Patents by Inventor Lance Lepovitz

Lance Lepovitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for improving removal of ribosomal RNA from biological samples
    Patent number: 11401543
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: August 2, 2022
    Assignee: BIOO Scientific Corporation
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • Methods and Compositions for Improving Removal of Ribosomal RNA from Biological Samples
    Publication number: 20190330682
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Application
    Filed: June 13, 2019
    Publication date: October 31, 2019
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • Methods and compositions for improving removal of ribosomal RNA from biological samples
    Patent number: 10364455
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: July 30, 2019
    Assignee: BIOO Scientific Corporation
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • METHODS AND COMPOSITIONS FOR IMPROVING REMOVAL OF RIBOSOMAL RNA FROM BIOLOGICAL SAMPLES
    Publication number: 20140295418
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Application
    Filed: September 27, 2013
    Publication date: October 2, 2014
    Applicant: BIOO SCIENTIFIC CORPORATION
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue