Abstract: Provided are compounds and compositions for targeting macrophages and other mannose-binding c-type lectin receptor high expressing cells and methods of treatment and diagnosis using such compounds and compositions.

Abstract: Provided are compounds and compositions for targeting macrophages and other CD206 high expressing cells.

Abstract: Compositions and methods for preventing and treating infection with multi-drug resistant bacteria with AR-13 alone or in combination with antibiotics are provided.

Abstract: Provided are compounds and compositions for targeting macrophages and other CD206 high expressing cells.

Abstract: Provided are compounds and compositions for targeting macrophages and other mannose-binding c-type lectin receptor high expressing cells and methods of treatment and diagnosis using such compounds and compositions.

Abstract: Compositions and methods for preventing and treating infection with multi-drug resistant bacteria with AR-13 alone or in combination with antibiotics are provided.

Abstract: Methods of treating bacterial infection by in a subject by administering a pharmaceutical composition including a celecoxib derivative are described. The compounds are particularly useful for treating infection by bacteria capable of growing inside macrophages, such as Myocobacteria tuberculosis.

Abstract: Compositions and methods for inhibiting viral protein production, viral infection, and viral replication in a host or host cells infected with a virus (e.g., influenza, Junin, Chikungunya, Dengue, HIV, RHDV) by administering AR-12 and AR-12 analogs are provided.

Abstract: Methods of treating bacterial infection by in a subject by administering a pharmaceutical composition including a celecoxib derivative are described. The compounds are particularly useful for treating infection by bacteria capable of growing inside macrophages, such as Myocobacteria tuberculosis.

Abstract: Tamper-proof cap systems and methods for use with an access valve, such as a refrigeration access valve, are provided. A tamper-proof cap assembly for use with an access valve can include a cylindrical outer cap and a cylindrical inner cap, wherein the inner cap captively resides within and rotates freely within the outer cap. The inner cap of a tamper-proof cap assembly can threadingly receive the threaded end of an access valve. A tamper-proof cap system can include a tamper-proof cap assembly and a tool for manipulating the inner cap such that a user with the tool can manipulate the tamper-proof cap and screw it onto or off of an access valve. Without the tool the tamper-proof cap cannot be removed from the access valve.

Abstract: Systems and methods for monitoring tires of a vehicle are provided. The systems can include a sensing device adapted to engage a tire of a vehicle and sense properties of a tire such as pressure and/or temperature. The sensing devices can be adapted to transmit sensed data to a system receiver adapted to provide the data to a user. The systems and methods can provide a user the desired information pertaining to one or more tires of a vehicle that are to be monitored, and the respective locations of the tires. The systems and methods can be adapted to monitor tires on any vehicle with inflatable tires, including off-the-road (OTR) vehicles.

Abstract: Tire pressure monitoring apparatuses, systems and method for adapting a tire pressure monitoring apparatus to be used with a plurality of valve stem configurations. Tire pressure monitoring transducers and sensors designed for use with a single valve stem design can be modified to universally accept a plurality of valve stems when coupled with the presently disclosed adapter. Use of an adapter of the presently disclosed subject matter can adapt a tire pressure monitoring apparatus such that it is suitable for use with a wide range of existing valve stems, including valve stems not originally designed to be used with the tire pressure monitoring apparatus. The adapter is suitable for use with tire pressure monitoring transducers and sensors.

Abstract: Tamper-proof cap systems and methods for use with an access valve, such as a Schrader valve, are provided. A tamper-proof cap assembly for use with an access valve can include a cylindrical outer cap and a cylindrical inner cap, wherein the inner cap captively resides within and rotates freely within the outer cap. The inner cap of a tamper-proof cap assembly can threadingly receive the threaded end of an access valve. A tamper-proof cap system can include a tamper-proof cap assembly and a tool for manipulating the inner cap such that a user with the tool can manipulate the tamper-proof cap and screw it onto or off of an access valve. Without the tool the tamper-proof cap cannot be removed from the access valve.

Abstract: Systems and methods for monitoring tires of a vehicle are provided. The systems can include a sensing device adapted to engage a tire of a vehicle and sense properties of a tire such as pressure and/or temperature. The sensing devices can be adapted to transmit sensed data to a system receiver adapted to provide the data to a user. The systems and methods can provide a user the desired information pertaining to one or more tires of a vehicle that are to be monitored, and the respective locations of the tires. The systems and methods can be adapted to monitor tires on any vehicle with inflatable tires, including off-the-road (OTR) vehicles.

Abstract: Tire pressure monitoring apparatuses, systems and method for adapting a tire pressure monitoring apparatus to be used with a plurality of valve stem configurations. Tire pressure monitoring transducers and sensors designed for use with a single valve stem design can be modified to universally accept a plurality of valve stems when coupled with the presently disclosed adapter. Use of an adapter of the presently disclosed subject matter can adapt a tire pressure monitoring apparatus such that it is suitable for use with a wide range of existing valve stems, including valve stems not originally designed to be used with the tire pressure monitoring apparatus. The adapter is suitable for use with tire pressure monitoring transducers and sensors.