Patents by Inventor Lars Bjorklund

Lars Bjorklund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dopaminergic neurons differentiated from embryonic cells for treating neurodegenerative diseases
    Patent number: 8153422
    Abstract: Disclosed herein are methods for generating dopaminergic neurons in vitro by inhibiting a pathway component of a TGF-? signaling pathway and overexpressing one or more cell fate-inducing polypeptides in pluripotent cells, causing differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: April 10, 2012
    Assignee: The McLean Hospital Corporation
    Inventors: Ole Isacson, Lars Bjorklund
  • DOPOMINERGIC NEURONS DIFFERENTIATED FROM EMBRYONIC CELLS FOR TREATING NEURODEGENERATIVE DISEASES
    Publication number: 20080274548
    Abstract: Disclosed herein are methods for generating dopaminergic neurons in vitro by inhibiting a pathway component of a TGF-? signaling pathway and overexpressing one or more cell fate-inducing polypeptides in pluripotent cells, causing differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.
    Type: Application
    Filed: April 22, 2008
    Publication date: November 6, 2008
    Inventors: Ole Isacson, Lars Bjorklund
  • Dopaminergic neurons differentiated from embryonic cells for treating neurodegenerative diseases
    Publication number: 20040214324
    Abstract: Disclosed herein are methods for generating dopaminergic neurons in vitro by inhibiting a pathway component of a TGF-&bgr; signaling pathway and overexpressing one or more cell fate-inducing polypeptides in pluripotent cells, causing differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.
    Type: Application
    Filed: December 9, 2003
    Publication date: October 28, 2004
    Inventors: Ole Isacson, Lars Bjorklund
  • Load gate and method of operating a forwarder using the same
    Patent number: 6558105
    Abstract: A preferred embodiment of the present invention provides an apparatus and method of a load gate. A forwarder includes a load gate, a frame, a power source, an operator station, at least one propulsion device, at least one load retaining member, an implement, all of these arranged into a tractor and a trailer. The load gate includes at least one window and at least one transparent pane covering the windows.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: May 6, 2003
    Assignee: Caterpillar Inc
    Inventors: Lars Bjorklund, Timothy G. Sidles
  • Load gate and method of operating a forwarder using the same
    Publication number: 20020071753
    Abstract: A preferred embodiment of the present invention provides an apparatus and method of a load gate. A forwarder includes a load gate, a frame, a power source, an operator station, at least one propulsion device, at least one load retaining member, an implement, all of these arranged into a tractor and a trailer. The load gate includes at least one window and at least one transparent pane covering the windows.
    Type: Application
    Filed: November 29, 2000
    Publication date: June 13, 2002
    Inventors: Lars Bjorklund, Timothy G. Sidles
  • Load gate
    Patent number: D460086
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: July 9, 2002
    Assignee: Caterpillar Inc.
    Inventors: Lars Bjorklund, Timothy G. Sidles