatus/instruments surface, inner hollow lumen tube, joints and crevices. Having greatest immediate application for the cleaning, disinfecting and sterilizing all in one simple process for reprocessing used or contaminated medical apparatus/instruments after treating patients.