Patents by Inventor Lance W. Farr

Lance W. Farr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9885769
    Abstract: A method of assessing a spatial frequency distribution within a sample comprising subjecting the sample to magnetic resonance excitation, receiving an echo signal from the sample while the sample is subjected to a magnetic field gradient, applying an invertible linear transform to the echo signal, identifying a region of interest in the transformed echo signal and deriving a corresponding window function, applying the window function (in the signal or transform domain) to the echo signal to remove echo signal coming from regions of the sample outside of the region of interest, and analyzing the one dimensional spatial frequency content in the windowed echo signal in order to access a one dimensional spatial frequency distribution within the region of interest within the sample without creating an image.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: February 6, 2018
    Assignee: Osteotronix Medical PTE Limited
    Inventors: David R. Chase, Timothy W. James, Lance W. Farr
  • Patent number: 9846211
    Abstract: In a structural analysis using NMR techniques, a method for gathering k-value data from frequency encoded spin echoes generated from internal volumes selectively excited by intersecting 90° and 180° slice selective and refocusing RF pulses and subjected to a read gradient for the purpose of quantifying the spatial frequency content of the selected internal volume without contamination by a FID signal, comprising: acquiring spin echo data such that the FID signal generated by imperfections in the 180° slice selective refocusing RF pulse is attenuated by the read gradient such that any remaining FID signal is spatially encoded with higher k-values than the frequency encoded k-values being recorded for subsequent structural analysis while simultaneously providing for t2 t2* and t1 contrast. Other aspects of the invention are disclosed.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: December 19, 2017
    Assignee: Osteotronix Medical PTE Limited
    Inventors: Timothy W. James, Lance W. Farr, James Rafferty, David Chase
  • Publication number: 20170199261
    Abstract: A method of improving the data quality in spatial frequency spectra by acquiring a prism acquisition consisting of echo data that is one or more repetitions of a one-dimensional frequency encoded signal along the length of one or more prism volumes, placed within a sample of a structure to be studied, generating prism profiles from the echo data, and correcting for motion during the acquisition by calculating motion having occurred during the prism acquisition from assessment of the prism profiles for the multiple repetitions, or by indicating a region of sample of structure to be studied on a reference image, using this to segment a map of features in the prism profiles and shifting the location of this region to correct for motion having occurred between the acquisition of the reference image and the prism acquisition.
    Type: Application
    Filed: May 30, 2015
    Publication date: July 13, 2017
    Inventors: Lance W. FARR, J. Michael BRADY, James RAFFERTY, Samantha Anne TELFER
  • Publication number: 20150153432
    Abstract: In a structural analysis using NMR techniques, a method for gathering k-value data from frequency encoded spin echoes generated from internal volumes selectively excited by intersecting 90° and 180° slice selective and refocusing RF pulses and subjected to a read gradient for the purpose of quantifying the spatial frequency content of the selected internal volume without contamination by a FID signal, comprising: acquiring spin echo data such that the FID signal generated by imperfections in the 180° slice selective refocusing RF pulse is attenuated by the read gradient such that any remaining FID signal is spatially encoded with higher k-values than the frequency encoded k-values being recorded for subsequent structural analysis while simultaneously providing for t2 t2* and t1 contrast. Other aspects of the invention are disclosed.
