Abstract: A medicine bottle is formed of transparent plastic including a cylindrical container, a peripheral wall, a bottom wall, and an intermediate wall positioned above the bottom wall to define an inaccessible view chamber. A removable cap assembly is mounted on the upper end extent of the peripheral wall and an elongated rod has one end fixedly connected to the removable cap and has an opposite end extending through the intermediate wall and terminating in the view chamber. An indicator disc is threaded on the end of the elongated rod and becomes disconnected from the elongated rod in response to rotation of the rod caused by opening rotation of the cap to provide a subsequent indication of prior removal of the cap from the container.