Patents by Inventor Larisa Agapova

Larisa Agapova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of deriving differentiated cells from stem cells
    Patent number: 8986995
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: March 24, 2015
    Assignee: International Stem Cell Corporation
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus
  • Methods of Deriving Differentiated Cells from Stem Cells
    Publication number: 20130045534
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Application
    Filed: September 14, 2012
    Publication date: February 21, 2013
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus
  • Methods of deriving definitive endoderm cells from pluripotent parthenogenetic stem cells
    Patent number: 8268621
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: September 18, 2012
    Assignee: International Stem Cell Corporation
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus
  • Methods of Deriving Differentiated Cells from Stem Cells
    Publication number: 20100173414
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Application
    Filed: December 2, 2009
    Publication date: July 8, 2010
    Applicant: INTERNATIONAL STEM CELL CORPORATION
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus