Patents by Inventor Larry Wayne Mann

Larry Wayne Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tie-2 modulators and methods of use
    Patent number: 8013156
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Tie-2. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: September 6, 2011
    Assignee: Exelixis, Inc.
    Inventors: Lynne Canne Bannen, S. David Brown, Wei Cheng, Vasu Jammalamadaka, John M. Nuss, Morrison B. Mac, Jason Jevious Parks, Matthew A. Williams, Wei Xu, Atwood Kim Cheung, Lisa Esther Dalrymple, Sergey Epshteyn, Mohamed Abdulkader Ibrahim, James William Leahy, Gary Lee Lewis, Robin Tammie Noguchi, Larry Wayne Mann, Brian Hugh Ridgway, Joan C. Sangalang, Kevin Luke Schnepp, Xian Shi, Richard George Khoury
  • Protein kinase modulators and methods of use
    Patent number: 7704995
    Abstract: This invention relates to compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion, and to pharmaceutical compositions containing such compounds. Even more specifically, the invention relates to compounds that inhibit, regulate and/or modulate kinases, particularly Checkpoint Kinases, even more particularly Checkpoint Kinase 1, or Chk1. Methods of therapeutically or prophylactically using the compounds and compositions to treat kinase-dependent diseases and conditions are also an aspect of the invention, and include methods of treating cancer, as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, by administering effective amounts of such compounds.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: April 27, 2010
    Assignee: Exelixis, Inc.
    Inventors: Chris A. Buhr, Tae-Gon Baik, Sunghoon Ma, Zerom Tesfai, Longcheng Wang, Erick Wang Co, Sergey Epshteyn, Abigail R Kennedy, Baili Chen, Larisa Dubenko, Neel Kumar Anand, Tsze H. Tsang, John M. Nuss, Csaba J Peto, Kenneth D. Rice, Mohamed Abdulkader Ibrahim, Kevin Luke Schnepp, Xian Shi, James William Leahy, Jeff Chen, Lisa Esther Dalrymple, Timothy Patrick Forsyth, Tai Phat Huynh, Grace Mann, Larry Wayne Mann, Craig Stacy Takeuchi, Peter Lamb, David J. Matthews, Nicole Miller
  • Apparatus and method for boat engine exhaust injection system
    Patent number: 7387555
    Abstract: An apparatus and method for injecting a boat engine's exhaust gasses into the boat propeller's propwash, aft of the propeller. The apparatus comprises piping which injects the boat engine's exhaust gasses into the propwash of the boat, aft of the propeller. This results in the movement of the exhaust gasses away from the boat thus protecting the health of the boat occupants, reduced levels of air pollutants, and a reduction in noise pollution. The injection piping includes several features that protect the boat in the event that the injection piping should strike a solid object in the water.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: June 17, 2008
    Inventor: Larry Wayne Mann
  • Apparatus and method for a dual hull boat with control gate
    Patent number: 7216601
    Abstract: The current invention is an apparatus and method for an inner and outer dual hull boat capable of transforming between different levels of planing ability. The design is a gateway in the outer hull which allows water to pass through the void between the inner and outer hull. By controlling the position of a gate, the flow of water through the gateway in the forward moving boat can be controlled, which allows for the control of the planing or displacement capacity of the boat.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: May 15, 2007
    Inventor: Larry Wayne Mann
  • Apparatus and method for a gliding board for fluid riding sports
    Patent number: 6935909
    Abstract: A curved lower surface of a gliding board, such as a wakeboard or a surfboard, is provided with an anticlastic shape to resemble the shape of a saddle. The lower surface of the board is concave in a transverse cross section and convex in a longitudinal cross section along the entire length of the board.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: August 30, 2005
    Inventor: Larry Wayne Mann
  • Apparatus and method for a gliding board for fluid riding sports
    Publication number: 20040176000
    Abstract: An apparatus and method for utilization as a gliding board, such as a wake surfboard. The apparatus is the lower surface 26 of said gliding board and is a curved planar surface in a saddle or anticlastic shape. The resulting curved planar lower surface 26 of the gliding board exhibits excellent gliding properties over a fluid medium.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 9, 2004
    Inventor: Larry Wayne Mann