Patents by Inventor Lars Holmgren
Lars Holmgren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7963560Abstract: The invention discloses an anti-skid mechanism operating device (1) for vehicles comprising an operating unit (2) and an operating arm (3) pivotally supported thereby and intended to carry a rotary anti-skid device (4) and to operate the latter between an active and a passive position. The operating device (2) comprises a worm gear (6) and a driven worm (5) adapted to engage said worm gear (6) for operation of the operating arm (3). The driven worm (5) is resiliently displaceable along an axis (A) of said worm (5).Type: GrantFiled: December 13, 2006Date of Patent: June 21, 2011Assignee: VBG AB (Publ)Inventor: Lars Holmgren
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Publication number: 20090272210Abstract: The invention discloses an anti-skid mechanism operating device (1) for vehicles comprising an operating unit (2) and an operating arm (3) pivotally supported thereby and intended to carry a rotary anti-skid device (4) and to operate the latter between an active and a passive position. The operating device (2) comprises a worm gear (6) and a driven worm (5) adapted to engage said worm gear (6) for operation of the operating arm (3). The driven worm (5) is resiliently displaceable along an axis (A) of said worm (5).Type: ApplicationFiled: December 13, 2006Publication date: November 5, 2009Inventor: Lars Holmgren
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Publication number: 20090060915Abstract: The present invention relates to prophylactic or therapeutic treatments for hindering blood vessel formation (for example, angiogenesis) for example for hindering tumour growth. In particular, the invention relates to a vaccine or medicament comprising a whole angiomotin molecule or a fragment thereof which may be used to generate immune responses to angiomotin. The invention also provides antibodies specific for a whole angiomotin molecule or a fragment thereof for use in prophylactic or therapeutic treatments.Type: ApplicationFiled: April 28, 2006Publication date: March 5, 2009Applicant: BIOINVENT INTERNATIONAL ABInventor: Lars Holmgren
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Patent number: 7445063Abstract: A drill bit assembly for direct removal of rock with a rotatable bit assembly (5) that includes a plurality of cutters or choppers (7). According to the invention, an number of cutters (7) are so disposed in relation to each other or the bit assembly (5) that a subsequent cutter (7b), seen in the direction of rotation, will engage an edge created by the action of preceding cutter (7a).Type: GrantFiled: April 7, 2004Date of Patent: November 4, 2008Assignee: Atlas Copco Secoroc ABInventor: Lars Holmgren
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Patent number: 7445062Abstract: An arrangement for replenishing lubricating grease in drill cutters (3) that include a conical outer barrel (7) which is rotatable about a shaft (5) disposed centrally in the cutter, wherein there is provided in the cutter shaft (5) a passageway (16) that extends along the shaft from the cutter end of largest diameter and that connects with a transverse passageway (18) which opens into a bearing-accommodating space (13) in the cutter for delivering lubricating grease to the space (13), and wherein a lubricating nipple (19) is provided on the cutter end wall of largest diameter and functions to allow lubricating grease to be released from the bearing-accommodating space (13).Type: GrantFiled: September 14, 2007Date of Patent: November 4, 2008Assignee: Atalas Copco Secoroc ABInventors: Jonas Thuresson, Lars Holmgren
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Publication number: 20080095789Abstract: A vaccine for preventing formation of blood vessels, for example neoangiogenesis, as well as repressing existing vascularization associated with tumors and other diseases, comprising angiomotin, for example as a whole molecule or fragment thereof or encoded as a gene or mRNA, or administered as dendritic cells (DC cells) expressing angiomotin, which may be utilized to generate immune responses to the angiomotin molecule. Inhibition of angiogenesis and delay in tumor outgrowth in animal models of cancer is achieved.Type: ApplicationFiled: December 20, 2004Publication date: April 24, 2008Inventors: Rolf Kiessling, Lars Holmgren
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Publication number: 20080000695Abstract: An arrangement for replenishing lubricating grease in drill cutters (3) that include a conical outer barrel (7) which is rotatable about a shaft (5) disposed centrally in the cutter, wherein there is provided in the cutter shaft (5) a passageway (16) that extends along the shaft from the cutter end of largest diameter and that connects with a transverse passageway (18) which opens into a bearing-accommodating space (13) in the cutter for delivering lubricating grease to the space (13), and wherein a lubricating nipple (19) is provided on the cutter end wall of largest diameter and functions to allow lubricating grease to be released from the bearing-accommodating space (13).Type: ApplicationFiled: September 14, 2007Publication date: January 3, 2008Applicant: ATLAS COPCO SECOROC ABInventors: Jonas Thuresson, Lars Holmgren
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Publication number: 20070175664Abstract: A drill bit assembly for direct removal of rock with a rotatable bit assembly (5) that includes a plurality of cutters or choppers (7). According to the invention, an number of cutters (7) are so disposed in relation to each other or the bit assembly (5) that a subsequent cutter (7b), seen in the direction of rotation, will engage an edge created by the action of preceding cutter (7a).Type: ApplicationFiled: April 7, 2004Publication date: August 2, 2007Inventor: Lars Holmgren
