Patents by Inventor Larry Helms

Larry Helms has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KITS SUITABLE FOR USE IN ELECTROCHEMILUMINESCENCE METHODS AND METHODS OF EFFECTING A SPECIFIC-BINDING NON-WASH ASSAY
    Publication number: 20210109100
    Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
    Type: Application
    Filed: July 23, 2020
    Publication date: April 15, 2021
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Kits suitable for use in electrochemiluminescence methods and methods of effecting a specific-binding non-wash assay
    Patent number: 10753934
    Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 25, 2020
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • KITS SUITABLE FOR USE IN ELECTROCHEMILUMINESCENCE METHODS AND METHODS OF EFFECTING A SPECIFIC-BINDING NON-WASH ASSAY
    Publication number: 20180238882
    Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
    Type: Application
    Filed: February 1, 2018
    Publication date: August 23, 2018
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Kits suitable for use in electrochemiluminescence methods and methods of effecting a specific-binding non-wash assay
    Patent number: 9891221
    Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: February 13, 2018
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME
    Publication number: 20140336070
    Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
    Type: Application
    Filed: June 30, 2014
    Publication date: November 13, 2014
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Stromgren, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Assay buffer, compositions containing the same, and methods of using the same
    Patent number: 8785201
    Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: July 22, 2014
    Assignee: Meso Scale Technologies, LLC
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME
    Publication number: 20090170121
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Application
    Filed: February 10, 2009
    Publication date: July 2, 2009
    Applicant: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Assay buffer, compositions containing the same, and methods of using the same
    Patent number: 7491540
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: February 17, 2009
    Assignee: Meso Scale Technologies, LLC
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Assay buffer, compositions containing the same, and methods of using the same
    Patent number: 7288410
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: October 30, 2007
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Multi-array, multi-specific electrochemiluminescence testing
    Publication number: 20060068499
    Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.
    Type: Application
    Filed: October 31, 2005
    Publication date: March 30, 2006
    Inventors: Jacob Wohlstadter, James Wilbur, George Sigal, Mark Martin, Liang-Hong Guo, Alan Fischer, Jon Leland, Mark Billadeau, Larry Helms, Ramin Darvari
  • Assay buffer, compositions containing the same, and methods of using the same
    Patent number: 6919173
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: July 19, 2005
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Assay buffer, compositions containing the same, and methods of using the same
    Publication number: 20050136497
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Application
    Filed: February 9, 2005
    Publication date: June 23, 2005
    Inventors: Michael Tsionsky, Eli Glezer, Selen Altunata, George Sigal, Jonathan Leland, Mark Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Assay buffer, compositions containing the same, and methods of using the same
    Publication number: 20050136048
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Application
    Filed: February 9, 2005
    Publication date: June 23, 2005
    Inventors: Michael Tsionsky, Eli Glezer, Selen Altunata, George Sigal, Jonathan Leland, Mark Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Functionalized nanotubes
    Publication number: 20040202603
    Abstract: Graphitic nanotubes, which includes tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution or by adsorption of functional moieties. More specifically the invention relates to graphitic nanotubes which are uniformly or non-uniformly substituted with chemical moieties or upon which certain cyclic compounds are adsorbed and to complex structures comprised of such functionalized nanotubes linked to one another. The invention also relates to methods for introducing functional groups onto the surface of such nanotubes. The invention further relates to uses for functionalized nanotubes.
    Type: Application
    Filed: April 30, 2004
    Publication date: October 14, 2004
    Applicant: Hyperion Catalysis International, Inc.
    Inventors: Alan Fischer, Robert Hoch, David Moy, Ming Lu, Mark Martin, Chun Ming Niu, Naoya Ogata, Howard Tennent, Liwen Dong, Ji Sun, Larry Helms, Fabian Jameison, Pam Liang, David Simpson
  • Assay buffer, compositions containing the same, and methods of using the same
    Publication number: 20030175803
    Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.
    Type: Application
    Filed: September 10, 2002
    Publication date: September 18, 2003
    Inventors: Michael Tsionsky, Eli N. Glezer, Selen Altunata, George Sigal, Jonathan K. Leland, Mark A. Billadeau, Svetlana Leytner, Mark Martin, Larry Helms
  • Drywall cutting device
    Patent number: 5083375
    Abstract: A drywall cutting device adapted for use with a piece of conventional drywall. The device includes a slidetrack which can be mounted on an edge of a piece of drywall and guide rails which extend substantially perpendicularly from the slidetrack, such that when the slidetrack is placed on an edge of a piece of drywall, the guide rails extend out over the piece of drywall. Slidably mounted on the guide rails is a cutting means holding device, which holds a cutting means such as a knife blade or razor.The drywall cutting device cuts drywall as follows; the slidetrack is placed on an edge of a piece of drywall, the device is slid to the desired cut point, the cutting means is aligned in the desired cut direction, and the cutting means holding device is slide into position on the guide rails. The desired cut is then made by sliding the drywall cutting device along the edge. Use of the present invention will thus result in savings of time and cost to the user.
    Type: Grant
    Filed: June 13, 1991
    Date of Patent: January 28, 1992
    Inventor: Larry Helm, Sr.