    Type: Application
    Filed: January 5, 2015
    Publication date: June 4, 2015
    Inventors: Timothy W. James, Lance W. Farr, James Rafferty, David Chase
  • Publication number: 20140303487
    Abstract: The disclosed invention is a method for detecting indications of the presence of Alzheimer's disease (AD) and related dementia-inducing, motor-control-related pathologies, and other diseases in the human brain using a magnetic-resonance based technique for measuring fine tissue and bone textures. Specifically, the invention focuses on refinements/adaptations to a prior art magnetic resonance fine texture measurement technique that facilitates/enables pushing the detection limits closer to the cellular level, so as to be able to measure the fine scale structures and tissue changes that are known to be characteristic of the neurodegenerative processes involved in the development of these diseases.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 9, 2014
    Inventors: Timothy W. James, Kristin James, Lance W. Farr, David R. Chase, J. Michael Brady, James Rafferty, John P. Heinrich
  • Publication number: 20140266200
    Abstract: A method of assessing a spatial frequency distribution within a sample comprising subjecting the sample to magnetic resonance excitation, receiving an echo signal from the sample while the sample is subjected to a magnetic field gradient, applying an invertible linear transform to the echo signal, identifying a region of interest in the transformed echo signal and deriving a corresponding window function, applying the window function (in the signal or transform domain) to the echo signal to remove echo signal coming from regions of the sample outside of the region of interest, and analyzing the one dimensional spatial frequency content in the windowed echo signal in order to access a one dimensional spatial frequency distribution within the region of interest within the sample without creating an image.
    Type: Application
    Filed: June 3, 2014
    Publication date: September 18, 2014
    Applicant: ACUITAS MEDICAL LIMITED
    Inventors: David R. Chase, Timothy W. James, Lance W. Farr
  • Publication number: 20140205541
    Abstract: The disclosed invention is a method for detecting indications of the presence of liver disease and other fibrotic diseases using a magnetic-resonance based technique for measuring fine tissue and bone textures. Specifically, the invention focuses on adaptations to this prior art to facilitate assessment of the presence and severity of liver disease, lung disease, and other fibrotic disease by measuring spatial wavelengths characteristic of the specific disease process across an areal cross-section through an organ. The results may be presented using a mapping technique. In this way, the resolution of MR is extended further than possible with current MR imaging, so as to be able to measure the fine scale structures and tissue changes that are known to be characteristic of the degenerative processes involved in the development of these diseases.
    Type: Application
    Filed: March 25, 2014
    Publication date: July 24, 2014
    Applicant: Acuitas Medical Limited
    Inventors: Timothy W. James, Samantha Telfer, Amanda Davies, Lance W. Farr, Ryan Pathak, Kristin James
  • Patent number: 8462346
    Abstract: A method for representing the structural information in a biological or physical sample is disclosed. In this method, a time-frequency representation of the spatial distribution within a sample is transformed into a color representation of the data. Furthermore, due to the directional sensitivity of the method for gathering the data, information about the structural anisotropy of the sample can also be encoded from the data. The application of this method to one or more regions within the sample enables a map to be generated which clearly illustrates quantitative measures of the structures present.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: June 11, 2013
    Assignee: Acuitas Medical Limited
    Inventors: Lance W. Farr, Timothy W. James, Jonathan N. Stearn
  • Publication number: 20120148126
    Abstract: A method for representing the structural information in a biological or physical sample is disclosed. In this method, a time-frequency representation of the spatial distribution within a sample is transformed into a color representation of the data. Furthermore, due to the directional sensitivity of the method for gathering the data, information about the structural anisotropy of the sample can also be encoded from the data. The application of this method to one or more regions within the sample enables a map to be generated which clearly illustrates quantitative measures of the structures present.
    Type: Application
    Filed: March 7, 2011
    Publication date: June 14, 2012
    Applicant: ACUITAS MEDICAL LIMITED
    Inventors: Lance W. Farr, Timothy W. James, Jonathan N. Stearn
  • Patent number: 7903251
    Abstract: A method for representing the structural information in a biological or physical sample is disclosed. In this method, a time-frequency representation of the spatial distribution within a sample is transformed into a color representation of the data. Furthermore, due to the directional sensitivity of the method for gathering the data, information about the structural anisotropy of the sample can also be encoded from the data. The application of this method to one or more regions within the sample enables a map to be generated which clearly illustrates quantitative measures of the structures present.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: March 8, 2011
    Assignee: Acuitas Medical Limited
    Inventors: Lance W. Farr, Timothy W. James, Jonathan N. Stearn