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Publication number: 20060249311Abstract: An arrangement for replenishing lubricating grease in drill cutters (3) that include a conical outer barrel (7) which is rotatable about a shaft (5) disposed centrally in the cutter, wherein there is provided in the cutter shaft (5) a passageway (16) that extends along the shaft from the cutter end of largest diameter and that connects with a transverse passageway (18) which opens into a bearing-accommodating space (13) in the cutter for delivering lubricating grease to the space (13), and wherein a lubricating nipple (19) is provided on the cutter end wall of largest diameter and functions to allow lubricating grease to be released from the bearing-accommodating space (13).Type: ApplicationFiled: March 14, 2003Publication date: November 9, 2006Applicant: ATLAS COPCO SECOROC ABInventors: Jonas Thuresson, Lars Holmgren
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Patent number: 6908898Abstract: The present invention provides the sequence of a protein capable of acting as an angiostatin receptor as well as the nucleic acid sequence thereof. The invention also relates to the use thereof in screening methods, wherein novel substances are created exhibiting the same advantageous anti-angiogenic properties as angiostatin.Type: GrantFiled: June 14, 1999Date of Patent: June 21, 2005Inventors: Lars Holmgren, Boris Troyanovsky
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Publication number: 20040141978Abstract: The present invention provides the sequence of a protein capable of acting as an angiostatin receptor as well as the nucleic acid sequence thereof. The invention also relates to the use thereof in screening methods, wherein novel substances are created exhibiting the same advantageous anti-angiogenic properties as angiostatin.Type: ApplicationFiled: November 25, 2003Publication date: July 22, 2004Applicant: PHARMACIA & UPJOHN ABInventors: Lars Holmgren, Boris Troyanovsky
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Patent number: 6506596Abstract: The present invention relates to a method of of transferring genomic DNA from apoptotic bodies to engulfing cells, wherein DNA is transferred from a donor cell to a recipient cell. More specifically the method includes providing somatic donor cells comprising desired DNA; generating apoptotic bodies of said donor cells; incubation of the apoptotic bodies with engulfing recipient cells under biological conditions allowing uptake of DNA from the apoptotic bodies by said recipient cells; and optionally selecting recipient cells which have integrated DNA from the apoptotic bodies. The present method is useful in various pharmaceutical applications, such as in vaccine preparations and gene identification procedures.Type: GrantFiled: April 26, 2001Date of Patent: January 14, 2003Inventors: Anna-Lena Spetz-Holmgren, Lars Holmgren, Jan Andersson, Judah Folkman
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Patent number: 6409215Abstract: An anti-skid mechanism operating device includes an operating unit and an operating arm pivotally supported thereby and intended to carry a rotary anti-skid and to operate the latter between an active position and a passive position. The operating unit is formed with a linear drive and a rotationally mounted rotary device, which is connected to the operating arm. A string-like drive transmission element extends essentially along the longitudinal axis of the drive, between the drive and the rotary device, in order to translate a linear movement of the drive into a pivotal movement of the operating arm in two opposite directions.Type: GrantFiled: July 25, 2000Date of Patent: June 25, 2002Assignee: VBG Produkter ABInventor: Lars Holmgren
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Publication number: 20020031521Abstract: The present invention relates to a method of of transferring genomic DNA from apoptotic bodies to engulfing cells, wherein DNA is transferred from a donor cell to a recipient cell. More specifically the method includes providing somatic donor cells comprising desired DNA; generating apoptotic bodies of said donor cells; incubation of the apoptotic bodies with engulfing recipient cells under biological conditions allowing uptake of DNA from the apoptotic bodies by said recipient cells; and optionally selecting recipient cells which have integrated DNA from the apoptotic bodies. The present method is useful in various pharmaceutical applications, such as in vaccine preparations and gene identification procedures.Type: ApplicationFiled: April 26, 2001Publication date: March 14, 2002Inventors: Anna-Lena Spetz-Holmgren, Lars Holmgren, Jan Andersson, Judah Folkman
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Patent number: 4355477Abstract: A working machine which is intended for demolishing and excavating work comprises a chassis, an upper part carried by said chassis and arranged for rotational movement relative thereto about a vertical axis, and an arm arrangement carried by the upper part and including a jib structure which is connected at one end thereof to the upper part and the other end of which carries, via an intermediate arm, a fitting for a tool, such as an excavator bucket, a chiseling device or like tool. The jib structure and the intermediate arm are connected to the upper part and to each other respectively via pivots and can be pivoted in a vertical plane by means of first and second pressure piston-cylinder devices active between the upper part and the jib structure and between the jib structure and the intermediate arm respectively. The jib structure is divided into a first, short jib section which is pivotally connected to the upper part, and a second, longer jib section which is pivotally connected to the first jib section.Type: GrantFiled: March 20, 1981Date of Patent: October 26, 1982Assignee: Aktiebolaget P. E. HolmgrenInventors: Lars Holmgren, Per-Martin Holmgren