Patents by Inventor Larry F. O'Neal

Larry F. O'Neal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating Disease with an IL-1R antibody
    Publication number: 20090022733
    Abstract: The invention pertains to methods for treating medical disorders characterized by elevated levels or abnormal expression of IL-1 by administering an IL-1 antagonist, such as soluble type II IL-1 receptor.
    Type: Application
    Filed: March 4, 2008
    Publication date: January 22, 2009
    Inventors: John E. Sims, Larry F. O'Neal
  • Interleukin-1 inhibitors in the treatment of diseases
    Publication number: 20040023869
    Abstract: The invention pertains to methods for treating medical disorders characterized by elevated levels or abnormal expression of IL-1 by administering an IL-1 antagonist, such as soluble type II IL-receptor.
    Type: Application
    Filed: December 20, 2002
    Publication date: February 5, 2004
    Inventors: John E. Sims, Larry F. O'Neal
  • Method for treating cancer
    Publication number: 20020076409
    Abstract: Methods for treating cancer involve administering an interleukin-4 antagonist to a patient diagnosed with cancer. Suitable IL-4 antagonists include, but are not limited to, IL-4 receptors (IL-4R) such as a soluble human IL-4 receptor, antibodies that bind IL-4, antibodies that bind IL-4R, IL-4 muteins that bind to IL-4R but do not induce a biological response, molecules that inhibit IL-4-induced signal transduction, and other compounds that inhibit a biological effect that results from the binding of IL-4 to a cell surface IL-4R. Co-administration of an IL-4 antagonist and an immune stimulatory molecule is also contemplated. Particular antibodies provided herein include human monoclonal antibodies generated by procedures involving immunization of transgenic mice.
    Type: Application
    Filed: July 11, 2001
    Publication date: June 20, 2002
    Inventors: Carl J. March, John D. Pluenneke, Larry F. O'Neal
  • Interleukin-1 inhibitors in the treatment of diseases
    Publication number: 20010053764
    Abstract: The invention pertains to methods for treating medical disorders characterized by elevated levels or abnormal expression of IL-1 by administering an IL-1 antagonist, such as soluble type II IL-1 receptor.
    Type: Application
    Filed: May 11, 2001
    Publication date: December 20, 2001
    Inventors: John E. Sims, Larry F. O'Neal