Patents by Inventor Lance Martin
Lance Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230349011Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: ApplicationFiled: April 20, 2023Publication date: November 2, 2023Inventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Khush, Mark Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Patent number: 11427876Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: GrantFiled: June 14, 2021Date of Patent: August 30, 2022Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Patent number: 11401562Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: GrantFiled: June 14, 2021Date of Patent: August 2, 2022Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Patent number: 11365453Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: GrantFiled: June 14, 2021Date of Patent: June 21, 2022Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Publication number: 20210310084Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: ApplicationFiled: June 14, 2021Publication date: October 7, 2021Inventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Publication number: 20210310085Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: ApplicationFiled: June 14, 2021Publication date: October 7, 2021Inventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Publication number: 20210301356Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: ApplicationFiled: June 14, 2021Publication date: September 30, 2021Inventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Patent number: 10768628Abstract: Systems and methods are directed to object detection at various ranges for autonomous vehicles. In one example, a system includes a camera providing a first field of view; a machine-learned model that has been trained to generate object detection range estimates based at least in part on labeled training data representing image data having a second field of view different from the first field of view; and a computing system including one or more processors; and memory including instructions that, when executed by the one or more processors, cause the one or more processors to perform operations. The operations include obtaining image data from the camera.Type: GrantFiled: May 30, 2018Date of Patent: September 8, 2020Assignee: UATC, LLCInventors: R. Lance Martin, Zac Vawter, Andrei Pokrovsky
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Publication number: 20200017926Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with an therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: ApplicationFiled: August 28, 2019Publication date: January 16, 2020Inventors: Iwijn de Vlaminck, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Patent number: 10450620Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with a therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: GrantFiled: November 7, 2014Date of Patent: October 22, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Iwijn de Vlaminick, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Publication number: 20190179327Abstract: Systems and methods are directed to object detection at various ranges for autonomous vehicles. In one example, a system includes a camera providing a first field of view; a machine-learned model that has been trained to generate object detection range estimates based at least in part on labeled training data representing image data having a second field of view different from the first field of view; and a computing system including one or more processors; and memory including instructions that, when executed by the one or more processors, cause the one or more processors to perform operations. The operations include obtaining image data from the camera.Type: ApplicationFiled: May 30, 2018Publication date: June 13, 2019Inventors: R. Lance Martin, Zac Vawter, Andrei Pokrovsky
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Patent number: 9783571Abstract: The disclosure provides a capture system and methods for isolating cysteine-containing peptides from biological fluid and proteolytic mixtures. The disclosure also provides compounds of formulae (II), (III), and (IV), useful in methods of the invention.Type: GrantFiled: April 5, 2012Date of Patent: October 10, 2017Inventor: Warham Lance Martin
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Publication number: 20160377635Abstract: The disclosure provides methods for processing a biological samples and determining the presence or an amount of a polypeptide in a biological sample, such as when the polypeptide is oxytocin or vasopressin.Type: ApplicationFiled: June 26, 2014Publication date: December 29, 2016Inventor: Warham Lance Martin, JR.
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Publication number: 20150158905Abstract: The disclosure provides a capture system and methods for isolating cysteine-containing peptides from biological fluid and proteolytic mixtures. The disclosure also provides compounds of formulae (II), (III), and (IV), useful in methods of the invention.Type: ApplicationFiled: April 5, 2012Publication date: June 11, 2015Inventor: Warham Lance Martin
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Publication number: 20150133391Abstract: Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with a therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like.Type: ApplicationFiled: November 7, 2014Publication date: May 14, 2015Inventors: Iwijn de Vlaminick, Michael Kertesz, Kiran Kaur Khush, Mark Alec Kowarsky, Lance Martin, Stephen R. Quake, Hannah Valantine
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Publication number: 20100285534Abstract: One aspect of the present invention relates to a method of processing lignocellulosic material, comprising initial steam pretreatment to give pretreated lignocellulosic material with an average particle size, followed by refining to give refined lignocellulosic material with an average particle size, wherein the average particle of the pretreated lignocellulosic material is greater than the average particle size of the refined lignocellulosic material. In certain embodiments, the lignocellulosic material is selected from the group consisting of grass, switch grass, cord grass, rye grass, reed canary grass, miscanthus, sugar-processing residues, sugar cane bagasse, agricultural wastes, rice straw, rice hulls, barley straw, corn cobs, cereal straw, wheat straw, canola straw, oat straw, oat hulls, corn fiber, stover, soybean stover, corn stover, forestry wastes, recycled wood pulp fiber, sawdust, hardwood, and softwood.Type: ApplicationFiled: April 18, 2008Publication date: November 11, 2010Applicant: MASCOMA CORPORATIONInventors: Colin R. South, Herve I. Garant, Richard Lance Martin
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Publication number: 20100279361Abstract: One aspect of the invention relates to a process, comprising treating lignocellulosic biomass according to a first pretreatment protocol, thereby generating a first product mixture; separating the first product mixture into a first plurality of fractions; and treating at least one fraction of said first plurality of fractions according to a second pretreatment protocol, thereby generating a second product mixture. In one embodiment, the lignocellulosic biomass is selected from the group consisting of grass, switch grass, cord grass, rye grass, reed canary grass, miscanthus, sugar-processing residues, sugarcane bagasse, agricultural wastes, rice straw, rice hulls, barley straw, corn cobs, cereal straw, wheat straw, canola straw, oat straw, oat hulls, corn fiber, stover, soybean stover, corn stover, forestry wastes, recycled wood pulp protocol protocol fiber, paper sludge, sawdust, hardwood, softwood, and combinations thereof.Type: ApplicationFiled: May 2, 2008Publication date: November 4, 2010Applicant: Mascoma CorporationInventors: Colin R. South, Charles E. Wyman, Richard Lance Martin
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Publication number: 20090131675Abstract: The invention provides methods and compositions for protein structure analysis, including substrate binding sites, sites of protein-protein interactions, three dimensional structure analysis, and stability, all with single amino acid resolution. In general, the subject methods involve introduction of cysteine residues, which serve as probes for physical analysis, into a protein by translational misincorporation in vivo. In many embodiments, proteins containing misincorporated cysteine residues are reacted with a crosslinking agent that covalently links misincorporated cysteine residues to a proximal amino acid in the folded protein. These methods, termed “MXLINK” methods, may be used for protein tertiary structure analysis. In other embodiments, cysteine-misincorporated proteins are used in protein footprinting methods, termed “MPAX” or “MSX” methods.Type: ApplicationFiled: September 24, 2007Publication date: May 21, 2009Inventors: Pehr A.B. Harbury, Joshua A. Silverman, Warham Lance Martin
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Patent number: 7288382Abstract: The invention provides methods and compositions for protein structure analysis, including substrate binding sites, sites of protein-protein interactions, three dimensional structure analysis, and stability, all with single amino acid resolution. In general, the subject methods involve introduction of cysteine residues, which serve as probes for physical analysis, into a protein by translational misincorporation in vivo. In many embodiments, proteins containing misincorporated cysteine residues are reacted with a crosslinking agent that covalently links misincorporated cysteine residues to a proximal amino acid in the folded protein. These methods, termed “MXLINK” methods, may be used for protein tertiary structure analysis. In other embodiments, cysteine-misincorporated proteins are used in protein footprinting methods, termed “MPAX” or “MSX” methods.Type: GrantFiled: March 14, 2003Date of Patent: October 30, 2007Assignee: The Board of Trustees od the Leland Stanford Junior UniversityInventors: Pehr A. B. Harbury, Joshua A. Silverman, Warham Lance Martin
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Publication number: 20030224448Abstract: The invention provides methods and compositions for protein structure analysis, including substrate binding sites, sites of protein-protein interactions, three dimensional structure analysis, and stability, all with single amino acid resolution. In general, the subject methods involve introduction of cysteine residues, which serve as probes for physical analysis, into a protein by translational misincorporation in vivo. In many embodiments, proteins containing misincorporated cysteine residues are reacted with a crosslinking agent that covalently links misincorporated cysteine residues to a proximal amino acid in the folded protein. These methods, termed “MXLINK” methods, may be used for protein tertiary structure analysis. In other embodiments, cysteine-misincorporated proteins are used in protein footprinting methods, termed “MPAX” or “MSX” methods.Type: ApplicationFiled: March 14, 2003Publication date: December 4, 2003Inventors: Pehr A. B. Harbury, Joshua A. Silverman, Warham Lance Martin