Patents by Inventor Lars GADTKE

Lars GADTKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REVERSAL BINDING AGENTS FOR ANTI-NATRIURETIC PEPTIDE RECEPTOR I (NPRI) ANTIBODIES AND USES THEREOF
    Publication number: 20240052042
    Abstract: The present disclosure relates to use of reversal agents which specifically bind to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies or antigen binding fragments thereof, and reverse one or more effects of the anti-NPR1 antibody or antigen binding fragments thereof (e.g., hypotensive effects).
    Type: Application
    Filed: December 13, 2021
    Publication date: February 15, 2024
    Inventors: Yuichiro ADACHI, Jennifer R. ALLPORT-ANDERSON, Shaun R. COUGHLIN, John Louis DIENER, Lars GADTKE, Felix HARTLEPP, Tiancen HU, Alexander Wolfgang KOCH, Kathrin LADETZKI-BAEHS, Michael John ROMANOWSKI, Cesare RUSSO, Xenia Karola WEZLER, Xiaoling XIE
  • NATRIURETIC PEPTIDE RECEPTOR 1 ANTIBODIES AND METHODS OF USE
    Publication number: 20230365674
    Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.
    Type: Application
    Filed: March 30, 2023
    Publication date: November 16, 2023
    Inventors: John Louis DIENER, Lars GADTKE, Felix HARTLEPP, Tiancen HU, Kathrin LADETZKI-BAEHS, Michael John ROMANOWSKI, Cesare RUSSO, Xenia WEZLER, Xiaoling XIE
  • NATRIURETIC PEPTIDE RECEPTOR 1 ANTIBODIES AND METHODS OF USE
    Publication number: 20220356242
    Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.
    Type: Application
    Filed: June 16, 2021
    Publication date: November 10, 2022
    Inventors: John Louis DIENER, Lars GADTKE, Felix HARTLEPP, Tiancen HU, Kathrin LADETZKI-BAEHS, Michael John ROMANOWSKI, Cesare RUSSO, Xenia WEZLER, Xiaoling XIE
  • Natriuretic peptide receptor 1 antibodies and methods of use
    Patent number: 11066469
    Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: July 20, 2021
    Assignee: NOVARTIS AG
    Inventors: John Louis Diener, Lars Gadtke, Felix Hartlepp, Kathrin Ladetzki-Baehs, Michael Romanowski, Cesare Russo, Xenia Wezler
  • NATRIURETIC PEPTIDE RECEPTOR 1 ANTIBODIES AND METHODS OF USE
    Publication number: 20200392225
    Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 17, 2020
    Inventors: John Louis DIENER, Lars GADTKE, Felix HARTLEPP, Tiancen HU, Kathrin LADETZKI-BAEHS, Michael ROMANOWSKI, Cesare RUSSO, Xenia WEZLER, Xiaoling XIE