Abstract: A drilling and grouting device comprises a drill string including a hollow elongate outer rod having a central axis and a hollow elongate inner rod located coaxially within said outer rod, wherein a first outer flow path is defined between said inner and outer rod, and a first central flow path is defined inside said inner rod, a drill bit aligned with said inner rod along said central axis and including a second central flow path, and a crossover part interposed between said inner rod and said drill bit along said central axis, which is configured to connect the first central flow path with a second outer flow path surrounding the drill bit to form a main path and to connect said first outer flow path with said second central flow path to form a secondary path. Also disclosed are systems and methods that include and use the device.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: A drilling and grouting device comprises a drill string including a hollow elongate outer rod having a central axis and a hollow elongate inner rod located coaxially within said outer rod, wherein a first outer flow path is defined between said inner and outer rod, and a first central flow path is defined inside said inner rod, a drill bit aligned with said inner rod along said central axis and including a second central flow path, and a crossover part interposed between said inner rod and said drill bit along said central axis, which is configured to connect the first central flow path with a second outer flow path surrounding the drill bit to form a main path and to connect said first outer flow path with said second central flow path to form a secondary path. Also disclosed are systems and methods that include and use the device.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.

Abstract: A chopper op amp (10) is provided having an input chopping waveform (70). Input chopping waveform E (70) is used to generate waveform C (76) and waveform D (78) for activating switch C (36) and switch D (38), respectively. The high period of waveforms C (76) and D (78) are reduced relative to the chopping waveform (70), thereby corresponding to a reduced duty cycle for chopper op amp (10). The period (88, 90) of chopping waveform (70) may be reduced below two milliseconds.