Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having a proximal end, a distal end, and a pusher lumen extending therebetween; a vaso-occlusive device; and a tubular member mechanically connecting the pusher assembly to the vaso-occlusive device, the tubular member having a proximal end, a distal end, a tube lumen extending therebetween, and a detach zone, wherein the proximal end of the tubular member extends into the pusher assembly lumen at the distal end of the pusher assembly. A heat generating member is disposed in the tube lumen, such that, when activated, the heat generating member generates heat that melts or otherwise thermally degrades the tubular member at the detach zone, thereby detaching the vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having a proximal end, a distal end, and a pusher lumen extending therebetween; a vaso-occlusive device; and a tubular member mechanically connecting the pusher assembly to the vaso-occlusive device, the tubular member having a proximal end, a distal end, a tube lumen extending therebetween, and a detach zone, wherein the proximal end of the tubular member extends into the pusher assembly lumen at the distal end of the pusher assembly. A heat generating member is disposed in the tube lumen, such that, when activated, the heat generating member generates heat that melts or otherwise thermally degrades the tubular member at the detach zone, thereby detaching the vaso-occlusive device from the pusher assembly.

Abstract: A medical device includes an antimicrobial layer. A method of depositing an antimicrobial agent on or in the body of a medical device includes inserting a high temperature resistant tube having multiple holes through its surface into a vascular access device and coating, or delivering an antimicrobial agent to, and interior surface of the device.

Abstract: A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction.

Abstract: A vascular access device may include a body and a layer of the body that communicates with a pathogenic environment to discourage adhesion of a pathogen to the layer and thus repress pathogenic activity. A method of repressing pathogenic activity in a vascular access device includes providing the device with a body, and coating the body with a layer that discourages adhesion of a pathogen to the layer.

Abstract: A vascular access device within an external environment may include a body and a septum at least partially housed within the body. Septum may at least substantially seal a lumen extending through the body. The septum may further include at least a first and a second material. At least one of the materials of the septum may be selected or adapted to resist tearing of the septum.

Abstract: An embolic coil introducer system that may include a catheter having a proximal end, a distal end, a lumen extending between the proximal and distal ends and a longitudinal axis, an embolic coil at least partially disposed in the lumen of the catheter, and a wire for moving the embolic coil at least partially disposed in the lumen of the catheter, the wire having a first diameter along a proximal region of the wire, wherein the catheter includes a locking mechanism that provides a friction fit between the catheter and the wire to hold the wire secure relative to the catheter in a first position when no force is applied to the wire and wherein the friction fit may be overcome by the application of a force to the wire to allow the wire to move relative to the catheter.