Abstract: The present invention relates to a 3CL protease small-molecule inhibitor for treating or preventing a coronavirus infection, and the use thereof. Specifically, the present invention relates to a compound of formula (I) or an isotopically labeled compound thereof, or an optical isomer, a geometric isomer, a tautomer, or an isomer mixture thereof, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof, and the use thereof in the preparation of a drug for treating or preventing a coronavirus infection or a disease or symptom caused by a coronavirus.

Abstract: A control method is provided, applied to an electronic device. The electronic device includes a screen and a knob module. The control method includes: receiving a trigger signal to enable the knob module, and displaying an operating interface corresponding to the knob module on the screen according to the trigger signal, where the operating interface includes a plurality of functional regions that is arranged annularly, and the functional regions are configured to display a plurality of function options, where one of the functional regions shows a marked state; switching the functional region corresponding to the marked state according to a first input signal from the knob module; and selecting the functional region corresponding to the marked state according to a second input signal from the knob module.

Abstract: A control method is provided, applied to an electronic device. The electronic device includes a screen and a knob module. The control method includes: receiving a trigger signal to enable the knob module, and displaying an operating interface corresponding to the knob module on the screen according to the trigger signal, where the operating interface includes a plurality of functional regions that is arranged annularly, and the functional regions are configured to display a plurality of function options, where one of the functional regions shows a marked state; switching the functional region corresponding to the marked state according to a first input signal from the knob module; and selecting the functional region corresponding to the marked state according to a second input signal from the knob module.

Abstract: The present invention relates to a transition metal compound for an olefin polymerization catalyst, represented by chemical formula 1. The description of chemical formula 1 is as described in the specification.

Abstract: The present invention relates to a transition metal compound for an olefin polymerization catalyst, the transition metal compound being represented by chemical formula 1. The description of chemical formula 1 is as defined in the specification.

Abstract: The invention relates to: a hybrid supported metallocene catalyst includes at least one first metallocene compound among the compounds represented by chemical formula 1, at least one second metallocene compound among the compounds represented by chemical formula 2 and a cocatalyst compound; a method for preparing an ethylene-?-olefin copolymer, comprising polymerizing olefin monomers in the presence thereof; and an ethylene-?-olefin copolymer having improved melt strength.

Abstract: The present invention relates to a transition metal compound for an olefin polymerization catalyst, represented by chemical formula 1. The description of chemical formula 1 is as described in the specification.

Abstract: The present invention relates to a transition metal compound for an olefin polymerization catalyst, the transition metal compound being represented by chemical formula 1. The description of chemical formula 1 is as defined in the specification.

Abstract: A preparation method for a metallocene compound is provided. The method includes: stirring at least one compound I among compounds expressed by the following chemical formula (I) and a hydrogenation reaction catalyst of 0.10 to 0.55 parts by weight based on 100 parts by weight of the compound I under a hydrogen atmosphere; and obtaining a metallocene compound containing at least one first compound among the compounds expressed by the following chemical formula (1). Chemical formula (I) and (1) are provided in the specification.

Abstract: The invention relates to: a hybrid supported metallocene catalyst includes at least one first metallocene compound among the compounds represented by chemical formula 1, at least one second metallocene compound among the compounds represented by chemical formula 2 and a cocatalyst compound; a method for preparing an ethylene-?-olefin copolymer, comprising polymerizing olefin monomers in the presence thereof; and an ethylene-?-olefin copolymer having improved melt strength.

Abstract: A preparation method for a metallocene compound is provided. The method includes: stirring at least one compound I among compounds expressed by the following chemical formula (I) and a hydrogenation reaction catalyst of 0.10 to 0.55 parts by weight based on 100 parts by weight of the compound I under a hydrogen atmosphere; and obtaining a metallocene compound containing at least one first compound among the compounds expressed by the following chemical formula (1). Chemical formula (I) and (1) are provided in the specification.

Abstract: Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.

Abstract: Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.

Abstract: Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.

Abstract: Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.