Patents by Inventor Lance Stewart

Lance Stewart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210171928
    Abstract: Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO:1, are provided, wherein (a) the polypeptide degrades a PFQFQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456.
    Type: Application
    Filed: September 14, 2020
    Publication date: June 10, 2021
    Inventors: Ingrid Swanson PULTZ, Clancey WOLF, Justin Bloomfield SIEGEL, Christine Elaine TINBERG, Lance STEWART, David BAKER
  • Patent number: 10988748
    Abstract: Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO:1, are provided, wherein (a) the polypeptide degrades a PFQPQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: April 27, 2021
    Assignees: University of Washington, The Regents of the University of California
    Inventors: Ingrid Swanson Pultz, Clancey Wolf, Justin Bloomfield Siegel, Christine Elaine Tinberg, Lance Stewart, David Baker
  • Publication number: 20200397886
    Abstract: The present disclosure provides nanostructures and nanostructure-based vaccines. Some nanostructures of the present disclosure display antigens capable of eliciting immune responses to infectious agents such as bacteria, viruses, and pathogens. Some vaccines of the present disclosure are useful for preventing or decreasing the severity of infection with an infectious agent, including, for example and without limitation, lyme disease, pertussis, herpes virus, orthomyxovirus, paramyxovirus, pneumovirus, filovirus, flavivirus, reovirus, retrovirus, meningococcus, or malaria. The antigens may be attached to the core of the nanostructure either non-covalently or covalently, including as a fusion protein or by other means disclosed herein. Multimeric antigens may optionally be displayed along a symmetry axis of the nanostructure. Also provided are proteins and nucleic acid molecules encoding such proteins, vaccine compositions, and methods of administration.
    Type: Application
    Filed: February 28, 2019
    Publication date: December 24, 2020
    Inventors: Neil KING, David BAKER, Lance STEWART, Brooke FIALA, Daniel ELLIS, Lauren CARTER, Rashmi RAVICHANDRAN, George UEDA, Jorge FALLAS, Una NATTERMAN
  • Patent number: 10793846
    Abstract: Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO: 1, are provided, wherein (a) the polypeptide degrades a PFQPQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: October 6, 2020
    Assignees: University of Washington, The Regents of the University of California
    Inventors: Ingrid Swanson Pultz, Clancey Wolf, Justin Bloomfield Siegel, Christine Elaine Tinberg, Lance Stewart, David Baker
  • Publication number: 20200109387
    Abstract: Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO:1, are provided, wherein (a) the polypeptide degrades a PFQPQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456.
    Type: Application
    Filed: December 18, 2019
    Publication date: April 9, 2020
    Inventors: Ingrid Swanson PULTZ, Clancey WOLF, Justin Bloomfield SIEGEL, Christine Elaine TINBERG, Lance STEWART, David BAKER
  • Publication number: 20180142226
    Abstract: Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO: 1, are provided, wherein (a) the polypeptide degrades a PFQPQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456.
    Type: Application
    Filed: June 8, 2016
    Publication date: May 24, 2018
    Inventors: Ingrid Swanson PULTZ, Clancey WOLF, Justin Bloomfield SIEGEL, Christine Elaine TINBERG, Lance STEWART, David BAKER
  • Patent number: 7482166
    Abstract: A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: January 27, 2009
    Assignee: The Regents of the University of California
    Inventors: Peter Nollert, Lance Stewart, Hidong Kim
  • Patent number: 7410803
    Abstract: A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: August 12, 2008
    Assignee: The Regents of the University of California
    Inventors: Peter Nollert, Lance Stewart, Hidong Kim
  • Patent number: 7203683
    Abstract: This invention encompasses an apparatus for creating a database containing the results of distributed molecular replacement searches, which comprise data input system for inputting the results of distributed molecular replacement searches and related information and a database generator coupled to said data input system for receiving the results of distributed molecular replacement searches and related information and creating a database for storing the results of distributed molecular replacement searches and related information. The invention includes method of managing the invention of distributed molecular replacement searches.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: April 10, 2007
    Assignee: Emerald BioStructures, Inc.
    Inventors: Mark B. Mixon, Michael Feese, Lance Stewart, Sridhar Prasad
  • Publication number: 20050003502
    Abstract: This invention relates to crystalline structures of the topoisomerase I and their use in designing new anti-cancer agents anti-viral agents and anti-microbial agents.
    Type: Application
    Filed: November 14, 2001
    Publication date: January 6, 2005
    Applicant: Emerald BioStructures, Inc.
    Inventors: Alex Burgin, Kathyrn Hjerrild, Hidong Kim, Bart Staker, Lance Stewart, Craig Behnke, Michael Feese
  • Patent number: 6821487
    Abstract: A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: November 23, 2004
    Assignee: Regents of the University of California
    Inventors: Peter Nollert, Lance Stewart, Hidong Kim
  • Publication number: 20040096364
    Abstract: A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
    Type: Application
    Filed: October 17, 2003
    Publication date: May 20, 2004
    Applicant: Regents of the University of California
    Inventors: Peter Nollert, Lance Stewart, Hidong Kim
  • Publication number: 20040092034
    Abstract: A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
    Type: Application
    Filed: October 17, 2003
    Publication date: May 13, 2004
    Applicant: Regents of the University of California
    Inventors: Peter Nollert, Lance Stewart, Hidong Kim
  • Publication number: 20020072703
    Abstract: A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
    Type: Application
    Filed: July 18, 2001
    Publication date: June 13, 2002
    Inventors: Peter Nollert, Lance Stewart, Hidong Kim