Patents by Inventor Lanfranco Callegaro

Lanfranco Callegaro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11203649
    Abstract: The present invention discloses a functionalized hyaluronic acid or a derivative thereof, as well as a process for the preparation thereof, and the use thereof as a biomaterial and as an ingredient in pharmaceutical compositions. The present invention furthermore discloses the use of said functionalized hyaluronic acid or a derivative thereof in the treatment of pathologies ascribable to altered galectin expression.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: December 21, 2021
    Assignee: JOINTHERAPEUTICS S.R.L.
    Inventors: Giulio Bianchini, Lanfranco Callegaro
  • Patent number: 11155647
    Abstract: A neutral salt consisting of a polyaminosaccharide cation and an anion, as well as a procedure for the preparation of the neutral salt and uses thereof as a biomaterial and as an ingredient in pharmaceutical compositions are disclosed. Indeed, said neutral salt has surprisingly exhibited high water-solubility and high purity, the preparation procedure having minimised the content of high-risk contaminants in the final product and reduced reaction and purification times.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: October 26, 2021
    Assignee: JOINTHERAPEUTICS S.R.L.
    Inventors: Giulio Bianchini, Lanfranco Callegaro
  • Patent number: 11116787
    Abstract: The present application describes polysaccharide compositions that can be used as modulators of cell proliferation processes and their use in tissue repair with fibrotic process inhibition. These modulation properties can be usefully used in tissue repair for the prevention of fibrotic processes and/or tissue adhesions in traumatic, post-surgical and chronic fibrotic processes associated to autoimmune diseases.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: September 14, 2021
    Assignee: JOINTHERAPEUTICS S.R.L.
    Inventors: Lanfranco Callegaro, Paola Brun, Giulio Bianchini
  • Publication number: 20210189017
    Abstract: The present invention discloses a functionalized hyaluronic acid or a derivative thereof, as well as a process for the preparation thereof, and the use thereof as a biomaterial and as an ingredient in pharmaceutical compositions. The present invention furthermore discloses the use of said functionalized hyaluronic acid or a derivative thereof in the treatment of pathologies ascribable to altered galectin expression.
    Type: Application
    Filed: October 24, 2018
    Publication date: June 24, 2021
    Applicant: JOINTHERAPEUTICS S.R.L.
    Inventors: Giulio Bianchini, Lanfranco Callegaro
  • Patent number: 11040089
    Abstract: The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase (and relative pharmaceutical formulations) for the preparation of a dressing for topical treatment of various kinds of wounds, burns of varying depth, pressure sores, vascular ulcers and diabetic foot ulcers as well as for the treatment of hypertrophic and keloid scars.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: June 22, 2021
    Assignee: FIDIA FARMACEUTICI S.P.A
    Inventors: Susanna Vaccaro, Giovanni Gennari, Lanfranco Callegaro, Antonio Giannelli, Salvatore Caruso
  • Publication number: 20200407468
    Abstract: A neutral salt consisting of a polyaminosaccharide cation and an anion, as well as a procedure for the preparation of the neutral salt and uses thereof as a biomaterial and as an ingredient in pharmaceutical compositions are disclosed. Indeed, said neutral salt has surprisingly exhibited high water-solubility and high purity, the preparation procedure having minimised the content of high-risk contaminants in the final product and reduced reaction and purification times.
    Type: Application
    Filed: May 29, 2018
    Publication date: December 31, 2020
    Applicant: JOINTHERAPEUTICS S.R.L.
    Inventors: Giulio Bianchini, Lanfranco Callegaro
  • Publication number: 20200306288
    Abstract: The present application describes polysaccharide compositions that can be used as modulators of cell proliferation processes and their use in tissue repair with fibrotic process inhibition. These modulation properties can be usefully used in tissue repair for the prevention of fibrotic processes and/or tissue adhesions in traumatic, post-surgical and chronic fibrotic processes associated to autoimmune diseases.
    Type: Application
    Filed: June 6, 2017
    Publication date: October 1, 2020
    Applicant: JOINTHERAPEUTICS S.R.L.
    Inventors: Lanfranco Callegaro, Paola BRUN, Giulio Bianchini
  • Publication number: 20200297755
    Abstract: The present invention discloses a pharmaceutical composition comprising at least one bioactive substance and at least one neutral salt consisting of a polyamino-saccharide cation and an anion, for use in the treatment of articular tissues affected by arthropathies, wherein said pharmaceutical composition reduces expression of the key receptors involved in the genesis the inflammatory cascade and efficaciously maintains performance for a prolonged period of time.
    Type: Application
    Filed: October 3, 2018
    Publication date: September 24, 2020
    Applicant: JOINTHERAPEUTICS S.R.L.
    Inventors: Giulio Bianchini, Lanfranco Callegaro
  • Publication number: 20190160183
    Abstract: The present application describes compositions that can be used for the controlled release of pharmacological active ingredients from a viscoelastic aqueous polysaccharide matrix, and their potential use in the treatment of different stages of musculoskeletal diseases. The combination of drug release modulation and the viscoelastic nature of the composition makes possible the use thereof in the treatment of acute and chronic phases of musculoskeletal diseases characterized by an inflammatory state, and where a therapeutic effect and a viscosupplemental contribution are required.
    Type: Application
    Filed: July 18, 2017
    Publication date: May 30, 2019
    Applicant: JOINTHERAPEUTICS S.R.L.
