Patents by Inventor Laongdao KANGKAEW

Laongdao KANGKAEW has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • [5]Helicene derivatives as molecular reporters for diagnostic applications and methods of synthesis therefor
    Patent number: 11578040
    Abstract: The present invention provides the methods of synthesis of [5]helicene compounds and the use of the said compounds conjugating with biomolecules to work as molecular reporter for diagnostic. The compounds in the present invention have the chemical structure illustrated in the formula (1): wherein G is a connecting group composes of 2 carbon atoms selected from the group consisting of ethane and ethylene; A is a separated or connected group selected from the group consisting of cyano and imide; D1 is selected from the group consisting of oxyalkanoic acid, oxyalkanal and oxyalkanesulfonate; and D2 has structure selected from the group consisting of hydroxyl, oxyalkanoic acid, oxyalkanal, alkyl oxyalkanoate, oxyalkanol and oxyalkanesulfonate. The compounds in the present invention compose of aromatic [5]helicene core comprising long it-conjugating system.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 14, 2023
    Assignee: National Science and Technology Development Agency
    Inventors: Thanasat Sooksimuang, Nitsara Karoonuthaisiri, Ratthaphol Charlermroj, Somboon Sahasithiwat, Waraporn Panchan, Manlika Makornwattana, Sudtida Phuengwas, Laongdao Kangkaew
  • [5]HELICENE DERIVATIVES AS MOLECULAR REPORTERS FOR DIAGNOSTIC APPLICATIONS AND METHODS OF SYNTHESIS THEREFOR
    Publication number: 20200017443
    Abstract: The present invention provides the methods of synthesis of [5]helicene compounds and the use of the said compounds conjugating with biomolecules to work as molecular reporter for diagnostic. The compounds in the present invention have the chemical structure illustrated in the formula (1): wherein G is a connecting group composes of 2 carbon atoms selected from the group consisting of ethane and ethylene; A is a separated or connected group selected from the group consisting of cyano and imide; D1 is selected from the group consisting of oxyalkanoic acid, oxyalkanal and oxyalkanesulfonate; and D2 has structure selected from the group consisting of hydroxyl, oxyalkanoic acid, oxyalkanal, alkyl oxyalkanoate, oxyalkanol and oxyalkanesulfonate. The compounds in the present invention compose of aromatic [5]helicene core comprising long it-conjugating system.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 16, 2020
    Applicant: NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY
    Inventors: Thanasat SOOKSIMUANG, Nitsara KAROONUTHAISIRI, Ratthaphol CHARLERMROJ, Somboon SAHASITHIWAT, Waraporn PANCHAN, Manlika MAKORNWATTANA, Sudtida PHUENGWAS, Laongdao KANGKAEW