Patents by Inventor Lars Abrahamsen

Lars Abrahamsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Promoter sequences
    Patent number: 7045294
    Abstract: The present invention relates an isolated human Site-1 Protease promoter region. The invention also relates to screening methods for agents decreasing the expression of Site-1 protease and thereby being potentially useful for the treatment of medical conditions related to obesity and/or diabetes.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: May 16, 2006
    Assignee: Biovitrum AB
    Inventors: Lars Abrahamsén, Jonas Ekblom, Margareta Forsgren, Jan Hörling, Per Johansson
  • Expression system for producing apolipoprotein AI-M
    Patent number: 5721114
    Abstract: The invention relates to an expression system giving high extracellular production of apolipoprotein AI-M (Milano) using E. coli and comprises a plasmid carrying an origin of replication, an inducible promoter sequence, a DNA sequence coding for a signal peptide, a DNA sequence coding for apolipoprotein AI-M, and a transcription terminator. The invention also relates to a method of producing apolipoprotein AI-M using the expression system.
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: February 24, 1998
    Assignee: Pharmacia & Upjohn Aktiebolag
    Inventors: Lars Abrahamsen, Erik Holmgren, Christina Kalderen, Mats Lake, .ANG.sa Mikaelsson, Torsten Sejlitz