    Inventors: Margherita Morpurgo, Giulio Bianchini, Lanfranco Callegaro
  • Publication number: 20170209552
    Abstract: The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase (and relative pharmaceutical formulations) for the preparation of a dressing for topical treatment of various kinds of wounds, burns of varying depth, pressure sores, vascular ulcers and diabetic foot ulcers as well as for the treatment of hypertrophic and keloid scars.
    Type: Application
    Filed: February 2, 2017
    Publication date: July 27, 2017
    Applicant: Fidia Farmaceutici S.p.A.
    Inventors: Susanna VACCARO, Giovanni GENNARI, Lanfranco CALLEGARO, Antonio GIANNELLI, Salvatore CARUSO
  • Patent number: 9603910
    Abstract: The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase (and relative pharmaceutical formulations) for the preparation of a dressing for topical treatment of various kinds of wounds, burns of varying depth, pressure sores, vascular ulcers and diabetic foot ulcers as well as for the treatment of hypertrophic and keloid scars.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: March 28, 2017
    Assignee: FIDIA FARMACEUTICI S.p.A.
    Inventors: Susanna Vaccaro, Giovanni Gennari, Lanfranco Callegaro, Antonio Giannelli, Salvatore Caruso
  • Patent number: 9295690
    Abstract: This invention relates to oral and intra-articular formulations based on sulphated hyaluronic acid which are effective in the treatment of degenerative osteoarthritis.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 29, 2016
    Assignee: FIDIA FARMACEUTICI S.p.A.
    Inventors: Lanfranco Callegaro, Davide Renier
  • Publication number: 20140377249
    Abstract: The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase (and relative pharmaceutical formulations) for the preparation of a dressing for topical treatment of various kinds of wounds, burns of varying depth, pressure sores, vascular ulcers and diabetic foot ulcers as well as for the treatment of hypertrophic and keloid scars.
    Type: Application
    Filed: September 9, 2014
    Publication date: December 25, 2014
    Applicant: FIDIA FARMACEUTICI S.P.A.
    Inventors: Susanna VACCARO, Giovanni GENNARI, Lanfranco CALLEGARO, Antonio GIANNELLI, Salvatore CARUSO
  • Patent number: 8900576
    Abstract: The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase (and relative pharmaceutical formulations) for the preparation of a dressing for topical treatment of various kinds of wounds, burns of varying depth, pressure sores, vascular ulcers and diabetic foot ulcers as well as for the treatment of hypertrophic and keloid scars.
    Type: Grant
    Filed: July 5, 2006
    Date of Patent: December 2, 2014
    Assignee: Fidia Farmaceutici S.p.A
    Inventors: Susanna Vaccaro, Giovanni Gennari, Lanfranco Callegaro, Antonio Giannelli, Salvatore Caruso
  • Patent number: 8865964
    Abstract: There is described a new non-woven fabric produced with the electrospinning technique, and the use thereof as new biomaterial for the biomedical and surgical field.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: October 21, 2014
    Assignee: ANIKA Therapeutics S.r.l.
    Inventors: Davide Bellini, Lanfranco Callegaro, Marie Astier, Fabio Giusti
  • Publication number: 20140221294
    Abstract: This invention relates to oral and intra-articular formulations based on sulphated hyaluronic acid which are effective in the treatment of degenerative osteoarthritis.
    Type: Application
    Filed: April 11, 2014
    Publication date: August 7, 2014
    Inventors: Lanfranco CALLEGARO, Davide RENIER
  • Patent number: 8771672
    Abstract: The present invention regards a biological material comprising: a) a liquid carrier comprising a viscous solution containing at least one natural and/or semisynthetic polysaccharide, and having a Dynamic viscosity measured at 20° C. and at shear rate of D=350 s?1, comprised between 100 and 250 c Poise and/or a Kinematic viscosity comprised between 99 and 248 cSt (measured at the same conditions); b) a culture of mesenchymal stem cells, and/or c) a platelet-rich hemo-derivative. This type of material in form of viscous liquid is particularly suitable for the therapy of osteoarthrosis, ligament damage, in particular tendon and cartilage damage) and may be administered intra-articularly, intradermally or directly applied in situ without altering the properties of the mesenchymal stem cells and/or platelets contained therein.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: July 8, 2014
    Assignee: Fidia Farmaceutici S.p.A.
    Inventors: Lanfranco Callegaro, Anna Maria Zanellato
  • Patent number: 8765714
    Abstract: This invention relates to oral and intra-articular formulations based on sulphated hyaluronic acid which are effective in the treatment of degenerative osteoarthritis.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: July 1, 2014
    Assignee: Fidia Farmaceutici S.p.A.
    Inventors: Lanfranco Callegaro, Davide Renier
  • Patent number: 8263118
    Abstract: The present invention describes a new bioresorbable filler constituted by hyaluronic acid and/or the derivatives thereof structured with/in phospholipid liposomes, which increase the residence time of the starting polymer in situ. Said fillers described herein are substantially intended to increase the soft tissues in aesthetic surgery and dermocosmetics for the correction of mild to medium defects, but because of their special characteristics they can also be used in other fields of application.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: September 11, 2012
    Assignee: Fidia Farmaceutici S.p.A.
    Inventors: Lanfranco Callegaro, Devis Galesso, Anna Taglienti
  • Publication number: 20120165254
    Abstract: This invention relates to oral and intra-articular formulations based on sulphated hyaluronic acid which are effective in the treatment of degenerative osteoarthritis.
    Type: Application
    Filed: March 1, 2012
    Publication date: June 28, 2012
    Applicant: FIDIA FARMACEUTIC S.p.A.
    Inventors: Lanfranco Callegaro, Davide Renier