Patents by Inventor Lars-Inge Olsson
Lars-Inge Olsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8338341Abstract: The invention provides a process for the production of a granule of a coated oxidizing compound which granule has good delayed release properties, said process comprising a) providing cores of an oxidizing compound produced by fluidized bed spray granulation, b) spraying on the oxidizing compound cores an aqueous solution of metal sili-cate in a fluidized bed, said aqueous solution comprising at least 15% by weight metal silicate, and c) drying to form a metal silicate coating layer on the oxidizing compound core, provided that the amount of metal silicate coating layer is at least 8%, preferably at least 10% by weight based on the total weight of the granule. The invention also provides such granule and well treatment fluids including such granule, and processes for use.Type: GrantFiled: October 15, 2008Date of Patent: December 25, 2012Assignees: Kemira Kemi AB, Kemira Chemicals, Inc.Inventors: Mona Ezzelarab, Carl Aften, Carolina Andersson, Cecilia Johansson, Richard Lalama, Geoffrey Monteith, Lars-Inge Olsson, Ajse Sandqvist, Frank Schinkel, Markus Svensson, Walter Watson, Caroline Wegner
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Patent number: 8183247Abstract: The present invention relates to novel boron comprising compounds, to pharmaceutical compositions comprising said compounds, to the therapeutic use of said compounds, and to a process for preparation of said compounds. The compounds are useful in boron neutron capture therapy (BNCT).Type: GrantFiled: August 17, 2006Date of Patent: May 22, 2012Assignee: Hammercap ABInventors: Lars-Inge Olsson, Erwan Arzel, Arne Eek
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Publication number: 20100248998Abstract: The invention provides a process for the production of a granule of a coated oxidizing compound which granule has good delayed release properties, said process comprising a) providing cores of an oxidizing compound produced by fluidized bed spray granulation, b) spraying on the oxidizing compound cores an aqueous solution of metal sili-cate in a fluidized bed, said aqueous solution comprising at least 15% by weight metal silicate, and c) drying to form a metal silicate coating layer on the oxidizing compound core, provided that the amount of metal silicate coating layer is at least 8%, preferably at least 10% by weight based on the total weight of the granule. The invention also provides such granule and well treatment fluids including such granule, and processes for use.Type: ApplicationFiled: October 15, 2008Publication date: September 30, 2010Inventors: Mona Ezzelarab, Carl Aften, Carolina Andersson, Cecilia Johansson, Richard Lalama, Geoffrey Monteith, Lars-Inge Olsson, Ajse Sandqvist, Frank Schinkel, Markus Svensson, Walter Watson, Caroline Wegner
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Publication number: 20090227539Abstract: The present invention relates to novel boron comprising compounds, to pharmaceutical compositions comprising said compounds, to the therapeutic use of said compounds, and to a process for preparation of said compounds. The compounds are useful in boron neutron capture therapy (BNCT).Type: ApplicationFiled: August 17, 2006Publication date: September 10, 2009Applicant: Hammercap ABInventors: Lars-Inge Olsson, Erwan Arzel, Arne Eek
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Patent number: 6673819Abstract: The present invention relates to novel compounds of Formula I, and pharmaceutically acceptable salts thereof, as antibacterial agents. The compounds of the present invention are nitric oxide releasing derivatives of proton pump inhibitors (NO-releasing PPIs). In further aspects, the invention relates to compounds of the invention for use in therapy; to processes for preparation of such new compounds; to pharmaceutical compositions containing at least one compound of the invention, or a pharmaceutically acceptable salt thereof, as active ingredient; and to the use of the active compounds in the manufacture of medicaments for the medical use indicated above. The invention also relates to new intermediates for use in the preparation of the novel compounds. Additionally the present invention relates to co-administration of NO-releasing PPIs with other known medicaments.Type: GrantFiled: December 20, 2001Date of Patent: January 6, 2004Assignee: AstraZeneca ABInventors: Rolf Bergman, Arne Eek, Lars-Inge Olsson, Per Lindberg
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Publication number: 20020111370Abstract: The present invention relates to novel compounds of Formula I, and pharmaceutically acceptable salts thereof, as antibacterial agents. The compounds of the present invention are nitric oxide releasing derivatives of proton pump inhibitors (NO-releasing PPIs). In further aspects, the invention relates to compounds of the invention for use in therapy; to processes for preparation of such new compounds; to pharmaceutical compositions containing at least one compound of the invention, or a pharmaceutically acceptable salt thereof, as active ingredient; and to the use of the active compounds in the manufacture of medicaments for the medical use indicated above. The invention also relates to new intermediates for use in the preparation of the novel compounds. Additionally the present invention relates to co-administration of NO-releasing PPIs with other known medicaments.Type: ApplicationFiled: December 20, 2001Publication date: August 15, 2002Inventors: Rolf Bergman, Arne Eek, Lars-Inge Olsson, Per Lindberg
