Patents by Inventor Lars A. Solli

Lars A. Solli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device for carrying out cell lysis and nucleic acid extraction
    Patent number: 8404440
    Abstract: The present invention provides an integrated lab-on-a-chip device for carrying out a nucleic acid extraction process on a fluid sample containing cells and/or particles, the device comprising: (a) a sample inlet (1) for loading of a fluid sample, (b) a lysis unit (4) for lysis of cells and/or particles present in the fluid sample, (c) a reservoir of lysis fluid (7) for the lysis unit, (d) a nucleic acid extraction unit (5) downstream of the lysis unit, and (e) reservoirs of first washing buffer and eluant fluid (8, 9, 10) for the nucleic acid extraction unit, wherein the device further comprises (f) a mixing unit (6) downstream of the nucleic acid extraction unit, and (g) a source of mixing fluid (11) for the mixing unit. The reservoirs of lysis fluid, first washing buffer and eluant fluid may be provided parallel to one anther so that they may be actuated by a single pump.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: March 26, 2013
    Assignee: Norchip A/S
    Inventors: Lars A. Solli, Anja Gulliksen, Frank Karlsen, Tobias Baier, Rainer Gransee, Thomas Hansen-Hagge, Klaus Stefan Drese, Liv Furuberg
  • DEVICE FOR CARRYING OUT CELL LYSIS AND NUCLEIC ACID EXTRACTION
    Publication number: 20100297754
    Abstract: The present invention provides an integrated lab-on-a-chip device for carrying out a nucleic acid extraction process on a fluid sample containing cells and/or particles, the device comprising: (a) a sample inlet (1) for loading of a fluid sample, (b) a lysis unit (4) for lysis of cells and/or particles present in the fluid sample, (c) a reservoir of lysis fluid (7) for the lysis unit, (d) a nucleic acid extraction unit (5) downstream of the lysis unit, and (e) reservoirs of first washing buffer and eluant fluid (8, 9, 10) for the nucleic acid extraction unit, wherein the device further comprises (f) a mixing unit (6) downstream of the nucleic acid extraction unit, and (g) a source of mixing fluid (11) for the mixing unit. The reservoirs of lysis fluid, first washing buffer and eluant fluid may be provided parallel to one anther so that they may be actuated by a single pump.
    Type: Application
    Filed: June 9, 2008
    Publication date: November 25, 2010
    Applicant: Norchip A/S
    Inventors: Lars A. Solli, Anja Gulliksen, Frank Karlsen, Tobias Baier, Rainer Gransee, Thomas Hansen-Hagge, Klaus Stefan Drese, Liv Furuberg