Patents by Inventor Landon H. Tompkins
Landon H. Tompkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11951000Abstract: An implant and method for repairing and/or replacing functionality of a native mitral valve are in various embodiments configured to reduce or eliminate mitral regurgitation and residual mitral valve leakage. A coiled anchor can be used to implant a prosthetic valve in a native mitral valve of a heart. The coiled anchor can include a plurality of ventricular turns and one or more atrial turns. The coiled anchor is configured to be implanted at the native mitral valve with the plurality of ventricular turns positioned in a left ventricle of the heart and around valve leaflets of the native mitral valve. The plurality of ventricular turns are configured such that when a radially outward pressure is applied to at least one of the plurality of ventricular turns, the coiled anchor is biased such that a first diameter of a first turn of the plurality of ventricular turns is expanded and a second diameter of a second turn of the plurality of ventricular turns is reduced.Type: GrantFiled: August 4, 2022Date of Patent: April 9, 2024Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11925553Abstract: Various systems, devices and methods associated with the placement of a dock or anchor for a prosthetic valve. The anchor can comprise a plurality of coils adapted to support a valve prosthesis, the plurality of coils including an upper coil, one or more middle coils, and a lower coil. The upper coil can have a larger diameter than the one or more middle coils and the lower coil, and the upper coil is configured to engage a wall of an atrium of the heart at a position superior to and spaced axially from the mitral valve annulus after the plurality of coils have been fully delivered from the coil guide catheter.Type: GrantFiled: November 8, 2021Date of Patent: March 12, 2024Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11918223Abstract: Disclosed are devices and methods for providing simple, fast, effective, and repeatable anastomotic graft connections, which can reduce (or eliminate) risks associated with graft anastomoses, thus improving patient outcomes. An example embodiment is an anastomotic graft connection device that includes a connector and a cuff. The connector includes a first flared end and a second flared end. The first flared end is configured to be inserted into a vessel (e.g., blood vessel). At least the second flared end is configured to be attached to a graft. The cuff includes an inner ring and an outer ring. The inner ring is configured to secure the graft to at least the second flared end of the connector, and the outer ring is configured to exert force on the vessel to seal the first flared end of the connector against an inner wall of the vessel.Type: GrantFiled: February 1, 2019Date of Patent: March 5, 2024Assignee: University of Louisville Research Foundation, Inc.Inventors: Landon H. Tompkins, Michael Sobieski, Steven Koenig, Gretel Monreal, Mark Slaughter
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Publication number: 20230414345Abstract: Anchors and systems for docking a prosthetic heart valve at a native heart valve are disclosed. An anchor can include at least three coils and a covering extending over at least a portion of the at least three coils. The covering comprises a fabric material and a foam underneath the fabric material.Type: ApplicationFiled: September 11, 2023Publication date: December 28, 2023Inventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11793630Abstract: Anchors and systems for docking a prosthetic heart valve at a native heart valve are disclosed. An anchor can include at least three coils and a seal positioned between at least two adjacent coils of the at least three coils. The seal circumscribes at least a portion of the at least two adjacent coils and has opposite ends that are spaced away from corresponding opposite ends of the at least three coils.Type: GrantFiled: March 10, 2021Date of Patent: October 24, 2023Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Publication number: 20230109200Abstract: An anchor for a prosthetic heart valve includes a core, a first cover layer, and a second cover layer. The core includes a plurality of helical turns. One or more outflow turns of the plurality of helical turns has a diameter configured to be disposed on an outflow side of a native valve, and one or more inflow turns of the plurality of helical turns has a diameter configured to be disposed on an inflow side of a native valve. The first cover layer is disposed over and contacts the helical core, and the first cover layer includes a first material. The second cover layer is disposed over and contacts the first cover layer, and the second cover layer includes a second material, which is different than the first material.Type: ApplicationFiled: December 9, 2022Publication date: April 6, 2023Inventors: Mark Chau, Alexander J. Siegel, Paul A. Spence, Landon H. Tompkins
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Patent number: 11523899Abstract: A coiled anchor is positioned at a mitral valve by extending and deflecting a catheter such that a distal end portion of the catheter has a curved shape that is disposed in a left atrium and a distal end of the catheter is positioned near a commissure of the mitral valve. A ventricular portion of the coiled anchor is advanced from the catheter under the mitral valve at the commissure and into a left ventricle. An atrial portion of the coiled anchor is deployed in the left atrium by retracting the catheter off the atrial portion of the coiled anchor while maintaining the position of the ventricular portion of the coiled anchor in the left ventricle.Type: GrantFiled: March 10, 2020Date of Patent: December 13, 2022Assignee: Mitral Valve Technologies SarlInventors: Mark Chau, Alexander J. Siegel, Paul A. Spence, Landon H. Tompkins