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Patent number: 5968953Abstract: New compounds of the formula (A) ##STR1## a process for their preparation and their use in the manufacture of pharmaceutical preparations. The new compounds have both local anaesthetic and analgesic effect.Type: GrantFiled: April 22, 1998Date of Patent: October 19, 1999Assignee: Astra ABInventors: Anna-Lena Ask, Lars-Inge Olsson, Rune Sandberg
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Patent number: 5756520Abstract: New compounds of the formula (A) ##STR1## a process for their preparation and their use in the manufacture of pharmaceutical preparations. The new compounds have both local anaesthetic and analgesic effect.Type: GrantFiled: March 24, 1995Date of Patent: May 26, 1998Assignee: Astra ABInventors: Anna-Lena Ask, Lars-Inge Olsson, Rune Sandberg
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Patent number: 5556855Abstract: A compound of the formula Het--NR--SO.sub.2 --Ph.sup.2 --A--Ph.sup.1 (COOH)(OH) and tautomic form, salts, solvates, C.sub.1-6 alkyl esters and pharmaceutical compositions of the compound. Ph.sup.1 and Ph.sup.2 are benzene rings with the proviso that carboxy and hydroxy are ortho to one another. Het includes an optionally substituted heterocyclic ring which includes conjugated double bonds and binds to nitrogen in NR. The compound is characterized in that A is a bridge which is stable against reduction because it is not azo, and in that R is hydrogen or lower alkyl.The invention also includes the preparation of the compound and its use as a drug, particularly for treating autoimmune diseases.Type: GrantFiled: December 29, 1994Date of Patent: September 17, 1996Assignee: Pharmacia ABInventors: Hubert Agback, Leif Ahrgren, Thomas Berglindh, Martin Haraldsson, G oran Smedeg.ang.rd, Lars-Inge Olsson
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Patent number: 5403930Abstract: A compound of the formula Het--NR--SO.sub.2 --Ph.sup.2 --A--Ph.sup.1 (COOH)(OH) and tautomic form, salts, solvates, C.sub.1-6 alkyl esters and pharmaceutical compositions of the compound. Ph.sup.1 and Ph.sup.2 are benzene rings with the proviso that carboxy and hydroxy are ortho to one another. Het includes an optionally substituted heterocyclic ring which includes conjugated double bonds and binds to nitrogen in NR. The compound is characterized in that A is a bridge which is stable against reduction because it is not azo, and in that R is hydrogen or lower alkyl.The invention also includes the preparation of the compound and its use as a drug, particularly for treating autoimmune diseases.Type: GrantFiled: October 7, 1993Date of Patent: April 4, 1995Assignee: Pharmacia ABInventors: Hubert Agback, Leif Ahrgren, Thomas Berglindh, Martin Haraldsson, Goran Smedeg.ang.rd, Lars-Inge Olsson
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Patent number: 5354792Abstract: The invention relates to a flowability improving agent comprising a combination, calculated on a dry product, of: A) 60-99% by weight of a sulphonated melamine-formaldehyde resin, a sulphonated melamine-urea-formaldehyde resin or a sulphonated naphthalene-formaldehyde resin; C) 0.5-40% by weight of a boron containing polyhydroxycarboxylic acid or a water-soluble salt of such an acid and optionally D) 0.5-30% by weight of a compound with formulaAr O--(R.sub.1).sub.n --R.sub.2where Ar is unsubstituted or substituted benzene moiety or naphthalene moiety, R.sub.1 is an oxyethylene group; --CH.sub.2 CH.sub.2 O--or an oxypropylene group; ##STR1## an oxyethylene chain or an oxypropylene chain with up to fifteen oxyethylene groups or oxypropylene groups or a combination of oxyethylene groups and oxypropylene groups to a chain where the sum of these groups is at most fifteen; the mean value n for n is 1-15 and R.sub.2 is hydrogen or a phosphonate group with the formula ##STR2## where M.sub.1 and M.sub.Type: GrantFiled: August 6, 1992Date of Patent: October 11, 1994Assignee: Perstorp ABInventors: Lars-Inge Olsson, Kent Hamacek
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Patent number: 5302718Abstract: A compound of the formula Het--NR--SO.sub.2 --Ph.sup.2 --A--Ph.sup.1 (COOH)(OH) and tautomeric form, salts, solvates, C.sub.1-6 alkyl esters and pharmaceutical compositions of the compound. Ph.sup.1 and Ph.sup.2 are benzene rings with the proviso that carboxy and hydroxy are ortho to one another. Het includes an optionally substituted heterocyclic ring which includes conjugated double bonds and binds to nitrogen in NR. The compound is characterized in that A is a bridge which is stable against reduction because it is not azo, and in that R is hydrogen or lower alkyl.The invention also includes the preparation of the compound and its use as a drug, particularly for treating autoimmune diseases.Type: GrantFiled: November 9, 1992Date of Patent: April 12, 1994Assignee: Kabi Pharmacia ABInventors: Hubert Agback, Leif Ahrgren, Thomas Berglindh, Martin Haraldsson, Goran Smedegard, Lars-Inge Olsson