Abstract: A device and method for activating platelet-rich plasma prior to injection. The device includes a lamp that has multiple LEDs for generating a desired light spectrum, such as red, blue, yellow, and green. The PPR is activated by exposure to polychromatic light generated by the lamp.

Abstract: Combined therapy for the treatment of osteoarthritis of the knee. The therapy includes administration of medium to high molecular weight hyaluronic acid intraarticular injections followed by administration of platelet-rich plasma also administered by intraarticular injections. Before administration of the hyaluronic acid intraarticular injections, the knee can be stretched and exercised using a static progressive knee stretch device. The knee can be supported by a single hinge knee brace that can be worn daily, and during weight-bearing activity.

Abstract: A PRP harvesting kit for harvesting platelet rich plasma that includes one or more collection tubes, each collection tube includes liquid biotin in an injectable form.

Abstract: A device for producing platelet-rich fibrin matrix (PRFM) from platelet-rich plasma (PRP) in a chemical-free manner. The device includes heating receptacles to receive one or more containers, such as syringes containing the PRP. PRP is to be added to the containers for converting it to PRFM. Uniform heat can be applied to the containers by the heating receptacles for triggering the thrombotic cascade in the PRP contained in the container. After heating for a pre-determined duration, immediately cooling the container by inserting the container in a cooling receptacle also provided in the device.