Patents by Inventor Larry Margerum

Larry Margerum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biodegradable blood-pool contrast agents
    Patent number: 6010681
    Abstract: The invention provides a blood pool contrast agent having an overall molecular weight of at least 10KD comprising a macrostructure which has bound thereto a plurality of opsonization inhibiting moieties and carries chelated ionic paramagnetic or heavy metal moieties, the chelant groups for said chelated moieties being macrocyclic where said macrostructure is liposomal.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: January 4, 2000
    Assignee: Nycomed Salutar, Inc.
    Inventors: Larry Margerum, Brian Campion, Jere Douglas Fellmann, Martha Garrity, John Varadarajan
  • Dendrimeric compounds
    Patent number: 5834020
    Abstract: The invention provides a dendrimeric compound comprising a dendrimeric bioactive moiety with linked thereto a plurality of diagnostically or therapeutically active moieties characterized in that the molecular skeleton of said compound contains at least one biodegradable cleavage site such that on cleavage thereof said active moieties are released in renally excretable form.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 10, 1998
    Assignee: Nycomed Salutar, Inc.
    Inventors: Larry Margerum, Brian Campion, Jere Douglas Fellmann, Martha Garrity