Patents by Inventor Larry Tait

Larry Tait has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Three-dimensional in vitro model of human preneoplastic breast disease
    Patent number: 6828111
    Abstract: A three-dimensional in vitro culture system comprising breast epithelial cells, endothelial cells and breast fibroblasts supports growth and functional differentiation of preneoplastic breast epithelial cells and endothelial cells and recapitulates estrogen induced in vivo effects on angiogenesis and proliferative potential of breast epithelial tissue. This model permits the generation of functional vascular networks and local proliferative ductal alveolar outgrowths with invasive potential. Both these processes are augmented by estrogen. This culture model is used to evaluate agents for their effects, whether stimulatory or inhibitory, on preneoplastic breast disease and its progression to cancer.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: December 7, 2004
    Assignee: Wayne State University
    Inventors: Malathy P. V. Shekhar, Larry Tait
  • Three-dimensional in vitro model of human preneoplastic breast disease
    Publication number: 20010055804
    Abstract: A three-dimensional in vitro culture system comprising breast epithelial cells, endothelial cells and breast fibroblasts supports growth and functional differentiation of preneoplastic breast epithelial cells and endothelial cells and recapitulates estrogen induced in vivo effects on angiogenesis and proliferative potential of breast epithelial tissue. This model permits the generation of functional vascular networks and local proliferative ductal alveolar outgrowths with invasive potential. Both these processes are augmented by estrogen. This culture model is used to evaluate agents for their effects, whether stimulatory or inhibitory, on preneoplastic breast disease and its progression to cancer.
    Type: Application
    Filed: January 16, 2001
    Publication date: December 27, 2001
    Inventors: Malathy P.V. Shekhar, Larry Tait