Patents by Inventor Lampros Kourtis
Lampros Kourtis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10752768Abstract: Orthopedic implants having a bone interface member and a water swellable IPN or semi-IPN with a stiffness, hydration, and/or composition gradient from one side to the other and physically attached to the bone interface member. The invention also includes an orthopedic implant system including an implant that may conform to a bone surface and a joint capsule. The invention also includes orthopedic implants with water swellable IPN or semi-IPNs including a hydrophobic thermoset or thermoplastic polymer first network and an ionic polymer second network, joint capsules, labral components, and bone interface members. The invention also includes a method of inserting an orthopedic implant having a metal portion and a flexible polymer portion into a joint, including inserting the implant in a joint in a first shape and changing the implant from a first shape to a second shape to conform to a shape of a bone.Type: GrantFiled: March 6, 2020Date of Patent: August 25, 2020Assignee: Hyalex Orthopaedics, Inc.Inventors: David Myung, Michael J. Jaasma, Lampros Kourtis, Curtis W. Frank
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Publication number: 20200239678Abstract: Orthopedic implants having a bone interface member and a water swellable IPN or semi-IPN with a stiffness, hydration, and/or composition gradient from one side to the other and physically attached to the bone interface member. The invention also includes an orthopedic implant system including an implant that may conform to a bone surface and a joint capsule. The invention also includes orthopedic implants with water swellable IPN or semi-IPNs including a hydrophobic thermoset or thermoplastic polymer first network and an ionic polymer second network, joint capsules, labral components, and bone interface members. The invention also includes a method of inserting an orthopedic implant having a metal portion and a flexible polymer portion into a joint, including inserting the implant in a joint in a first shape and changing the implant from a first shape to a second shape to conform to a shape of a bone.Type: ApplicationFiled: March 6, 2020Publication date: July 30, 2020Inventors: David MYUNG, Michael J. JAASMA, Lampros KOURTIS, Curtis W. FRANK
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Publication number: 20200087440Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.Type: ApplicationFiled: November 19, 2019Publication date: March 19, 2020Inventors: Lampros KOURTIS, David MYUNG, Daniel CHANG, Bing YU, Timothy SUN, Michael J. JAASMA, Vernon HARTDEGEN
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Publication number: 20200046880Abstract: The present disclosure pertains to ionic polymer compositions, including semi- and fully interpenetrating polymer networks, methods of making such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging for such articles.Type: ApplicationFiled: October 17, 2019Publication date: February 13, 2020Inventors: Iraklis Kourtis, Jun Li, Lampros Kourtis
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Publication number: 20200023098Abstract: The present disclosure pertains to ionic polymer compositions, including semi- and fully interpenetrating polymer networks, methods of making such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging for such articles.Type: ApplicationFiled: July 17, 2019Publication date: January 23, 2020Inventors: Iraklis Kourtis, Jun Li, Lampros Kourtis
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Publication number: 20200017676Abstract: Orthopedic implants having a bone interface member and a water swellable IPN or semi-IPN with a stiffness, hydration, and/or compositional gradient from one side to the other and physically attached to the bone interface member. The invention also includes an orthopedic implant system including an implant that may conform to a bone surface and a joint capsule. The invention also includes orthopedic implants with water swellable IPN or semi-IPNs including a hydrophobic thermoset or thermoplastic polymer first network and an ionic polymer second network, joint capsules, labral components, and bone interface members. The invention also includes a method of inserting an orthopedic implant having a metal portion and a flexible polymer portion into a joint, including inserting the implant in a joint in a first shape and changing the implant from a first shape to a second shape to conform to a shape a bone.Type: ApplicationFiled: September 23, 2019Publication date: January 16, 2020Inventors: David MYUNG, Michael J. JAASMA, Lampros KOURTIS, Jeffrey G. ROBERTS, Vernon HARTDEGEN
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Patent number: 10519270Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.Type: GrantFiled: August 3, 2017Date of Patent: December 31, 2019Assignee: Hyalex Orthopaedics, Inc.Inventors: Lampros Kourtis, David Myung, Daniel Chang, Bing Yu, Timothy Sun, Michael J. Jaasma, Vernon Hartdegen
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Patent number: 10457803Abstract: Orthopedic implants having a bone interface member and a water swellable IPN or semi-IPN with a stiffness, hydration, and/or compositional gradient from one side to the other and physically attached to the bone interface member. The invention also includes an orthopedic implant system including an implant that may conform to a bone surface and a joint capsule. The invention also includes orthopedic implants with water swellable IPN or semi-IPNs including a hydrophobic thermoset or thermoplastic polymer first network and an ionic polymer second network, joint capsules, labral components, and bone interface members. The invention also includes a method of inserting an orthopedic implant having a metal portion and a flexible polymer portion into a joint, including inserting the implant in a joint in a first shape and changing the implant from a first shape to a second shape to conform to a shape of a bone.Type: GrantFiled: December 29, 2016Date of Patent: October 29, 2019Assignee: Hyalex Orthopaedics, Inc.Inventors: David Myung, Michael J. Jaasma, Lampros Kourtis, Jeffrey G. Roberts, Vernon Hartdegen
