Patents by Inventor Lanqing HAN

Lanqing HAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETICALLY MODIFIED MOUSE FOR PREPARING ANTIBODY AND METHOD FOR PREPARING GENETICALLY MODIFIED MOUSE
    Publication number: 20260123611
    Abstract: Disclosed in the present disclosure is genetically modified mice in which immunoglobulin loci are modified to insert gene segments of a human immunoglobulin variable region. The mice can be bred normally and produce human-mouse chimeric antibodies including a human variable region and a mouse constant region. The present disclosure also provides a method for preparing the genetically modified mice and use of the mice.
    Type: Application
    Filed: September 3, 2025
    Publication date: May 7, 2026
    Inventors: Lanqing HAN, Cui Su, Xing MOU, Kang WANG, Xiaoliang LI, Liang ZHANG, Xiangyun CHEN, Shun ZHOU, Kugeng HUO
  • GENETICALLY MODIFIED MOUSE FOR PREPARING ANTIBODY AND METHOD FOR PREPARING GENETICALLY MODIFIED MOUSE
    Publication number: 20260114434
    Abstract: Disclosed in the present disclosure is genetically modified mice in which immunoglobulin loci are modified to insert gene segments of a human immunoglobulin variable region. The mice can be bred normally and produce human-mouse chimeric antibodies including a human variable region and a mouse constant region. The present disclosure also provides a method for preparing the genetically modified mice and use of the mice.
    Type: Application
    Filed: September 3, 2025
    Publication date: April 30, 2026
    Inventors: Lanqing HAN, Cui SU, Xing MOU, Kang WANG, Xiaoliang LI, Liang ZHANG, Xiangyun CHEN, Shun ZHOU, Kugeng HUO
  • GENETICALLY MODIFIED MICE FOR PREPARING ANTIBODIES AND PREPARATION METHOD THEREFOR
    Publication number: 20250089690
    Abstract: Disclosed is a genetically modified mouse having an immunoglobulin heavy chain locus engineered to insert a gene segment of a human immunoglobulin heavy chain variable region. The mouse is able to reproduce normally and produce a human-mouse chimeric antibody comprising a human heavy chain variable region and a mouse constant region. Also provided is a method for preparing the genetically modified mouse and use of the mouse.
    Type: Application
    Filed: November 20, 2024
    Publication date: March 20, 2025
    Inventors: Lanqing HAN, Cui SU, Xing MOU, Kang WANG, Xiaoliang LI, Xiaochen ZHAI, Liang ZHANG, Xiangyun CHEN, Shun ZHOU