Patents by Inventor Lane A. Clizbe

Lane A. Clizbe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional zwitterionic polymer conjugates
    Patent number: 11819531
    Abstract: The present invention provides random copolymers containing zwitterions and one or more functional agents, and methods of preparing such random copolymers.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: November 21, 2023
    Assignee: Kodiak Sciences Inc.
    Inventors: Stephen A. Charles, D. Victor Perlroth, Lane A. Clizbe, Didier G. Benoit, Wayne To
  • MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES
    Publication number: 20230277616
    Abstract: The present invention provides random copolymers containing zwitterions and one or more functional agents, and methods of preparing such random copolymers.
    Type: Application
    Filed: April 14, 2016
    Publication date: September 7, 2023
    Inventors: Stephen A. Charles, D. Victor Perlroth, Lane A. Clizbe, Didier G. Benoit, Wayne To
  • HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS
    Publication number: 20210402015
    Abstract: The present invention provides multi-armed high MW polymers containing hydrophilic groups and one or more functional agents, and methods of preparing such polymers.
    Type: Application
    Filed: August 23, 2021
    Publication date: December 30, 2021
    Inventors: Stephen A. CHARLES, Daniel Victor PERLROTH, Didier G. BENOIT, Lane A. CLIZBE, Wayne TO, Linda J. ZADIK, Jeanne M. PRATT
  • HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS
    Publication number: 20200171179
    Abstract: The present invention provides multi-armed high MW polymers containing hydrophilic groups and one or more functional agents, and methods of preparing such polymers.
    Type: Application
    Filed: January 31, 2020
    Publication date: June 4, 2020
    Inventors: Stephen A. Charles, D. Victor Perlroth, Didier G. Benoit, Lane A. Clizbe, Wayne To, Linda J. Zadik, Jeanne M. Pratt
  • HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS
    Publication number: 20170143841
    Abstract: The present invention provides multi-armed high MW polymers containing hydrophilic groups and one or more functional agents, and methods of preparing such polymers.
    Type: Application
    Filed: December 2, 2016
    Publication date: May 25, 2017
    Inventors: Stephen A. Charles, D. Victor Perlroth, Didier G. Benoit, Lane A. Clizbe, Wayne To, Linda J. Zadik, Jeanne M. Pratt
  • MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES
    Publication number: 20160287715
    Abstract: The present invention provides random copolymers containing zwitterions and one or more functional agents, and methods of preparing such random copolymers.
    Type: Application
    Filed: April 14, 2016
    Publication date: October 6, 2016
    Inventors: Stephen A. Charles, D. Victor Perlroth, Lane A. Clizbe, Didier G. Benoit, Wayne To
  • HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS
    Publication number: 20140024776
    Abstract: The present invention provides multi-armed high MW polymers containing hydrophilic groups and one or more functional agents, and methods of preparing such polymers.
    Type: Application
    Filed: May 23, 2013
    Publication date: January 23, 2014
    Applicant: Oligasis
    Inventors: Stephen A. Charles, Victor D. Perlroth, Didier G. Benoit, Lane A. Clizbe, Wayne To, Linda J. Zadik, Jeanne M. Pratt
  • MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES
    Publication number: 20130045522
    Abstract: The present invention provides random copolymers containing zwitterions and one or more functional agents, and methods of preparing such random copolymers.
    Type: Application
    Filed: December 20, 2010
    Publication date: February 21, 2013
    Applicant: Oligasis
    Inventors: Stephen A. Charles, D. Victor Perlroth, Lane A. Clizbe, Didier G. Benoit, Wayne To
  • Coatings for capillaries capable of capturing analytes
    Publication number: 20080017512
    Abstract: In general, the present invention provides microfluidic devices comprised of polymer coatings with triggerable analyte capture moieties. In some embodiments, a microfluidic device is provided, useful in electrophoresis, and is comprised of at least one separation channel with a surface, such as but not necessarily an inner surface, and having a polymer coating introduced onto the surface. The polymer coating is comprised of moieties capable of being triggered to immobilize analytes to the surface.
    Type: Application
    Filed: January 16, 2007
    Publication date: January 24, 2008
    Inventors: Andrei V. Bordunov, Karl O. Voss, Lane A. Clizbe, Roger A. O'Neill
  • Inhibitors of factor Xa
    Patent number: 6534535
    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds of formula (I) below: are useful in vitro or in vivo for preventing or treating coagulation disorders.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: March 18, 2003
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Bing-Yan Zhu, Robert M. Scarborough, Lane Clizbe, Brandon Doughan, Zhaozhong Jon Jia, Kim Kane-Maguire, Charles Marlowe, Yonghong Song, Ting Su, Willy Teng, Penglie Zhang
  • Inhibitors of factor Xa
    Patent number: 6399627
    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: June 4, 2002
    Assignee: Cor Therapeutics, Inc.
    Inventors: Yonghong Song, Bing-Yan Zhu, Robert M. Scarborough, Lane Clizbe, Zhaozhong Jon Jia, Ting Su, Willy Teng
  • Alkenyl acetamides
    Patent number: 4665228
    Abstract: Compounds of the formula: ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3 are independently hydrogen, halogen, C.sub.1-6 alkyl, or haloalkyl; R.sub.4 is hydrogen; C.sub.1-4 alkyl, alkenyl, alkoxy, haloalkyl; C.sub.1-2 alkylamino, C.sub.1-2 alkylthio, C.sub.2-4 cycloalkyl, C.sub.2-6 alkoxyalkyl, C.sub.2-6 alkylthiomethyl, amino, phenoxy, phenamino, or furan; and R.sub.5 is hydrogen or C.sub.1-4 alkyl, are useful to retard the growth of turf grass.
    Type: Grant
    Filed: April 4, 1986
    Date of Patent: May 12, 1987
    Assignee: Monsanto Company
    Inventors: Gerhard H. Alt, John P. Chupp, Lane A. Clizbe
  • Novel alkenyl acetamides and their use in the regulation of the natural growth or development of turf grass
    Patent number: 4618357
    Abstract: The growth of turf grass can be retarded by applying to said turf grass an effective growth retarding amount of a compound of the formula: ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3 are independently hydrogen, halogen, C.sub.1-6 alkyl, or haloalkyl; R.sub.4 is hydrogen; C.sub.1-4 alkyl, alkenyl, alkoxy, haloalkyl; C.sub.1-2 alkylamino, C.sub.1-2 alkylthio, C.sub.2-4 cycloalkyl, C.sub.2-6 alkoxyalkyl, C.sub.2-6 alkylthiomethyl, amino, phenoxy, phenamino, or furan; and R.sub.5 is hydrogen or C.sub.1-4 alkyl.
    Type: Grant
    Filed: February 13, 1985
    Date of Patent: October 21, 1986
    Assignee: Monsanto Company
    Inventors: Gerhard H. Alt, John P. Chupp, Lane A. Clizbe