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Publication number: 20190224367Abstract: IPN compositions and methods of making the same are provided. The IPN compositions can include a water swellable, water permeable IPN or semi-IPN member with a first polymer network including a hydrophobic thermoset or thermoplastic polymer, a second polymer network including a non-ionic polymer, and a third polymer network including an ionic polymer containing sulfonic acid functional groups that are otherwise difficult to form composites with hydrophobic polymers. The IPN compositions can be used in orthopedic implants or in mechanical applications as a bearing material.Type: ApplicationFiled: January 18, 2019Publication date: July 25, 2019Inventors: Lampros Kourtis, Iraklis Kourtis, Jun Li, Gary Li
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Publication number: 20190218386Abstract: The present disclosure pertains to ionic polymer compositions, including semi- and fully interpenetrating polymer networks, methods of making such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging for such articles.Type: ApplicationFiled: January 11, 2019Publication date: July 18, 2019Inventors: Iraklis Kourtis, Jun Li, Lampros Kourtis
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Publication number: 20190015211Abstract: An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.Type: ApplicationFiled: May 16, 2018Publication date: January 17, 2019Applicant: The Board of Trustees of The Leland Stanford Junior UniversityInventors: David MYUNG, Lampros KOURTIS, Laura HARTMANN, Curtis W. FRANK, Stuart B. GOODMAN, Dennis R. CARTER
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Publication number: 20180236136Abstract: IPN compositions and methods of making the same are provided. The IPN compositions can include a water swellable, water permeable IPN or semi-IPN member with a first polymer network including a hydrophobic thermoset or thermoplastic polymer, a second polymer network including a non-ionic polymer, and a third polymer network including an ionic polymer containing sulfonic acid functional groups that are otherwise difficult to form composites with hydrophobic polymers. The IPN compositions can be used in orthopedic implants or in mechanical applications as a bearing material.Type: ApplicationFiled: August 10, 2016Publication date: August 23, 2018Inventors: Lampros KOURTIS, David MYUNG, Iraklis KOURTIS
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Publication number: 20170348011Abstract: Described herein are methods and devices useful for reaming and shaping the surfaces of a joint in a mammalian body. The reaming and shaping devices and methods are particularly useful in preparation of a joint for a minimally invasive joint replacement or resurfacing, though they may be used as part of any appropriate arthroplasty procedure.Type: ApplicationFiled: February 24, 2017Publication date: December 7, 2017Inventors: Lampros Kourtis, David Myung, Michael J. Jaasma
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Publication number: 20170327624Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.Type: ApplicationFiled: August 3, 2017Publication date: November 16, 2017Inventors: Lampros KOURTIS, David MYUNG, Daniel CHANG, Bing YU, Timothy SUN, Michael J. JAASMA, Vernon HARTDEGEN
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Patent number: 9750842Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.Type: GrantFiled: October 7, 2015Date of Patent: September 5, 2017Assignee: HYALEX ORTHOPAEDICS, INC.Inventors: Lampros Kourtis, David Myung, Daniel Chang, Bing Yu, Timothy Sun, Michael J. Jaasma, Vernon Hartdegen
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Publication number: 20170107370Abstract: Orthopedic implants having a bone interface member and a water swellable IPN or semi-IPN with a stiffness, hydration, and/or compositional gradient from one side to the other and physically attached to the bone interface member. The invention also includes an orthopedic implant system including an implant that may conform to a bone surface and a joint capsule. The invention also includes orthopedic implants with water swellable IPN or semi-IPNs including a hydrophobic thermoset or thermoplastic polymer first network and an ionic polymer second network, joint capsules, labral components, and bone interface members. The invention also includes a method of inserting an orthopedic implant having a metal portion and a flexible polymer portion into a joint, including inserting the implant in a joint in a first shape and changing the implant from a first shape to a second shape to conform to a shape of a bone.Type: ApplicationFiled: December 29, 2016Publication date: April 20, 2017Inventors: David MYUNG, Michael J. JAASMA, Lampros KOURTIS, Jeffrey G. ROBERTS, Vernon HARTDEGEN
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Publication number: 20160346089Abstract: An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.Type: ApplicationFiled: July 8, 2016Publication date: December 1, 2016Inventors: David MYUNG, Lampros KOURTIS, Laura HARTMANN, Curtis W. FRANK, Stuart B. GOODMAN, Dennis R. CARTER
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Publication number: 20160256596Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.Type: ApplicationFiled: October 7, 2015Publication date: September 8, 2016Inventors: Lampros KOURTIS, David MYUNG, Daniel CHANG, Bing YU, Timothy SUN, Michael J. JAASMA, Vernon HARTDEGEN
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Patent number: 9387082Abstract: An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.Type: GrantFiled: February 24, 2014Date of Patent: July 12, 2016Assignees: The Board of Trustees of the Leland Stanford Junior University, The United States of America as Represented by the Department of Veterans AffairsInventors: David Myung, Lampros Kourtis, Laura Hartmann, Curtis W. Frank, Stuart B. Goodman, Dennis R. Carter
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Publication number: 20150284654Abstract: A composition of matter comprising a hydrophobic or hydrophilic (or both) interpenetrating polymer network containing a non-ionic/ionic polymer and a hydrophobic thermoset or thermoplastic polymer, articles made from such composition and methods of preparing such articles. The invention also includes a process for preparing a hydrophobic/hydrophilic IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an non-ionizable/ionizable monomer solution in contact with a hydrophobic thermoset or thermoplastic polymer; diffusing the monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the monomers to form a penetrating polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN.Type: ApplicationFiled: November 7, 2014Publication date: October 8, 2015Inventors: David MYUNG, Michael J. JAASMA, Lampros KOURTIS, Daniel CHANG, Curtis W. FRANK