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Publication number: 20220378572Abstract: An implant and method for repairing and/or replacing functionality of a native mitral valve are in various embodiments configured to reduce or eliminate mitral regurgitation and residual mitral valve leakage. A coiled anchor can be used to implant a prosthetic valve in a native mitral valve of a heart. The coiled anchor can include a plurality of ventricular turns and one or more atrial turns. The coiled anchor is configured to be implanted at the native mitral valve with the plurality of ventricular turns positioned in a left ventricle of the heart and around valve leaflets of the native mitral valve. The plurality of ventricular turns are configured such that when a radially outward pressure is applied to at least one of the plurality of ventricular turns, the coiled anchor is biased such that a first diameter of a first turn of the plurality of ventricular turns is expanded and a second diameter of a second turn of the plurality of ventricular turns is reduced.Type: ApplicationFiled: August 4, 2022Publication date: December 1, 2022Inventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11406493Abstract: An implant and method for repairing and/or replacing functionality of a native mitral valve are in various embodiments configured to reduce or eliminate mitral regurgitation and residual mitral valve leakage. A coiled anchor can be used to implant a prosthetic valve in a native mitral valve of a heart. The coiled anchor can include a first turn, a second turn, and a third turn. The coiled anchor is configured to be implanted at the native mitral valve with the second turn and the third turn positioned in a left ventricle of the heart and around the valve leaflets of the native mitral valve. The first turn is positioned in a left atrium of the heart such that the first turn is spaced apart from the native mitral valve. The coiled anchor is configured for positioning such that the first turn is the sole turn of the coiled anchor positioned in the left atrium.Type: GrantFiled: May 18, 2020Date of Patent: August 9, 2022Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11376124Abstract: Various systems, devices and methods associated with the placement of a dock or anchor (72) for a prosthetic valve (120). The anchor (72) may take the form of a helical anchor having multiple coils (104, 108) and/or a stent-like structure. Various methods include different levels of minimal invasive procedures for delivering the prosthetic valve anchor (72) and prosthetic valve (120), as well as tissue anchors for plication or other purposes to the native valve position in the heart (14).Type: GrantFiled: March 4, 2019Date of Patent: July 5, 2022Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11304797Abstract: Methods for replacing a native heart valve. An anchor comprises coils adapted to support a heart valve prosthesis. The anchor is positioned at a native heart valve. An expansible heart valve prosthesis is delivered into the anchor and expanded inside the coils. This moves at least one coil from a first diameter to a second, larger diameter while securing the anchor and the heart valve prosthesis relative to each other. The heart valve prosthesis comprises a seal on the expansible heart valve prosthesis. Additional apparatus and methods are disclosed.Type: GrantFiled: February 5, 2019Date of Patent: April 19, 2022Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins, Mark Chau, Alexander J. Siegel
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Publication number: 20220110745Abstract: Methods and systems for replacing a native heart valve are disclosed. A system comprises a delivery catheter having a deflectable distal tip configured to bend in one or more directions relative to a native annulus of a native heart valve when the distal tip is positioned within an atrium of a heart and a helical anchor configured to be carried within the delivery catheter in a delivery configuration and to be axially movable relative to the deflectable distal tip. The helical anchor has a coiled configuration comprising a plurality of turns after being delivered from the deflectable distal tip into the heart, where the coiled configuration is configured to support a heart valve prosthesis.Type: ApplicationFiled: December 21, 2021Publication date: April 14, 2022Inventors: Paul A. Spence, Landon H. Tompkins, Mark Chau, Alexander J. Siegel
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Publication number: 20220054262Abstract: Various systems, devices and methods associated with the placement of a dock or anchor for a prosthetic valve. The anchor can comprise a plurality of coils adapted to support a valve prosthesis, the plurality of coils including an upper coil, one or more middle coils, and a lower coil. The upper coil can have a larger diameter than the one or more middle coils and the lower coil, and the upper coil is configured to engage a wall of an atrium of the heart at a position superior to and spaced axially from the mitral valve annulus after the plurality of coils have been fully delivered from the coil guide catheter.Type: ApplicationFiled: November 8, 2021Publication date: February 24, 2022Inventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11234811Abstract: Systems and methods for replacing a native heart valve. An anchor comprises multiple coils adapted to support a heart valve prosthesis. At least one of the coils is normally at a first diameter, and is expandable to a second, larger diameter upon application of radial outward force from within the anchor. An expansible heart valve prosthesis is provided and is configured to be delivered into the anchor and expanded inside the multiple coils. This moves at least one coil from the first diameter to the second diameter while securing the anchor and the heart valve prosthesis relative to each other. The system further includes a seal on the anchor that can prevent at least some blood leakage after implantation of the heart valve prosthesis in the helical anchor. Additional apparatus and methods are disclosed.Type: GrantFiled: February 5, 2019Date of Patent: February 1, 2022Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins, Mark Chau, Alexander J. Siegel
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Patent number: 11229515Abstract: Systems and methods comprising an anchor adapted to be positioned at a native heart valve annulus. The anchor comprises multiple coils adapted to support a heart valve prosthesis. A flexible outer tube adapted to hold the multiple coils of the anchor can combine with the anchor to form an assembly. A delivery tool adapted to deliver the assembly into position at a native heart valve can be provided and used. The outer tube is adapted to be removed from the multiple coils of the anchor after the coil portions of the anchor are positioned above and/or below the heart valve annulus. Additional apparatus and methods are disclosed.Type: GrantFiled: February 5, 2019Date of Patent: January 25, 2022Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 11166812Abstract: Various systems, devices and methods associated with the placement of a dock or anchor for a prosthetic valve. The anchor can take the form of an anchor having multiple coils. The distal end portion of the anchor can be spaced radially outwardly from the next adjacent coil to help direct the anchor around native leaflets of a native valve. Various methods include different procedures for delivering the anchor and prosthetic valve.Type: GrantFiled: March 4, 2019Date of Patent: November 9, 2021Assignee: Mitral Valve Technologies SariInventors: Paul A. Spence, Landon H. Tompkins
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Publication number: 20210186691Abstract: Anchors and systems for docking a prosthetic heart valve at a native heart valve are disclosed. An anchor can include at least three coils and a seal positioned between at least two adjacent coils of the at least three coils. The seal circumscribes at least a portion of the at least two adjacent coils and has opposite ends that are spaced away from corresponding opposite ends of the at least three coils.Type: ApplicationFiled: March 10, 2021Publication date: June 24, 2021Applicant: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Publication number: 20210137678Abstract: Prosthetic heart valves and anchors for use with such valves are provided that allow for an improved implantation procedure. In various embodiments, an anchoring device is formed as a coiled or twisted anchor that includes one or more turns that twist or curve around a central axis. One or more arms attached to the frame of the valve guide the anchoring device into position at the native valve as it exits the delivery catheter, and the expandable prosthetic valve is held within the coil of the anchoring device. The anchoring device and the valve can be delivered together, simplifying the valve replacement procedure.Type: ApplicationFiled: January 22, 2021Publication date: May 13, 2021Inventors: Paul A. Spence, Landon H. Tompkins
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Patent number: 10945837Abstract: Systems and methods for docking a heart valve prosthesis. A system can include an anchor formed as multiple coils adapted to support a heart valve prosthesis with coil portions positioned above and below the heart valve annulus. At least one of the coil portions can normally be at a first diameter and be expandable to a second, larger diameter upon application of radial outward force from within the helical anchor. Methods can include delivering an anchor, positioning and implanting a heart valve prosthesis, and expanding the heart valve prosthesis inside the anchor.Type: GrantFiled: May 30, 2018Date of Patent: March 16, 2021Assignee: Mitral Valve Technologies SarlInventors: Paul A. Spence, Landon H. Tompkins
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Publication number: 20210052272Abstract: Disclosed are devices and methods for providing simple, fast, effective, and repeatable anastomotic graft connections, which can reduce (or eliminate) risks associated with graft anastomoses, thus improving patient outcomes. An example embodiment is an anastomotic graft connection device that includes a connector and a cuff. The connector includes a first flared end and a second flared end. The first flared end is configured to be inserted into a vessel (e.g., blood vessel). At least the second flared end is configured to be attached to a graft. The cuff includes an inner ring and an outer ring. The inner ring is configured to secure the graft to at least the second flared end of the connector, and the outer ring is configured to exert force on the vessel to seal the first flared end of the connector against an inner wall of the vessel.Type: ApplicationFiled: February 1, 2019Publication date: February 25, 2021Inventors: Landon H. Tompkins, Michael Sobieski, Steven Koenig, Gretel Monreal, Mark Slaughter