Abstract: An integrated mounting pole system for communication and surveillance infrastructures includes a plurality of stackable sections, which are rotationally attached to a system cabinet of the system and one another. The sections include arms supporting antennas, video cameras, and other functional devices. A conduit and/or wiring raceway thereof coupling electronic equipment disposed in the system cabinet and the functional devices propagates through interior of the sections and the arms. The system may be disposed on a trailer and may include an autonomous source of electric power.

Abstract: An integrated mounting system for communication and surveillance infrastructures includes a gantry, a system cabinet, and an interconnecting conduit. The gantry includes a frame configured for housing functional devices (e.g., antennas, video cameras, sensors, photovoltaic panels, and the like) and supporting posts. The system cabinet contains electronic equipment of the functional devices and provides connectivity to land data networks and external sources of power. The system may be installed on a trailer and include autonomous sources of power.

Abstract: An integrated mounting pole system for communication and surveillance infrastructures includes a plurality of stackable sections, which are rotationally attached to a system cabinet of the system and one another. The sections include arms supporting antennas, video cameras, and other functional devices. A conduit and/or wiring raceway thereof coupling electronic equipment disposed in the system cabinet and the functional devices propagates through interior of the sections and the arms. The system may be disposed on a trailer and may include an autonomous source of electric power.

Abstract: An integrated mounting system for communication and surveillance infrastructures includes a gantry, a system cabinet, and an interconnecting conduit. The gantry includes a frame configured for housing functional devices (e.g., antennas, video cameras, sensors, photovoltaic panels, and the like) and supporting posts. The system cabinet contains electronic equipment of the functional devices and provides connectivity to land data networks and external sources of power. The system may be installed on a trailer and include autonomous sources of power.

Abstract: According to the present invention, there is disclosed a system and method for actively and passively detecting and analyzing neurological damage in an injured person using electrical and chemical analyses supported by a computer system and database, selecting an appropriate neurologically protective pharmaceutical for that injury type and circumstances based on the result of said analyses, and then delivering this pharmaceutical via direct injection, intravenous delivery, or other means into the person using components of the kit of which all the elements of the invention are a part.

Abstract: A system and method of automatic access and control management of databases within a system includes a data management computer system and interconnected local computer systems. An accessing system requests information from a target system by data management system. The database management determines whether or not the information request satisfies a predetermined shared information access stored in a lookup table. The data management system verifies the transmitted information by comparing it to the rule and redacts information if necessary and transmits the verified information to the accessing local computer system. The data management system rejects the information access request if determined that the predetermined rule is not satisfied. The data management system determines whether to update the predetermined rule if access is nondeterminable, and automatically updates the rule. The accessing computer system uses the verified information.

Abstract: A therapeutic composition includes a salicylate administering concert with at least one salicylate excretion compound of a glycine salicylate conjugate and a gluconoride salicylate conjugate. A therapeutic composition is provided that has an extended excretion half-life for a salicylate that includes the administration of the salicylate in concert with an enzymatic substrate competitor. The enzymatic substrate competitor being competitive with salicylate or gluconoride. Salicylate enzymatic substrate competitors include benzoate or other aromatic derivatives, while gluconoride enzymatic substrate competitors include an active phenolic unit. A process for treating a human or non-human subject includes administering to a subject a therapeutically effective amount of a salicylate and a salicylate pharmacokinetics modifier of glycine salicylate conjugate, gluconoride salicylate conjugate, benzoate, an aromatic derivative and an active phenolic unit, along with a pharmaceutically acceptable carrier.

Abstract: A system and method of active neuro-protection for detecting and arresting injury to an individual is provided. The system includes a sensing means for sensing the occurrence of a predetermined event within an environment and for operatively transmitting an event indicating signal. The system also includes a controller operatively in communication with the sensing means including a processor for processing the event indicating signal to determine if a predetermined condition is met for releasing a neuro-protective agent. The system further includes a dispensing means for releasing the neuro-protective drug, and the dispensing means is operatively in communication with the controller, and releases the neuro-protective drug if the controller transmits a drug releasing signal to the dispensing means if the predetermined condition is met.

Abstract: A complex is provided for the treatment of neurogenic conditions having the formula: where R1 is M is a metal ion Ca(II), Mg(II), Cu(II) or Ni(II); n is an integer 1 or 2; R is BBB peptide, transferrin, membrane transporter peptide, TAT peptide, bradykinin, beta-endorphin, bombesin, calcitonin, cholecystokinin, an enkephalin, dynorphin, insulin, gastrin, substance P, neurotensin, glucagon, secretin, somatostatin, motilin, vasopressin, oxytocin, prolactin, thyrotropin, an angiotensin, galanin, neuropeptide Y, thyrotropin-releasing hormone, gonadotropnin-releasing hormone, growth hormone-releasing hormone, luteinizing hormone, vasoactive intestinal peptidegluconate, L-lactate, L-leucine, L-tryptophan, and L-glutamate; and R is coupled to M through a carboxylate moiety. Magnesium (II) represents the preferred metal ion as magnesium is known to have neuroprotective effects.

