Patents by Inventor Larry E. Kahn

Larry E. Kahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to c-Met for the treatment of cancers
    Publication number: 20040166544
    Abstract: Antibodies specific for c-Met, a protein tyrosine kinase whose ligand is hepatocyte growth factor (HGF), are provided. The antibodies and fragments thereof may block binding of HGF to c-Met. Antagonist antibodies can be employed to block binding of HGF to c-Met or substantially inhibit c-Met activation. The c-Met antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer, pathological liver conditions, and ophthalmic diseases using the c-Met antibodies are also provided.
    Type: Application
    Filed: February 13, 2004
    Publication date: August 26, 2004
    Inventors: Phillip A. Morton, John A. Arbuckle, Michelle L. Evans, William D. Joy, Larry E. Kahn, Jeng-Jong Shieh
  • Thrombopoietin: IL-3 fusion protein
    Patent number: 6254870
    Abstract: The present invention relates to variants of human c-mpl ligands (thrombopoietin) with activity on hematopoietic differentiation and expansion.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: July 3, 2001
    Assignee: G. D. Searle & Co.
    Inventors: Nicholas R. Staten, Jean P. Favara, Larry E. Kahn, Lyle E. Pegg, John P. McKearn, Charles M. Baum
  • Monoclonal antibodies against IgE-associated determinants, hybrid cell lines producing these antibodies, and use therefore
    Patent number: 4940782
    Abstract: The present invention is directed to monoclonal antibodies and hybridomas which produce them, which react with IgE when it is unbound and thereby inhibit IgE binding to mast cells, and react with IgE when it is bound to the B-cell FcE receptor, but do not react with IgE when it is bound to the mast cell FcE receptor.
    Type: Grant
    Filed: June 8, 1987
    Date of Patent: July 10, 1990
    Assignee: G. D. Searle & Co.
    Inventors: Bonita J. Rup, Larry E. Kahn