Patents by Inventor Lan QU

Lan QU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrophilic linkers and ligand-drug conjugates thereof
    Patent number: 10646585
    Abstract: Hydrophilic linkers are useful for linking drugs to cell-binding ligands in ligand-drug conjugates, such as antibody-drug conjugates. The ligand-drug conjugate includes a cell-binding ligand capable of binding to a particular cell population, and a drug connected to the ligand by a hydrophilic linker. The hydrophilic linker includes one or more hydrophilic groups that render the linker hydrophilic. The hydrophilic linker may also include functional groups at the two termini for coupling to the drug and the cell-binding ligand respectively.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: May 12, 2020
    Assignee: HANGZHOU DAC BIOTECH CO., LTD.
    Inventors: Sanxing Sun, Robert Yongxin Zhao, Xing Li, Huihui Guo, Junxiang Jia, Hongsheng Xie, Xiaomai Zhou, Yuanyuan Huang, Qingliang Yang, Xiaotao Zhuo, Hangbo Ye, Shun Gai, Lan Qu, Wenjun Li, Chen Lin
  • Hydrophilic linkers and ligand-drug conjugates thereof
    Patent number: 10456479
    Abstract: Hydrophilic linkers are useful for linking drugs to cell-binding ligands in ligand-drug conjugates, such as antibody-drug conjugates. The ligand-drug conjugate includes a cell-binding ligand capable of binding to a particular cell population, and a drug connected to the ligand by a hydrophilic linker. The hydrophilic linker includes one or more hydrophilic groups that render the linker hydrophilic. The hydrophilic linker may also include functional groups at the two termini for coupling to the drug and the cell-binding ligand respectively.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: October 29, 2019
    Assignee: HANGZHOU DAC BIOTECH CO., LTD.
    Inventors: Sanxing Sun, Robert Yongxin Zhao, Xing Li, Huihui Guo, Junxiang Jia, Hongsheng Xie, Xiaomai Zhou, Yuanyuan Huang, Qingliang Yang, Xiaotao Zhuo, Hangbo Ye, Shun Gai, Lan Qu, Wenjun Li, Chen Lin
  • NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF
    Publication number: 20190125894
    Abstract: Hydrophilic linkers are useful for linking drugs to cell-binding ligands in ligand-drug conjugates, such as antibody-drug conjugates. The ligand-drug conjugate includes a cell-binding ligand capable of binding to a particular cell population, and a drug connected to the ligand by a hydrophilic linker. The hydrophilic linker includes one or more hydrophilic groups that render the linker hydrophilic. The hydrophilic linker may also include functional groups at the two termini for coupling to the drug and the cell-binding ligand respectively.
    Type: Application
    Filed: December 19, 2018
    Publication date: May 2, 2019
    Applicant: HANGZHOU DAC BIOTECH CO., LTD.
    Inventors: Sanxing SUN, Robert Yongxin ZHAO, Xing LI, Huihui GUO, Junxiang JIA, Hongsheng XIE, Xiaomai ZHOU, Yuanyuan HUANG, Qingliang YANG, Xiaotao ZHUO, Hangbo YE, Shun GAI, Lan QU, Wenjun LI, Chen LIN
  • NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF
    Publication number: 20180110876
    Abstract: Hydrophilic linkers are useful for linking drugs to cell-binding ligands in ligand-drug conjugates, such as antibody-drug conjugates. The ligand-drug conjugate includes a cell-binding ligand capable of binding to a particular cell population, and a drug connected to the ligand by a hydrophilic linker. The hydrophilic linker includes one or more hydrophilic groups that render the linker hydrophilic. The hydrophilic linker may also include functional groups at the two termini for coupling to the drug and the cell-binding ligand respectively.
    Type: Application
    Filed: March 19, 2015
    Publication date: April 26, 2018
    Applicant: HANGZHOU DAC BIOTECH CO., LTD.
    Inventors: Sanxing SUN, Robert Yongxin ZHAO, Xing LI, Huihui GUO, Junxiang JIA, Hongsheng XIE, Xiaomai ZHOU, Yuanyuan HUANG, Qingliang YANG, Xiaotao ZHUO, Hangbo YE, Shun GAI, Lan QU, Wenjun LI, Chen LIN
  • CAGE
    Publication number: 20100118440
    Abstract: A cage adapted to carry a plurality of disc drives and fix the disc drives within a case of a computer host is provided. The computer host has a mother board. The disc drives are spread horizontally within the cage, so that the disc drives are hung above the mother board.
    Type: Application
    Filed: December 29, 2008
    Publication date: May 13, 2010
    Applicant: INVENTEC CORPORATION
    Inventors: Fan-Lan Qu, Shi-Feng Wang, Tsai-Kuei Cheng