Abstract: A compound of the formula where R1 is H, C1-C4 alkyl and OH; R2 in is H, C1-C4 alkyl and OH; R3 is H and C1-C4 alkyl; R4 is H and C1-C4 alkyl; n is an integer between 0 and 2 inclusive; R5 is a nullity, NHR7C(O)—, C6H4—, C6H4—O—; R7 is C2-C6 alkyl; and R6 is a moiety capable of crossing the blood brain barrier and is as a free compound serotonin, dopamine, blood brain barrier (BBB) peptide, membrane translocating peptide, TAT peptides, bradykinin, beta-endorphin, bombesin, calcitonin, cholecystokinin, an enkephalin, dynorphin, insulin, gastrin, substance P, neurotensin, glucagon, secretin, somatostatin, motilin, vasopressin, oxytocin, prolactin, thyrotropin, an angiotensin, galanin, neuropeptide Y, thyrotropin-releasing hormone, gonadotropnin-releasing hormone, growth hormone-releasing hormone, luteinizing hormone, vasoactive intestinal peptidegluconate, transferrin, glucosylamine, amino saccharin, saccharin ester, lactylamine, leucine, tryptophan, amino glutamate and amino cholines.

Abstract: A composition is provided having the formula where R1 and R2 are each independently H or a C1-C4 hydrocarbon; R3 is H, and R4 is a moiety capable of crossing the blood brain barrier selected from the group consisting of: an amino acid, a peptide, transferrin, gluconate, lactate, citrate, malate, fumarate, benzoate, salicylate, pyruvate and propionate. The composition includes 4-aminopyridine and a transporter species which allows for improved transport of the aminopyridine across the blood brain barrier thereby reducing systemic side effects of aminopyridine administration.

Abstract: A compound is provided that has the formula NH2CH2CH2CH2C(O)N—R ??(I) where R is a moiety capable of crossing the blood brain barrier and is as a free compound serotonin, dopamine blood brain barrier (BBB) peptide, membrane translocating protein, TAT peptides, bradykinin, beta-endorphin, bombesin, calcitonin, cholecystokinin, an enkephalin, dynorphin, insulin, gastrin, substance P, neurotensin, glucagon, secretin, somatostatin, motilin, vasopressin, oxytocin, prolactin, thyrotropin, an angiotensin, galanin, neuropeptide Y, thyrotropin-releasing hormone, gonadotropnin-releasing hormone, growth hormone-releasing hormone, luteinizing hormone, vasoactive intestinal peptidetransferrin, glucosylamnine, amino saccharin, lactylamine, leucine, tryptophan, glutamate and amino cholines.

Abstract: A compound provided by the present invention includes an endocannabinoid, endocannabinoid derivative, or endocannabinoid analog moiety covalently bonded to a biologically active peptide. One example of an inventive compound described is a conjugate of an endocannabinoid, endocannabinoid derivative, or endocannabinoid analog moiety covalently coupled to an opioid peptide, such as an endorphin, enkephalin, dynorphin or endomorphin. Also detailed are processes for making the described conjugates and pharmaceutical compositions including such compounds.

Abstract: A compound is provided that has the formula NH2CH2CH2CHR1C(O)N—R??(I) where R1 is p-chlorophenyl, R is a moiety capable of crossing the blood brain barrier and is as a free compound serotonin, dopamine blood brain barrier (BBB) peptide, membrane translocating protein, TAT peptides, bradykinin, beta-endorphin, bombesin, calcitonin, cholecystokinin, an enkephalin, dynorphin, insulin, gastrin, substance P, neurotensin, glucagon, secretin, somatostatin, motilin, vasopressin, oxytocin, prolactin, thyrotropin, an angiotensin, galanin, neuropeptide Y, thyrotropin-releasing hormone, gonadotropnin-releasing hormone, growth hormone-releasing hormone, luteinizing hormone, vasoactive intestinal peptide transferrin, glucosylamine, amino saccharin, lactylamine, leucine, tryptophan, glutamate and amino cholines.

Abstract: A therapeutic agent delivery pump includes a bottle having a pressurant chamber containing a pressurant and a therapeutic agent volume, the volume terminating in a visco-elastic septum. The bottle has a piercing element in alignment with the septum and in fluid communication with tubing. A flow restriction gauge impinges on the tubing to restrict the flow of a therapeutic agent from the balloon. An intrathecal drug delivery system includes a pump as described above, along with a pressure compatible catheter. A connector is provided between the pump and the catheter. An externally disposed therapeutic pump assembly for administering a therapeutic delivery agent in metered fashion to an internal location of a patient includes a three-dimensional body, with a lid secured to the body. A bag holding a volume of therapeutic delivery agent contained within the body in order to progressively compress.

Abstract: A system and method of capturing and managing the medical information obtained during an imaging procedure is provided. The system includes a sonogram imaging device operated by a technician, and a technician computer system in communication with the imaging device via a communications network. A computer server communicates with the technician computer system, and includes a medical diagnostic imaging software program. A healthcare provider computer system is operatively in communication with the computer server via the communications network. The method includes the steps of conducting the imaging procedure and building a study from the generated image and captured impression of the real-time observations of the generated image and measurement data by the technician. The study is stored in the database associated with a computer server and is accessible by a healthcare professional using a healthcare provider computer system for preparing a medical diagnosis.