Patents by Inventor Lance Amate Larka

Lance Amate Larka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic reactors for oligonucleotide synthesis
    Patent number: 9707535
    Abstract: The present disclosure generally pertains to systems and methods for the chemical synthesis of micro-quantities of oligonucleotides or other chemical molecules. The system includes a reusable glass micro-reactor containing a paramagnetic solid support, a magnet, an electronic drive controller and an optical spectroscopy system capable of driving a plurality individual reactors. The system utilizes the electroosmotic movement of reactants through microfluidic channels. Spectrophotometric monitoring of the reaction products allows for the real-time determination of synthesis yield.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: July 18, 2017
    Assignee: The Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville
    Inventors: Lance Amate Larka, John D. Williams, Randy Gaillard
  • MICROFLUIDIC REACTORS FOR OLIGONUCLEOTIDE SYNTHESIS
    Publication number: 20150087820
    Abstract: The present disclosure generally pertains to systems and methods for the chemical synthesis of micro-quantities of oligonucleotides or other chemical molecules. The system includes a reusable glass micro-reactor containing a paramagnetic solid support, a magnet, an electronic drive controller and an optical spectroscopy system capable of driving a plurality individual reactors. The system utilizes the electroosmotic movement of reactants through microfluidic channels. Spectrophotometric monitoring of the reaction products allows for the real-time determination of synthesis yield.
    Type: Application
    Filed: July 17, 2014
    Publication date: March 26, 2015
    Inventors: Lance Amate Larka, John D. Williams, Randy Gaillard