Abstract: A method for manufacturing the powder: component for a cement for medical use includes a liquid component containing a polymerizable substance and a powder component containing a plastic substance and an X-ray contrast medium. The liquid component and the powder component are mixed for providing a setting mass which is set to form the cement. In order to prevent the formed cement from releasing particles wearing on articulating or bearing surfaces adjacent ;the point of cementation, a water soluble, non-ionic X-ray contrast medium is mixed with the plastic substance, and for minimizing the risk of damaging the powder component during the sterilization, sterilizing by radiation of the powder component containing the X-ray contrast medium is carried through a negative pressure or in an inert gas atmosphere.

Abstract: The present invention relates to a mixing device for the manufacture of bone cement by mixing components intended therefor, said mixing device including a mixing member (1) with a mixing space (2) for mixing of said components (11, 12). A vacuum-generating device (17) is provided to generate a vacuum in the mixing space (2) for mixing said components (11, 12) under vacuum. A mixing means (10) is provided to mix the components (11, 12) with each other in the mixing space (2). A sealed container (20) with one of the components (12) is provided in an outer container (22). The sealed container (20) can be opened when it is provided in the outer container (22) to permit flow of one of the components (12) to the other component (11) in the mixing space (2) for mixing of said components (11, 12).