Abstract: A pinch valve having a clamping member (300) mounted between two side walls (110) of a valve housing, the side walls extending parallel to a hose guide axis and to a plunger guide axis. Each of the side walls has a step (112) extending parallel to the hose guide axis and recessing with respect to the advancing direction of the plunger. The clamping jaws (320) of the pinch valve, upon displacement of the clamping member (300), move over the steps (112) with their outer sides, which face away from the hose guide, bearing against the side walls (110).

Abstract: Various embodiments relate to an aeration device for a bioprocessing installation, in particular a bioreactor, comprising a housing, wherein the housing comprises one or more aeration channels in its interior, wherein the housing further comprises one or more gas inlet ports, via each of which a gas can be introduced into at least one aeration channel of the housing, and wherein the housing further comprises a plurality of gas outlet ports, via each of which the gas can be discharged from the respective aeration channel to the outside of the aeration device. It is proposed that the aeration device is configurable with respect to a predetermined discharge of gas via the gas outlet ports.

Abstract: The invention relates to a modular processing system for biopharmaceutical and/or chemical processes, comprising: at least one processing unit; at least one adapter plate, which can be directly or indirectly fluidically connected to the processing unit, wherein the adapter plate has at least one adapter channel, through which at least one fluid flow can flow to the processing unit, wherein the adapter plate also has at least one deflection element and/or a pump and/or at least one valve; and an external control device. The adapter plate is designed in such a way that the fluid flow to the processing unit can be at least partially deflected with the at least one deflection element in the adapter channel and/or the fluid flow, preferably its pressure, is controllable with the at least one valve and/or the pump in the adapter channel.

Abstract: The invention relates to a pinch valve comprising a valve element (4) with precisely one flow channel (20) that is surrounded by a circumferential wall (21) and has an inlet opening (24), which is designed for connecting a connection member (2) or which adjoins a connection element (2a), at a first end and an outlet opening (25), which is designed for connecting a connection member (2) or adjoins a connection element (2a), at a second end. The valve element (4) additionally has a pair of force transmitting elements (19, 19?) or a force transmitting element (19) and a fixing element (26) which are connected to the circumferential wall (21) in a central closing region (18) that is arranged between the inlet opening and the outlet opening. The force transmitting elements (19, 19?) or the force transmitting element (19) and the fixing element (26) are arranged at least substantially perpendicularly to the flow direction of the flow channel (20).

Abstract: The present invention relates to a mixing device having a stirring element that comprises: a container for receiving fluids and/or solids; and at least one rotatable stirring element for mixing the fluids and/or solids; wherein the stirring element comprises a first bearing element and a second bearing element which are arranged at or near opposite ends of the stirring element; wherein the first bearing element is mounted on a first face of the container and the second bearing element is mounted on an opposite second face of the container; wherein the first bearing element comprises at least one non-permanently magnetized element such that it can be moved in rotation by externally induced reluctance forces, and wherein the second bearing element is mounted in a contactless manner by externally induced magnetic forces. The invention also relates to a mixing device system.

Abstract: The invention relates to a service unit that can be carried on the body of a user by means of a carrying system, having at least one power source for supplying power to electrically operated tools connectable to the power source, the power source being formed from at least one rechargeable battery. The invention also relates to a method for monitoring and documenting maintenance work. The invention is distinguished in that the carrying system has an integrated computation and documentation unit for monitoring and documenting maintenance work, wherein the computation and documentation unit is powered from the power source, wherein the computation and documentation unit is connected to at least one motion sensor and/or locating sensor and wherein the motion sensor is arranged on the tool or the hand of the user.

Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.

Abstract: A method for configuring a clean room (2) for the manufacture of pharmaceutical products and the manufacture of pharmaceutical products includes the steps: selecting a pharmaceutical product for the manufacture in the clean room (2); determining one or a plurality of specific devices (16) and/or one or a plurality of specific materials (18) for the manufacture of the selected pharmaceutical product; and assigning locations for the particular, respectively specific devices (16) and/or specific materials (18) in the clean room (2) and, that is, by using a navigation system (4). The navigation system (4) issues at least one notification (6, 8, 10, 12, 14) associated with a location in the clean room (2) indicating where the specific device (16) and/or the specific material (18) for the manufacture of the selected pharmaceutical product is/are to be placed.

Abstract: The invention relates to a pinch valve comprising a valve element (4) with precisely one flow channel (20) that is surrounded by a circumferential wall (21) and has an inlet opening (24), which is designed for connecting a connection member (2) or which adjoins a connection element (2a), at a first end and an outlet opening (25), which is designed for connecting a connection member (2) or adjoins a connection element (2a), at a second end. The valve element (4) additionally has a pair of force transmitting elements (19, 19?) or a force transmitting element (19) and a fixing element (26) which are connected to the circumferential wall (21) in a central closing region (18) that is arranged between the inlet opening and the outlet opening. The force transmitting elements (19, 19?) or the force transmitting element (19) and the fixing element (26) are arranged at least substantially perpendicularly to the flow direction of the flow channel (20).

Abstract: A mixing vessel for accommodating components to be mixed has a container with at least one mounting depression in a side wall of the container. The mounting depression is adapted so that a mixing impeller housing of a mixing impeller is at least partly insertable, in which at least one magnet is housed for being magnetically connectable to a drive device to be driven. A locking assembly is attachable to the mounting depression from outside for locking the mixing impeller in a storage position, in which the mixing impeller is not rotatable. The locking assembly has a magnetically active element that is adapted to interact with the magnet of the mixing impeller.

Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).

Abstract: A presterilizable filtration system is provided and is to be disposed of after a single use. The system has a recirculation tank and a filtration module that are connected to each other in a circuit via a hose system that can be regulated by at least one valve. The valve has a disposable separate valve part that can be integrated in the hose system and a reusable actuator.

Abstract: A method is provided for monitoring a flow behavior of mixed components without requiring additional instrumentation or sampling. The method is carried out by determining ratios of the power required to rotate a mixing impeller at different rotational speeds and then comparing the ratios. Characteristics about the mixed components are determined based on differences between the ratios.

Abstract: A mixing method, a controller and a mixing device for mixing components in a mixing vessel are provided. The mixing method includes providing a mixing impeller in the mixing vessel; accelerating the mixing impeller from an inactive state to a rotating state in which the mixing impeller rotates at a first desired speed in a first rotation direction; rotating the mixing impeller at the first desired speed for a first time tsteady,1 in the first rotation direction; changing the rotation direction of the mixing impeller, so that the mixing impeller rotates in a second rotation direction at a second desired speed; and rotating the mixing impeller at the second desired speed for a second time tsteady,2.

Abstract: A system for receiving a single-use vessel containing a mixing device has a support structure adapted to receive the single-use vessel and a drive-unit adapted to power, to control, or to power and control a mixing of contents of the single-use vessel when the single-use vessel is arranged in the support structure. The support structure and the drive-unit are provided as separate components that may be arranged both in an operating position, where the drive-unit is connectable to the mixing device of the single-use bag in the support structure, and in a separated position, where the drive-unit is separated from the support structure. The drive-unit comprises a tag reader that, in the operating position, is arranged to read a vessel tag of the single-use vessel arranged in the support structure.

Abstract: A mixing vessel for accommodating components to be mixed has a container with at least one mounting depression in a side wall of the container. The mounting depression is adapted so that a mixing impeller housing of a mixing impeller is at least partly insertable, in which at least one magnet is housed for being magnetically connectable to a drive device to be driven. A locking assembly is attachable to the mounting depression from outside for locking the mixing impeller in a storage position, in which the mixing impeller is not rotatable. The locking assembly has a magnetically active element that is adapted to interact with the magnet of the mixing impeller.

Abstract: The invention relates to a service unit that can be carried on the body of a user by means of a carrying system, having at least one power source for supplying power to electrically operated tools connectable to the power source, the power source being formed from at least one rechargeable battery. The invention also relates to a method for monitoring and documenting maintenance work. The invention is distinguished in that the carrying system has an integrated computation and documentation unit for monitoring and documenting maintenance work, wherein the computation and documentation unit is powered from the power source, wherein the computation and documentation unit is connected to at least one motion sensor and/or locating sensor and wherein the motion sensor is arranged on the tool or the hand of the user.

Abstract: A mixing vessel for accommodating components to be mixed has a container with at least one mounting depression in a side wall of the container. The mounting depression is adapted so that a mixing impeller housing of a mixing impeller is at least partly insertable, in which at least one magnet is housed for being magnetically connectable to a drive device to be driven. A locking assembly is attachable to the mounting depression from outside for locking the mixing impeller in a storage position, in which the mixing impeller is not rotatable. The locking assembly has a magnetically active element that is adapted to interact with the magnet of the mixing impeller.

Abstract: A mixing and thawing device (1) has a rocker drive (2) and a bag holder (3) for holding a bag (7). The bag holder (3) has a base part (8) and a lid part (9) that enclose a holding space (10) for the bag (7). A heating element (11) is arranged in the base part (8). Thus, the holding space (10) is designed as a heat-insulating closed chamber. Interconnected intermediate spaces (14, 15) are arranged between the bag (7) and the base part (8) and between the bag (7) and the lid part (9). One or more flow generators (16) are provided to generate a circulating fluid flow (17).

Abstract: A computer system and computer-implemented method are described for controlling and monitoring a process to produce a chemical, pharmaceutical or biotechnological product. The method includes providing a database that stores sets of process parameters to control and monitor a plurality of processes performed in order to produce products, receiving a set of characterizing process parameters that characterize the process, identifying a first set process parameters from the stored sets of process parameters, and controlling and monitoring the process using a successful trajectory that includes a time-based profile of measurements.