Patents by Inventor Lance J. Stewart

Lance J. Stewart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of phosphorothiolate polynucleotides in ligating nucleic acids
    Patent number: 6951720
    Abstract: The invention provides a method of nonenzymatic ligation of a nucleic acid. The method consists of contacting a polynucleotide-3? phosphorothiolate with an acceptor polynucleotide under conditions that allow formation of a phosphodiester bond between the polynucleotide-3? phosphorothiolate and the acceptor polynucleotide. The invention also provides methods of molecular cloning. In one embodiment, the method consists of contacting an insert comprising a polynucleotide-3? phosphorothiolate with an acceptor vector under conditions that allow formation of a phosphodiester bond between the insert and the acceptor vector to generate a vector comprising an insert polynucleotide. The invention further provides a compound consisting of a polynucleotide-3? phosphorothiolate and a kit containing a polynucleotide-3? phosphorothiolate. Also provided is a method of ligating a nucleic acid using a non-sequence specific topoisomerase.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: October 4, 2005
    Assignees: San Diego State University Foundation, Emerald Biostructures, Incorporated
    Inventors: Alex B. Burgin, Jr., Lance J. Stewart
  • Method and a system for automating the execution of AMoRe over a heterogenous network of computers
    Publication number: 20040215398
    Abstract: This invention encompasses an apparatus for creating a database containing the results of distributed molecular replacement searches, which comprise data input system for inputting the results of distributed molecular replacement searches and related information and a database generator coupled to said data input system for receiving the results of distributed molecular replacement searches and related information and creating a database for storing the results of distributed molecular replacement searches and related information. The invention includes method of managing the invention of distributed molecular replacement searches.
    Type: Application
    Filed: October 11, 2002
    Publication date: October 28, 2004
    Applicant: Emerald Biostructures, Inc.
    Inventors: Mark B. Mixon, Michael Feese, Lance J. Stewart, Sridhar Prasad
  • Use of phosphorothiolate polynucleotides in ligating nucleic acids
    Publication number: 20030165841
    Abstract: The invention provides a method of nonenzymatic ligation of a nucleic acid. The method consists of contacting a polynucleotide-3′ phosphorothiolate with an acceptor polynucleotide under conditions that allow formation of a phosphodiester bond between the polynucleotide-3′ phosphorothiolate and the acceptor polynucleotide. The invention also provides methods of molecular cloning. In one embodiment, the method consists of contacting an insert comprising a polynucleotide-3′ phosphorothiolate with an acceptor vector under conditions that allow formation of a phosphodiester bond between the insert and the acceptor vector to generate a vector comprising an insert polynucleotide. The invention further provides a compound consisting of a polynucleotide-3′ phosphorothiolate and a kit containing a polynucleotide-3′ phosphorothiolate. Also provided is a method of ligating a nucleic acid using a non-sequence specific topoisomerase.
    Type: Application
    Filed: June 15, 2001
    Publication date: September 4, 2003
    Inventors: Alex B. Burgin, Lance J. Stewart