Patents by Inventor Larry Cummings

Larry Cummings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apatite in-situ restoration
    Patent number: 10583371
    Abstract: The present invention discloses methods of regenerating apatite surfaces, for example after purification of a target analyte.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: March 10, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Larry Cummings
  • Apatite pretreatment
    Patent number: 10427940
    Abstract: Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: October 1, 2019
    Assignee: BIO-RAD LABORATORIES, INC.
    Inventor: Larry Cummings
  • APATITE IN-SITU RESTORATION
    Publication number: 20180345174
    Abstract: The present invention discloses methods of regenerating apatite surfaces, for example after purification of a target analyte.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventor: Larry CUMMINGS
  • Apatite in-situ restoration
    Patent number: 10092857
    Abstract: Methods of regenerating apatite surfaces, for example after purification of a target analyte. The methods include, for example, regeneration that can involve contacting the apatite solid surface with a buffered calcium solution and a zwitterionic buffer, then contacting the apatite solid surface with a phosphate buffered solution, and then contacting the apatite solid surface with a solution comprising a hydroxide.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 9, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Larry Cummings
  • APATITE PRETREATMENT
    Publication number: 20180022608
    Abstract: Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 25, 2018
    Inventor: Larry Cummings
  • Apatite pretreatment
    Patent number: 9802822
    Abstract: Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 31, 2017
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Larry Cummings
  • Apatite In-Situ Restoration
    Publication number: 20150367251
    Abstract: The present invention discloses methods of regenerating apatite surfaces, for example after purification of a target analyte.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventor: Larry Cummings
  • Apatite Pretreatment
    Publication number: 20150368103
    Abstract: Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventor: Larry Cummings
  • DUAL-CHAMBER CHROMATOGRAPHIC CARTRIDGE
    Publication number: 20070114163
    Abstract: A chromatography cartridge with a packed bed is manufactured from an inner and outer chamber, the inner chamber being in an insert that is slidable into the outer chamber with openings in each such that a slurry that is originally placed in the interior of the outer chamber flows into the inner chamber as the parts are being pressed into each other. During the assembly, the particles in the slurry are compressed to fill the smaller volume of the inner chamber and excess liquid is discharged through ports in both chambers. The construction allows for a highly precise and reproducible column filling process with a minimum of steps and operator intervention and thereby low cost and reduced error.
    Type: Application
    Filed: November 16, 2006
    Publication date: May 24, 2007
    Applicant: Bio-Rad Laboratories, Inc.
    Inventor: Larry Cummings
  • Dual-chamber chromatographic cartridge
    Publication number: 20060180536
    Abstract: A chromatography cartridge with a packed bed is manufactured from an inner and outer chamber, the inner chamber being in an insert that is slidable into the outer chamber with openings in each such that a slurry that is originally placed in the interior of the outer chamber flows into the inner chamber as the parts are being pressed into each other. During the assembly, the particles in the slurry are compressed to fill the smaller volume of the inner chamber and excess liquid is discharged through ports in both chambers. The construction allows for a highly precise and reproducible column filling process with a minimum of steps and operator intervention and thereby low cost and reduced error.
    Type: Application
    Filed: February 15, 2005
    Publication date: August 17, 2006
    Applicant: BIO-RAD LABORATORIES, INC., a corporation of the state of Delaware
    Inventor: Larry Cummings