Abstract: An imaging system includes a housing assembly having a head unit configured to be at least partially directed towards a target site. An optical coherence tomography (OCT) module and a visualization module are located in the housing assembly and configured to respectively obtain OCT data and visualization data of the target site. The system includes a controller configured to generate a scanning pattern for a region of calibration selected in a calibration target. OCT data of the region of calibration is synchronously acquired. The controller is configured to obtain a projected two-dimensional OCT image of the region of calibration based on the OCT data, as an inverse mean-intensity projection. The controller is configured to register the projected two-dimensional OCT image to a corresponding view extracted from the visualization data, via a cascaded image registration process having a coarse registration stage and a fine registration stage.

Abstract: An imaging system includes a housing assembly having a head unit configured to be at least partially directed towards a target site. An optical coherence tomography (OCT) module and a visualization module are located in the housing assembly and configured to respectively obtain OCT data and visualization data of the target site. The system includes a controller configured to generate a scanning pattern for a region of calibration selected in a calibration target. OCT data of the region of calibration is synchronously acquired. The controller is configured to obtain a projected two-dimensional OCT image of the region of calibration based on the OCT data, as an inverse mean-intensity projection. The controller is configured to register the projected two-dimensional OCT image to a corresponding view extracted from the visualization data, via a cascaded image registration process having a coarse registration stage and a fine registration stage.

Abstract: Ophthalmic viewing systems for visualizing structures on and in an eye of a medical patient include an ophthalmic microscope, a gonioscopy device configured to work with the ophthalmic microscope to provide an image of an interior of the patient's eye, and a robotic arm configured to hold the gonioscopy device in a position in relation to the ophthalmic microscope and the patient's eye to provide the image of the eye's interior.

Abstract: A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.

Abstract: A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.

Abstract: A system and method for assisting a surgeon performing an ophthalmic procedure on an eye of a patient, the system including a lubrication assembly. The lubrication assembly may be disposed on a proximal end of a robotic arm, a proximal end of a surgical microscope, or a proximal end of a mobile stand or frame. Dispersal of lubricant from the lubrication assembly may be upon receipt of a direct input from a surgeon, according to a predetermined schedule, or according to an image processing protocol. The lubrication assembly may be moved into position over the eye of the patient manually by the surgeon or through the indirect command of a motion controller which is operable to move the robotic arm or the surgical microscope so as to extend the lubrication assembly into a desired position.

Abstract: A drug delivery device includes a drug delivery assembly configured to receive a portion of a head of a patient and mounted to a helmet or support. The drug delivery assembly includes one or more imaging devices configured to have an eye of the patient in a field of view thereof, an injection assembly configured to receive a drug to be injected, and a staging assembly including one or more actuators configured to position the injection assembly relative to the eye of the patient. A controller receives one or more images from the one or more imaging devices; detects a location of a limbus of the eye of the patient in the one or more images; and activate the one or more actuators to drive a needle into a placement location on the eye of the patient and dispense a drug into the eye through the needle.

Abstract: The present disclosure provides ophthalmic viewing systems for visualizing structures on and in an eye of a medical patient. Certain embodiments provide an ophthalmic viewing system including an ophthalmic microscope, a gonioscopy device configured to relay images of an interior periphery of a patient's eye to the ophthalmic microscope, and a robotic arm configured to hold the gonioscopy device in a position in relation to the ophthalmic microscope and the patient's eye to relay the images of the interior periphery of the patient's eye to the ophthalmic microscope for viewing by a user.

Abstract: A system includes a display device and an actuated structure mounted to the display device and configured to move the display device in three-dimensional space. The system includes an imaging device configured to capture images of a patient's eye during an ophthalmic surgery and display the images on the display device. A controller is configured to activate the actuated structure to maintain visibility of the display device to a surgeon performing the ophthalmic surgery. The display may be positioned based on a surgeon profile and/or a treatment plan. Whether the display is visible may be determined based on images from a camera mounted to the imaging device, the display device, or elsewhere. Whether the display is visible may be determined based on kinematic data for the actuated structure and/or a support for the imaging device.

Abstract: A system for assisting a surgeon performing intraocular surgery on an eye of a medical patient includes a robotic arm and a tool assembly at a working end of the robotic arm. The tool assembly can include a proximal end mounted to the robotic arm's working end, a distal end, and a narrow elongate support member extending between the tool assembly's proximal and distal ends. A motion controller is operable to move the robotic arm to extend the distal end and at least a portion of the support member through an incision site in a surface of the patient's eye, thereby to locate a visualization element at the distal end of the tool member at a position inside the patient's eye.

Abstract: An imaging system includes a housing assembly having a head unit configured to be at least partially directed towards a target site. An optical coherence tomography (OCT) module and a visualization module are located in the housing assembly and configured to respectively obtain OCT data and visualization data of the target site. The system includes a controller configured to generate a scanning pattern for a region of calibration selected in a calibration target. OCT data of the region of calibration is synchronously acquired. The controller is configured to obtain a projected two-dimensional OCT image of the region of calibration based on the OCT data, as an inverse mean-intensity projection. The controller is configured to register the projected two-dimensional OCT image to a corresponding view extracted from the visualization data, via a cascaded image registration process having a coarse registration stage and a fine registration stage.

Abstract: An apparatus and method of use are disclosed to automatically process and transfer fluids. The apparatus may include a user-interface, clamps, pumps, spinning membranes, pressure transducers, fluid detectors, solution towers, weight scales and tubing sets to control and monitor cell washing, concentrating and harvesting procedures. In addition, the apparatus may also be used to control and monitor a variety of fluid transfer procedures. The apparatus may also be used to execute default or user-defined cell washing and fluid transfer procedures.