Patents by Inventor Lars Barfacker

Lars Barfacker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-arylmethyl substituted pyrazolo[3,4-d]pyrimidines
    Patent number: 8809348
    Abstract: The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: August 19, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Barfacker, Christine Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • 3-cyano 5-thiazaheteroaryl-dihydropyridine and the use thereof for the treatment of cardiovascular diseases
    Patent number: 8404723
    Abstract: The present application relates to novel aryl-substituted 3-cyano-5-thiazolyl- and 3-cyano-5-thiadiazolyl-1,4-dihydropyridines, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
    Type: Grant
    Filed: September 8, 2007
    Date of Patent: March 26, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Lars Barfacker, Peter Kolkhof, Karl-Heinz Schlemmer, Rolf Grosser, Adam Nitsche
  • 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF
    Publication number: 20100298221
    Abstract: The present invention relates to novel 2-phenoxy-6-phenyl- and 2-phenoxy-6-pyridylnicotinic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prophylaxis of cardiovascular disorders, especially of dyslipidemias, arteriosclerosis and heart failure.
    Type: Application
    Filed: August 30, 2007
    Publication date: November 25, 2010
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Heinrich Meier, Peter kolkhof, Axel Kretschmer, Arounarith Tuch, Lars Barfacker, Yolanda Cancho Grande
  • 3-Cyano-5-thiazaheteroaryl-dihydropyridine and the use thereof for the treatment of cardiovascular diseases
    Publication number: 20100240620
    Abstract: The present application relates to novel aryl-substituted 3-cyano-5-thiazolyl- and 3-cyano-5-thiadiazolyl-1,4-dihydropyridines, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
    Type: Application
    Filed: September 8, 2007
    Publication date: September 23, 2010
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Lars Barfacker, Peter Kolkhof, Karl-Heinz Schlemmer, Rolf Grosser, Adam Nitsche
  • Novel Pyrimidine Derivatives and their Use
    Publication number: 20080261990
    Abstract: The present invention relates to novel pyrimidine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular diseases, in particular dyslipidemias, arteriosclerosis, coronary heart disease, thrombosis and metabolic syndrome.
    Type: Application
    Filed: September 10, 2005
    Publication date: October 23, 2008
    Applicant: Bayer healthCare AG
    Inventors: Elke Dittrich-Wengenroth, Lars Barfacker, Axel Kretschmer, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Hilmar Bischoff, Christian Pilger, Ulrich Rosentreter, Stephan Bartel, Klemens Lustig, Armin Kern, Dieter Lang, Marcus Bauser
  • Phenylthioacetic Acid Derivatives and Use Thereof
    Publication number: 20080255202
    Abstract: The present application relates to novel phenylthioacetic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, in particular dyslipidaemias and arteriosclerosis.
    Type: Application
    Filed: March 26, 2005
    Publication date: October 16, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Nils Griebenow, Axel Kretschmer, Joachim Kruger, Elisabeth Woltering, Lars Barfacker, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Stephen Bartel, Christian Pilger, Ulrich Rosentreter, Klemens Lustig, Armin Kern, Dieter Lang
  • Cyanopyrimidinones
    Publication number: 20080255118
    Abstract: The invention relates to novel cyanopyrimidinones, process for their preparation, and the use thereof for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: December 31, 2004
    Publication date: October 16, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Martin Hendrix, Lars Barfacker, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen
  • Pyrimidine Carboxylic Acid Derivatives and Use Thereof
    Publication number: 20080194598
    Abstract: The present application relates to pyrimidinecarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, in particular dyslipidaemias and arteriosclerosis.
    Type: Application
    Filed: March 7, 2006
    Publication date: August 14, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Elisabeth Woltering, Arounarith Tuch, Elke Dittrich-Wengenroth, Axel Kretschmer, Lars Barfacker, Marcus Bauser, Peter Ellinghaus, Klemens Lustig, Elisabeth Pook, Olaf Weber
  • Phenyl Acetamides
    Publication number: 20080176898
    Abstract: The present invention relates to phenylacetamides, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, especially of cardiovascular disorders.
    Type: Application
    Filed: April 14, 2005
    Publication date: July 24, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Michael Harter, Frank Wunder, Lars Barfacker, Gunter Karig, Walter Hubsch, Hanna Tinel, Eva-Maria Becker
  • 6-Arylmethyl-substituted pyrazolopyrimidines
    Publication number: 20070161662
    Abstract: The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: April 27, 2004
    Publication date: July 12, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Martin Hendrix, Lars Barfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • 6-Arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors
    Publication number: 20070105881
    Abstract: The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.
    Type: Application
    Filed: June 16, 2004
    Publication date: May 10, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Martin Hendrix, Lars Barfacker, Bettina Beyreuther, Ulrich Ebert, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Yan-Hong Liu, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • 6-Cyclylmethyl- and 6-alkylmethyl-substituted pyrazolepyrimidines
    Publication number: 20070105876
    Abstract: The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: April 28, 2004
    Publication date: May 10, 2007
    Inventors: Martin Hendrix, Lars Barfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Pyrimidinone derivaties as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
    Publication number: 20060160801
    Abstract: The invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases.
    Type: Application
    Filed: August 28, 2003
    Publication date: July 20, 2006
    Inventors: Heike Gielen-Haertwig, Volkhart Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allertheiligen, Leila Telan, Lars Barfacker, Jorg Keldenich, Mary Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Isophtalic acid derivatives
    Publication number: 20060154912
    Abstract: The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders.
    Type: Application
    Filed: November 28, 2003
    Publication date: July 13, 2006
    Inventors: Michael Harter, Jens Erguden, Frank Wunder, Hanna Tinel, Johannes Kobberling, Eva-Maria Becker, Klaus Munter, Karl-Heinz Schlemmer, Raimund Kast, Peter Kolkhof, Gunter Karig, Lars Barfacker, Walter Hubsch, Joachim Schuhmacher, Susanne Zuleger, Arnel Concepcion, Haruka Shimizu
  • Heterocyclic derivatives
    Publication number: 20060111377
    Abstract: The invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Application
    Filed: August 28, 2003
    Publication date: May 25, 2006
    Applicant: Bayer Healthcare A G
    Inventors: Heike Gielen-Haertwig, Volkhart Li, Ulrich Rosentreter, Karl-Heinz Schlemer, Swen Sllerheiligen, Leila Telan, Lars Barfacker, Jorg Keldenich, Mary Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Dihydropyridinone derivatives
    Publication number: 20060100207
    Abstract: The invention relates to novel dihydropyridinone derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Application
    Filed: August 18, 2003
    Publication date: May 11, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Barfacker, Jorg Keldenich, Mary Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer