Patents by Inventor Lance Fors

Lance Fors has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphism analysis by nucleic acid structure probing with structure-bridging oligonucleotides
    Patent number: 6210880
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: April 3, 2001
    Assignee: Third Wave Technologies, Inc.
    Inventors: Victor I. Lyamichev, Fang Dong, Mary Ann D. Brow, Lance Fors, Bruce P. Neri
  • Target-dependent reactions using structure-bridging oligonucleotides
    Patent number: 6194149
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: February 27, 2001
    Assignee: Third Wave Technologies, Inc.
    Inventors: Bruce Neri, Fang Dong, Victor Lyamichev, Mary Ann D. Brow, Lance Fors
  • Rapid detection of mutations in the p53 gene
    Patent number: 5843654
    Abstract: The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5' nucleases and 3' exonucleases, are used to screen for known and unknown mutations, including single base changes, in the human p53 gene. Methods are provided which allow for the identification of genetic mutations in the human p53 gene in a sample.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 1, 1998
    Assignee: Third Wave Technologies, Inc.
    Inventors: Laura M. Heisler, Lance Fors, Mary Ann D. Brow