Patents by Inventor Lance C. Held

Lance C. Held has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and apparatus for screening and detecting multiple genetic mutations
    Patent number: 8772467
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: July 8, 2014
    Assignee: Gamida for Life B.V.
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter
  • METHODS AND APPARATUS FOR SCREENING AND DETECTING MULTIPLE GENETIC MUTATIONS
    Publication number: 20100167960
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Application
    Filed: October 7, 2009
    Publication date: July 1, 2010
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter
  • Methods and apparatus for screening and detecting multiple genetic mutations
    Patent number: 7601493
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: October 13, 2009
    Assignee: Nanogen, Inc.
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter
  • Methods and apparatus for screening and detecting multiple genetic mutations
    Publication number: 20040146880
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Application
    Filed: July 24, 2003
    Publication date: July 29, 2004
    Applicant: Nanogen, Inc.
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter