Abstract: An implant (prosthesis) comprising a batch of a mixture of porous grains/granular material of tissue-compatible type and disintegrated tissue-compatible biological material (preferably endogenous material, such as bone meal). The batch further comprises a component which allows moulding or modelling of the batch, and the batch is enclosed in a pouch or wrap made of a flexible tissue-compatible material and having pores/apertures/perforations or the like of a size which allows outgrowth and ingrowth of tissue of the biological material. The implant is applicable in many contexts, such as a fixing agent for a hip-bone prosthesis, as a filler in plastic surgery and as a bone growth promoting agent when treating rheumatism.

Abstract: A method for inserting a plug into a hole formed in a cranial bone by rotating the plug to insert. The plug having a body with a first end, a second end, and a peripheral surface interposed there between, the first end is slightly larger than the second end. The peripheral surface further includes irregularly distributed projections.

Abstract: An implant (prosthesis) comprises biological material in its surface intended to face the body tissue. The surface is formed of a layer (3) consisting of a mixture of grains (5) of tissue-compatible type and disintegrated tissue-compatible biological material (4).In a method of making the implant, an implant body (2) and a mixture of grains (5) of tissue-compatible type and disintegrated tissue-compatible biological material (4) as well as a nutrient solution (6) for the latter are placed in a mould (8). The biological material is allowed to grow in the mould, both out to the boundary wall of the mould cavity and in to the implant body.