Patents by Inventor Lambert J. W. M. Tax

Lambert J. W. M. Tax has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical dosage unit
    Patent number: 4914089
    Abstract: The invention relates to a pharmaceutical dosage unit for oral application for preventing or treating climacteric complaints.
    Type: Grant
    Filed: July 6, 1988
    Date of Patent: April 3, 1990
    Assignee: Akzo N.V.
    Inventor: Lambert J. W. M. Tax
  • Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same
    Patent number: 4329296
    Abstract: There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5.alpha.H analog thereof, where R is H or CH.sub.3 ;R.sub.1 is H or CH.sub.3 ;R.sub.2 is H or CH.sub.3 ;R.sub.3 is H, OH, CH.sub.3 or Cl;R.sub.4 is H or C.sub.1 to C.sub.4 alkyl;R.sub.5 is H, C.sub.1 to C.sub.4 alkyl or CF.sub.3 ;R.sub.6 is H, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy,halogen or .beta.--OH providing that when R.sub.6 is .beta.--OH, the steroid also contains 9.alpha.--F.The steroid esters have androgenic, anabolic, oestrogenic or anti-oestrogenic properties depending upon the ring configurations and the substituent(s). Pharmaceutical compositions containing the steroid esters are also disclosed.
    Type: Grant
    Filed: February 12, 1980
    Date of Patent: May 11, 1982
    Assignee: Akzona Incorporated
    Inventor: Lambert J. W. M. Tax
  • Branched chain and cycloaliphatic esters of the androstane and destrane series and pharmaceutical compositions containing same
    Patent number: 4312864
    Abstract: There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5.alpha.H analog thereof. The steroid esters have androgenic, anabolic, oestrogenic or anti-oestrogenic properties depending upon the ring configurations and the substituent(s). Pharmaceutical compositions containing the steroid esters are also disclosed.
    Type: Grant
    Filed: February 12, 1980
    Date of Patent: January 26, 1982
    Assignee: Akzona Incorporated
    Inventor: Lambert J. W. M. Tax
  • Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same
    Patent number: 4307087
    Abstract: There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## where R is H or CH.sub.3 ;R.sub.1 is H or CH.sub.3 ;R.sub.2 is H or CH.sub.3 ;R.sub.3 is H, OH, CH.sub.3 or Cl;R.sub.4 is H or C.sub.1 to C.sub.4 alkyl;R.sub.5 is H, C.sub.1 to C.sub.4 alkyl or CF.sub.3 ;R.sub.6 is H, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halogen or .beta.-OH providing that when R.sub.6 is .beta.-OH, the steroid also contains 9.alpha.-F and further providing that R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 represent at least 4 and at most 5 hydrogen atoms, except in the case of a .DELTA..sup.1,4 -steroid, in which case R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are all hydrogen;R.sub.7 is H or CH.sub.3 ;R.sub.8 is ##STR2## providing the R.sub.8 is --OH or ##STR3## when the steroid has an aromatic ring A.
    Type: Grant
    Filed: February 12, 1980
    Date of Patent: December 22, 1981
    Assignee: Akzona Incorporated
    Inventor: Lambert J. W. M. Tax
  • Branched chain and cycloaliphatic esters of the androstane and destrane series and pharmaceutical compositions containing same
    Patent number: 4307086
    Abstract: There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## where R is H or CH.sub.3 ;R.sub.1 is H or CH.sub.3 ;R.sub.2 is H or CH.sub.3 ;R.sub.3 is H, OH, CH.sub.3 or Cl;R.sub.4 is H or C.sub.1 to C.sub.4 alkyl;R.sub.5 is H, C.sub.1 to C.sub.4 alkyl or CF.sub.3 ;R.sub.6 is H, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halogen or .beta.-OH providing that when R.sub.6 is .beta.-OH, the steroid also contains 9.alpha.-F and further providing that R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 represent at least 4 and at most 5 hydrogen atoms, except in the case of a .DELTA..sup.1,4 -steroid, in which case R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are all hydrogen;R.sub.7 is H or CH.sub.3 ;R.sub.8 is ##STR2## providing the R.sub.8 is --OH or ##STR3## when the steroid has an aromatic ring A and the 3-position is substituted by ##STR4## R.sub.9 is ##STR5## where n is 0, 1 or 2;R.sub.10 is C.sub.1 to C.sub.10 alkyl;R.sub.11 is H or C.sub.
    Type: Grant
    Filed: February 12, 1980
    Date of Patent: December 22, 1981
    Assignee: Akzona Incorporated
    Inventor: Lambert J. W. M. Tax
  • Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same
    Patent number: 4212864
    Abstract: There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5.alpha.H analog thereof, where R is H or CH.sub.3 ;R.sub.1 is H or CH.sub.3 ;R.sub.2 is H or CH.sub.3 ;R.sub.3 is H, OH, CH.sub.3 or Cl;R.sub.4 is H or C.sub.1 to C.sub.4 alkyl;R.sub.5 is H, C.sub.1 to C.sub.4 alkyl or CF.sub.3 ;R.sub.6 is H, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halogen or .beta.-OH providing that when R.sub.6 is .beta.-OH, the steroid also contains 9.alpha.-F and further providing that R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 represent at least 4 and at most 5 hydrogen atoms, except in the case of a .DELTA..sup.1,4 -steroid, in which case R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are all hydrogen;R.sub.7 is H or CH.sub.3 ; ##STR2## providing the R.sub.8 is --OH or ##STR3## when the steroid has an aromatic ring A and the 3-position is substituted by ##STR4## R.sub.9 is ##STR5## where n is 0, 1 or 2;R.sub.10 is C.sub.1 to C.sub.10 alkyl;R.
    Type: Grant
    Filed: November 17, 1977
    Date of Patent: July 15, 1980
    Assignee: Akzona Incorporated
    Inventor: Lambert J. W. M. Tax