Patents by Inventor Lan Chiang

Lan Chiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulin-like growth factor 1 receptors (IGF-1R) antisense oligonucleotide cells composition
    Patent number: 6071891
    Abstract: A composition and method for inhibiting the growth and metastasis of breast tumors, including a tumor immunogen derived from breast tumor cells treated with an antisense oligonucleotide complementary to a gene or mRNA for the receptor for insulin-like growth factor type 1.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: June 6, 2000
    Assignee: Regents of the University of Minnesota
    Inventors: Walter C. Low, Margaret A. Wallenfriedman, Lan Chiang
  • Antisense oligonucleotides and methods for treating central nervous system tumors
    Patent number: 5994320
    Abstract: The invention provides compositions and methods for treating primary brain cancer. The compositions include at least one antisense oligonucleotide that inhibits the proliferation of primary brain cancer cells. The antisense oligonucleotides are preferably complementary to and hybridize to a mRNA encoding c-myb. A method of the invention involves treating patients with primary brain cancer with a pharmaceutical composition including at least one antisense oligonucleotide in an amount effective to inhibit primary brain cell proliferation. The invention also provides probes and primers useful to identify primary brain cells having amplified and/or rearranged genes encoding c-myb.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: November 30, 1999
    Assignee: Regents of the University of Minnesota
    Inventors: Walter C. Low, Eric P. Flores, Walter A. Hall, Lan Chiang, John A. Conrad